These data come from the ToxCast and Tox21 programs and are all curve-fit using the ToxCast Data Pipeline and released as part of a database known as InvitroDB. EPAs Toxicity Forecaster (ToxCast) is a collection of bioactivity screening data from heterogeneous assay platforms for thousands of chemicals of interest to the EPA. ToxCast is a multi-year effort launched in 2007 that uses a growing list of medium and high throughput in vitro screening assays to expose living cells, isolated proteins, or other biological molecules to chemicals. The cells or proteins are then screened for changes in biological activity that may suggest potential toxic effects. Learn more about the ToxCast program.