Tolerance occurs when the brain adjusts to more dopamine over time. This results in a decrease in the high experienced after first taking the medication. They could also take more medication to get the same dopamine effects.
There are many factors that can predict whether a person will become dependent on drugs. There are many factors that can influence the likelihood of an addict developing, such as genetic, environmental, or developmental characteristics. Predisposing characteristics are what increase the likelihood of a person becoming addicted to drugs.
                
 
Over time, the brain adapts to the extra dopamine and reduces the amount of high they feel when taking the drug. This phenomenon is called tolerance. In an effort to feel the same pleasure as the dopamine, they may take more medication.
 
It is possible to become addicted to opioids, and other narcotic pain pills, legally or illegally. This epidemic is currently being experienced in the United States. In 2018, opioids contributed to the deaths of nearly two-thirds all drug overdose victims.
You may initially decide to use a medication because you love the way it makes me feel. It is possible to regret the decision. You may believe you have full control over how many and how often you use your medication. The way your brain functions can be affected by repeated medication use. These alterations can affect the body for a significant time. They may cause you to lose your control and lead to other activities that could be harmful to you.
Comparison of Addiction and Abuse: Tolerance, or tolerance, refers the abuse of drugs. Either you use more medication than recommended or you use a substitute prescription. Drug abuse can make you feel happy, relieve tension, and ignore reality. You may be able to modify your bad habits or quit entirely. 
                                            
                                             
These steps will help you avoid becoming dependent on pain relievers. Your doctor should know about your family's history of drug abuse or addiction. This will help them to prescribe the best medication for you.
It is normal for people to develop a tolerance to pain medication. They may need to increase their pain relief dosages. This is normal and does not mean that you are addicted. For pain management, higher dosages may be necessary in cases of addiction. If you experience discomfort, consult your doctor.
Do not delay getting help. If your drug use is excessive or causing you concern, talk to your doctor. Sometimes it can take time to overcome a drug addiction. There is no cure for drug addiction, but therapy can help you stop using drugs and keep you clean. You may need counseling, medication, or both. Talk to your doctor about the best treatment for you. 
  
Get help right now; don't wait. Talk to your doctor immediately if your drug addiction is severe or out of control. The process of overcoming a drug addiction may take time. Even though there is no cure, therapy may be able to help with drug abstinence. The treatment options available to you include medication, therapy sessions, or a combination. Talk with your healthcare practitioner to determine the best course of treatment for you.
Many people are confused as to how or why other people become addicted. Some people mistakenly think that people who use drugs lack morality or willpower. If they made the decision to stop using drugs, they wouldn't be able to stop. Drug addiction can be a complex problem. Overcoming it requires more than positive thinking and strong willpower. The brain effects of drug abuse can make it difficult for even the most determined addicts to quit. Scientists now have a better understanding of how drugs affect brain function and can offer therapies that help people get clean and live productive lives.
Addiction can be defined as a chronic disorder characterized by an excessive drug seeking behavior and the use of drugs without regard to the adverse effects on one’s health. Addiction can be hard to control. Most people take drugs freely, but chronic drug abuse can cause brain changes that make it difficult for individuals to maintain self-control and hinder their ability to resist the temptation to use drugs. Relapsing drug addiction is often called "relapsing" because the brain changes that can result from it can be very long-lasting. This indicates that people who have been treated for drug addiction may be more likely to resume drug use after a break.
                                             
The "reward circuit" of the brain is affected by most drugs, which elicit pleasure and flood the brain with the chemical messenger dopamine. A person is motivated to repeat actions necessary for survival, such as eating and spending time with loved ones, when a reward system is working effectively. Dopamine rushes in the reward circuit encourage enjoyable but harmful behaviours like drug use, encouraging users to keep engaging in the action.
The brain adjusts when a person uses drugs by lowering the capacity of cells in the reward circuit to react to it. As a result, the individual experiences a lower high than they did when they initially started using the drug. This is a phenomenon known as tolerance. To try to get the same high, they can use more of the substance. These brain changes frequently result in the person's ability to enjoy formerly enjoyable activities like eating, sex, or social interactions diminishing with time.
Long-term usage also alters other chemical circuits and systems in the brain, which impacts cognitive processes including memory, stress management, learning, and behaviour. Many drug users continue to use drugs despite being aware of these negative effects; this is typical of addiction. 
Your brain will eventually get used to the extra dopamine. You might need to use more dopamine to feel the same pleasure. Other things that you love, like eating and spending time with your family, might offer less pleasure.