Best Spider-Man Villains

Miles Warren was a professor at Empire State University and had a big time crush on Gwen Stacy. When the blonde died, he blamed Spider-Man and swore vengeance. Jackal would often hire others for his dirty work (even Punisher), but in the end it was his involvement in the mostly hated 90s event, The Clone Saga, that defined his legacy. Fortunately for his reputation, Jackal was behind the better story, Spider-Island. The green genius unleashed engineered bed bugs in Manhattan, giving people Spider-Man's powers. Warren seemingly met his end from the Spider-Queen.

The member of an ancient race, Morlun only had a few appearances, but they were undeniably brutal. Morlun was able to lay the smack-down on Spider-Man like no other (even eating one of Parker's eyes). No matter how hard he fought, Spidey stood no match against this unstoppable creature and barely survived the first time by poisoning the enemy. The life-draining villain rose from the dead to battle the hero yet again. Morlun stalked and taunted him for hours, shrugging off the best strikes Spider-Man had to offer. After a lengthy battle, Spider-Man was rushed to the hospital and placed on life support. The vampiric villain went to finish the job, but Mary Jane tried to stop him. Morlun snapped her wrist like a twig, and the violence against his lover rejuvenated Spider-Man for one last feral attack. Morlun was killed by this new version of Spider-Man, but just like other villains who refuse to die, he later appeared in Black Panther.

Sergei Kravinoff is a man seeking the ultimate challenge. This hunter has defeated the planet's most dangerous animals with nothing but his bare hands. When Spider-Man came into the spotlight it presented a new hunt for him. With decades of experience, this villain became even deadlier by experimenting with potions that would give him the physicals to compete with Parker.

Kraven would finally find happiness when he landed a poison dart on Spider-Man's neck and quickly defeated him. At his mercy, Kraven shot Spider-Man with a tranquilizer and buried the fallen hero. Spending two weeks underground, Kraven dressed as Spider-Man and proved (in his mind) to be his superior by stopping crime and defeating the sewer-dwelling enemy, Vermin. When Spider-Man finally came to, Kraven swore his hunt was over and there was nothing left to live for. The Russian then took his own life, only to be brought back recently in Joe Kelly's story, Grim Hunt. Much to his displeasure, Sergei wants to return to the grave, but can only die at the hands of Spider-Man. I say now that he has a healing factor, let's see the real ultimate hunt: Kraven vs Wolverine!

The founding father of the Sinister Six, Doctor Octopus has continually battled Spider-Man since Amazing Spider-Man #3. The former atomic researcher and nuclear physicist was behind the death of George Stacy and even tried to marry Aunt May! The years of encounters with Parker have taken a toll on Doctor Octopus and he's running out of time before those lasting injuries put him to rest. Facing this realization, Otto Octavius has re-formed the Sinister Six and appears to be more determined than ever. This year at New York Comic Con, Marvel teased that the mastermind now has global plans of destruction. This is going to be a good year for the classic foe.