MHP Secretagogue-One review

MHP Secretagogue-One review
Overall
2.3
  • Anti-Aging Benefits
  • Fitness, Athletic and Muscle-building Benefits
  • Recovery and Rehabilitation
  • Energy and Vitality Benefits
  • Cognitive Function/Brain Health Improvement
  • Libido and Sexual Health Benefits
  • Sleep Quality Optimization & Stress Control
  • Health and Longevity
  • Weight Management Benefits
Comments Rating 0 (0 reviews)

Summary

MHP Secretagogue-One HGH is a decent HGH product, that is made by MHP. The product contains sufficient quantities of amino acids and growth factors compounds, although missing on other kinds of HGH boosting ingredients.

However, this product represents the common issue with proprietary HGH supplements โ€“ big promises with little substance. While the amino acids provide some basic benefits, the pituitary extracts are questionable and dosing transparency is poor. The high price tag makes it hard to recommend when simpler, cheaper alternatives exist. Most users would benefit more from proven sleep optimization and basic amino acid supplementation rather than this expensive blend of mostly unknown quantities.

Pros

  • Decent quality and diversity of ingredients
  • Well known company, been in business since a long time
  • Contains beneficial amino acids like arginine and glycine that support natural growth hormone production
  • Includes GABA which can improve sleep quality and indirectly benefit hormone levels
  • Comprehensive amino acid profile covers multiple pathways for potential benefits

Cons

  • The product lacks certain crucial ingredients like anti-somatostatin compounds, choline supplements etc.
  • Proprietary blend format hides actual ingredient doses making effectiveness impossible to judge
  • Animal pituitary extracts are outdated and potentially risky with unclear quality standards
  • Overpriced compared to buying individual proven ingredients separately
  • Lacks modern, research-backed HGH supporting compounds found in better formulations

 

Quick Summary

Pricey amino blend with questionable pituitary extracts. Overall Rating: 2.3/5

Strengths: Contains solid growth hormone supporting amino acids, includes GABA for sleep support, decent arginine and lysine doses for basic benefits.

Weaknesses: Proprietary blend hides actual doses, uses animal pituitary extracts of unclear quality, overpriced for what you get, lacks proven HGH boosters.

Best Use: Nighttime supplement for those wanting basic amino acid support with potential mild growth hormone benefits.

Who Should Try This Product?

Beginners curious about HGH supplements who donโ€™t mind paying premium prices for unproven ingredients. Those specifically interested in amino acid blends for general wellness might find some value.

Better alternatives: GenF20 Plus offers more proven ingredients at similar price points. For budget-conscious users, basic arginine and glycine supplements provide the main benefits at fraction of the cost.

Who Should Look Elsewhere?

Experienced supplement users seeking proven HGH support should skip this. Anyone concerned about animal-derived ingredients or wanting transparent dosing information will be disappointed. Those on tight budgets can get better value elsewhere.

Recommended alternatives

  1. Genf20 Plus (Maximum HGH boost optimization, with 14 different HGH precursors + Alpha-GPC workout spray)
  2. Hi-tech Somatomax (Combines GABA with Phenibut โ€“ advanced formula for sleep focused HGH enhancement)
  3. NutraHarmony GABA L-theanine (Best value-for-money affordable GABA sleep supplement with L-theanine, B6, Magnesium for sleep support)
  4. Regains Max (comprehensive amino acids profile in an HGH supplement)

Also read: Master List of Top recommended HGH supplements

MHP Secretagogue One: Complete Product Overview

MHP Secretagogue-One markets itself as an advanced growth hormone support supplement containing amino acids and compounds designed to boost natural IGF-1 production. While the product includes several beneficial amino acids, the proprietary blend format and questionable ingredients make it difficult to recommend over more transparent alternatives.

The supplement combines traditional amino acids with controversial animal-derived extracts, positioning itself as a nighttime recovery formula. Each packet delivers a blend of growth-supporting compounds, though the actual effectiveness remains questionable due to undisclosed dosing and outdated ingredients.

Ingredient Breakdown

Glycine (Unknown dose in 5,000mg blend) Glycine is one of the most researched amino acids for growth hormone support, with studies showing it can increase GH levels when taken before bed. This amino acid also supports better sleep quality, which indirectly benefits hormone production and recovery.

L-Glutamine (Unknown dose in 5,000mg blend) L-Glutamine serves as fuel for immune cells and may help preserve muscle mass during intense training periods. While beneficial for recovery, its direct impact on growth hormone levels is minimal compared to other amino acids in the blend.

L-Tyrosine (Unknown dose in 5,000mg blend) L-Tyrosine acts as a precursor to important neurotransmitters like dopamine, which can influence growth hormone release. This amino acid may also help improve focus and mental clarity during stressful training periods.

GABA (Unknown dose in 5,000mg blend) GABA can promote relaxation and improve sleep quality, which indirectly supports natural growth hormone production since GH peaks during deep sleep. Some studies suggest GABA supplementation may directly stimulate growth hormone release, though results are mixed.

L-Arginine (Unknown dose in 5,000mg blend) L-Arginine is well-researched for its ability to stimulate growth hormone release, particularly when taken on an empty stomach. This amino acid also supports nitric oxide production, which can improve blood flow and nutrient delivery to muscles.

Pyroglutamic Acid (Unknown dose in 5,000mg blend) Pyroglutamic acid may enhance cognitive function and could potentially influence neurotransmitter activity related to hormone release. However, research on its specific effects on growth hormone is limited compared to other amino acids in the formula.

L-Lysine (Unknown dose in 5,000mg blend) L-Lysine works synergistically with arginine to enhance growth hormone release, with some studies showing the combination is more effective than either amino acid alone. This essential amino acid also supports protein synthesis and immune function.

Anterior Pituitary Substance (25mg) This animal-derived extract comes from pig pituitary glands and represents an outdated approach to hormone support. The quality, safety, and effectiveness of such extracts are questionable, and most modern supplements have moved away from these controversial ingredients.

Broad Bean Extract (10mg) Broad bean contains L-DOPA, a precursor to dopamine that may influence growth hormone release through neurotransmitter pathways. However, the 10mg dose is likely too small to produce meaningful effects compared to dedicated L-DOPA supplements.

Glycoamino Acid-Glucose Complex (4,200mg) This complex appears to be a carbohydrate delivery system designed to enhance amino acid absorption. While glucose can help with nutrient uptake, the specific benefits of this proprietary complex are unclear without independent research.

Novel Polyose Complex (1,700mg) These glucose polymers serve as a carrier matrix for the other ingredients, potentially improving bioavailability. However, the term โ€œnovelโ€ suggests this is a proprietary ingredient with limited research backing its effectiveness claims.

Usage Instructions

Take one packet mixed with 4-6 fl. oz. water at bedtime on an empty stomach. The nighttime timing aligns with natural growth hormone release patterns, though the empty stomach requirement may cause discomfort for some users.

Important Warning: This product carries a California Prop 65 warning for lead exposure, raising concerns about manufacturing quality and safety standards.

Bottom Line

MHP Secretagogue-One combines proven amino acids with questionable animal extracts in a proprietary blend that hides actual dosing information. While some ingredients like arginine and glycine have research support, the overall formula feels outdated and overpriced compared to modern alternatives with transparent labeling.

User Reviews

Our Full Evaluation of MHP Secretagogue-One

Anti-Aging Benefits: 2/5

The amino acid blend provides minimal anti-aging support, with only glycine and arginine showing modest research for skin and cellular health. The proprietary dosing and questionable pituitary extracts make it unreliable for meaningful anti-aging effects.

Fitness, Athletic and Muscle-building Benefits: 2.5/5

L-Glutamine and arginine can support muscle recovery and blood flow, but the unknown doses in the proprietary blend limit effectiveness. The combination lacks proven muscle-building compounds found in better HGH supplements.

Recovery and Rehabilitation: 3/5

The amino acid profile, particularly glutamine and glycine, can aid basic recovery processes and sleep quality. However, the modest doses and lack of modern recovery compounds prevent it from being a standout option.

Energy and Vitality Benefits: 2/5

L-Tyrosine may provide mild cognitive energy support, but the overall formula lacks stimulating compounds for noticeable vitality boosts. Most users wonโ€™t experience significant energy improvements from this nighttime supplement.

Cognitive Function/Brain Health Improvement: 2/5

GABA and L-Tyrosine offer minimal cognitive support, mainly through relaxation and neurotransmitter precursor effects. The doses are likely too low to produce meaningful brain health benefits compared to dedicated nootropics.

Libido and Sexual Health Benefits: 2/5

Arginine can support blood flow which may indirectly benefit sexual function, but the proprietary blend provides inadequate doses. The formula lacks specific compounds targeting hormonal pathways crucial for libido enhancement.

Sleep Quality Optimization & Stress Control: 3.5/5

GABA and glycine are well-researched for promoting relaxation and better sleep quality, which is the productโ€™s strongest area. The nighttime timing also aligns well with natural circadian rhythms for optimal hormone release.

Health and Longevity: 2/5

While amino acids provide basic health support, the animal pituitary extracts raise safety concerns and the lead warning suggests quality control issues. The formula lacks comprehensive longevity-supporting compounds found in better supplements.

Weight Management Benefits: 2/5

The amino acids may support lean muscle maintenance and metabolism slightly, but the formula lacks proven fat-burning or appetite-controlling ingredients. Users shouldnโ€™t expect meaningful weight management benefits from this product alone.

BrightFutures Staff

Bright Futures FITNESS is your trusted destination for evidence-based health, nutrition, and fitness insights. Our team of certified professionals, dietitians, and experienced fitness enthusiasts brings decades of hands-on experience with supplements, training, and nutrition across all fitness levelsโ€”from busy professionals and mothers balancing wellness goals to competitive bodybuilders and elite athletes. We translate complex research into practical, unbiased guidance that works for real people with real lives. Need personalized help? We offer individual supplement and stack consulting services tailored to your unique goals, lifestyle, and physiologyโ€”whether you're seeking general wellness optimization, performance enhancement, or competitive bodybuilding guidance. Contact us for a personalized consultation to discover the most effective, safe, and practical approach for your specific situation. Read more about us.

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