Quick Summary

Multi-Vitamins packed HGH supplement with decent amino acids and questionable animal extracts. Overall Rating: 3.6/5

Strengths: Comprehensive vitamin profile supports hormone production, includes proven amino acids like arginine and glycine, added green tea extract provides antioxidant benefits.

Weaknesses: Still uses proprietary blends hiding doses, contains outdated pituitary extracts from pigs, overpriced for mostly basic vitamins and amino acids.

Best Use: Nighttime supplement for those wanting vitamin support alongside basic HGH amino acids, best for users with nutrient deficiencies.

Who Should Try This Product?

People with poor diets who need both vitamin support and basic HGH benefits might find value here. Those who responded well to the original Secretagogue-One but want added nutrition could consider upgrading.

Better alternatives: Genf20 Plus offers more modern HGH support with solid, comprehensive ingredients dosing. For budget-conscious users, separate high-quality multivitamin plus arginine/glycine supplements provide better value and transparency.

Who Should Look Elsewhere?

Experienced supplement users seeking cutting-edge HGH support should skip this outdated formula. Anyone concerned about animal-derived ingredients or wanting transparent dosing will be disappointed. Those already taking a good multivitamin are paying for redundant nutrients.

Recommended alternatives

1. Genf20 Plus (Maximum HGH boost optimization, with 14 different HGH precursors + Alpha-GPC spray)
2. Regains Max (comprehensive amino acids profile in an HGH supplement. Consider stacking this with a multi-vitamin supplement like PrimeMale multivitamins.)
3. NutraHarmony GABA L-theanine (Best value-for-money affordable GABA sleep supplement with L-theanine, B6, Magnesium for sleep support)
4. Hi-tech Somatomax (Combines GABA with Phenibut – advanced formula for sleep focused HGH enhancement)

MHP Clinical Strength Secretagogue-Gold: Complete Product Overview

MHP Clinical Strength Secretagogue-Gold positions itself as an advanced anti-aging supplement designed to boost natural growth hormone production by up to 321%. Formulated by Dr. Vincent Giampapa, this “clinical strength” version expands beyond basic amino acids to include liver support, blood sugar regulation, and comprehensive nutritional cofactors.

The supplement takes a systematic approach to age management, targeting multiple pathways involved in growth hormone production and overall health. Each serving delivers a complex blend of amino acids, vitamins, minerals, and specialized extracts designed to support the body’s natural hormone production mechanisms while addressing key biomarkers of aging.

MHP Secretagogue-One vs Secretagogue-Gold: Key Differences

MHP Secretagogue-Gold represents a significant upgrade over the basic Secretagogue-One formula, expanding from a simple amino acid blend to a comprehensive anti-aging system. While Secretagogue-One contains just the core amino acids and questionable pituitary extracts, Secretagogue-Gold adds liver support compounds like milk thistle, blood sugar regulators including banaba leaf and alpha lipoic acid, immune-supporting mushroom extracts, and a complete vitamin-mineral profile.

The Gold version also includes more advanced ingredients like Alpha-GPC and phytosome green tea extract, plus removes the controversial anterior pituitary substances found in the original formula.

However, both products still use proprietary blends that hide actual ingredient doses, and the Gold version commands a higher price (at around $67 vs $52 for Secretagogue-One), for what amounts to a multivitamin combined with the same basic amino acid foundation – making it a better choice for those with poor diets or seeking comprehensive support, but potentially overpriced for users who already maintain good nutrition.

Ingredient Breakdown

Glycine (Unknown dose in 5.2g blend) Glycine remains one of the most researched amino acids for growth hormone support, with studies showing significant GH increases when taken before bed. This simple amino acid also promotes better sleep quality and supports collagen production for skin health.

L-Glutamine (Unknown dose in 5.2g blend) L-Glutamine serves as fuel for immune cells and helps maintain muscle mass during stress or intense training. While beneficial for recovery and gut health, its direct impact on growth hormone levels is modest compared to other amino acids in the formula.

GreenSelect Phytosome Green Tea Extract (Unknown dose in 5.2g blend) This specialized green tea extract uses phytosome technology to enhance absorption and provides powerful antioxidant protection. The extract may also support metabolism and fat burning, complementing the anti-aging effects of increased growth hormone.

L-Tyrosine (Unknown dose in 5.2g blend) L-Tyrosine acts as a precursor to dopamine and other neurotransmitters that can influence growth hormone release. This amino acid also helps maintain mental clarity and focus during stressful periods or intense training.

GABA (Unknown dose in 5.2g blend) GABA promotes relaxation and can improve sleep quality, which is crucial for natural growth hormone production since GH peaks during deep sleep. Some research suggests GABA may directly stimulate growth hormone release, though results vary among individuals.

Alpha-GPC (Unknown dose in 5.2g blend) Alpha-GPC provides a highly bioavailable form of choline that supports cognitive function and may enhance growth hormone release. This compound is particularly valued for its ability to cross the blood-brain barrier and support neurotransmitter production.

L-Lysine HCl (Unknown dose in 5.2g blend) L-Lysine works synergistically with arginine to enhance growth hormone release, with studies showing the combination is more effective than either amino acid alone. This essential amino acid also supports protein synthesis and immune function.

L-Citrulline (Unknown dose in 5.2g blend) L-Citrulline converts to arginine in the body and may provide more sustained nitric oxide production than direct arginine supplementation. This amino acid supports blood flow and may indirectly benefit growth hormone release through improved circulation.

L-Pyroglutamic Acid (Unknown dose in 5.2g blend) L-Pyroglutamic acid may enhance cognitive function and could potentially influence neurotransmitter activity related to hormone release. However, research on its specific effects on growth hormone is limited compared to other amino acids in the formula.

Broad Bean Extract (Unknown dose in 5.2g blend) Broad bean contains L-DOPA, a precursor to dopamine that may influence growth hormone release through neurotransmitter pathways. The extract provides a natural source of this compound, though the actual dose in the blend is unclear.

Choline Bitartrate (Unknown dose in 466mg blend) Choline bitartrate supports liver function and helps with fat metabolism, which becomes increasingly important as we age. This compound also serves as a precursor to acetylcholine, an important neurotransmitter for cognitive function.

Inositol (Unknown dose in 466mg blend) Inositol supports insulin sensitivity and may help regulate blood sugar levels, which is important for optimal growth hormone production. This compound also supports cellular health and may have mood-stabilizing effects.

Milk Thistle Extract (Unknown dose in 466mg blend) Milk thistle extract provides liver protection and detoxification support, which is crucial for processing hormones and maintaining overall health. The 80% silymarin standardization ensures a potent dose of the active compounds.

Shiitake Mushroom Extract (Unknown dose in 466mg blend) Shiitake mushrooms contain compounds that support immune function and may help regulate inflammation in the body. These mushrooms also provide B vitamins and minerals that support energy metabolism and overall health.

Maitake Mushroom Extract (Unknown dose in 466mg blend) Maitake mushrooms are known for their immune-supporting properties and may help regulate blood sugar levels. These mushrooms also contain beta-glucans that can support overall immune system function.

Reishi Mushroom Extract (Unknown dose in 466mg blend) Reishi mushrooms are adaptogenic and may help the body manage stress while supporting better sleep quality. These mushrooms have been traditionally used for longevity and may support overall hormone balance.

Banaba Leaf Extract (Unknown dose in 466mg blend) Banaba leaf extract helps regulate blood sugar levels through its corosolic acid content, which can improve insulin sensitivity. Better blood sugar control supports optimal growth hormone production and overall metabolic health.

Alpha Lipoic Acid (Unknown dose in 466mg blend) Alpha lipoic acid is a powerful antioxidant that supports cellular energy production and may help regulate blood sugar levels. This compound also supports nerve health and may help protect against age-related cellular damage.

Chromium Dinicotinate Glycinate (Unknown dose in 466mg blend) This highly bioavailable form of chromium supports glucose metabolism and insulin sensitivity, which is important for growth hormone production. Better blood sugar control also supports energy levels and overall metabolic health.

Comprehensive Vitamin and Mineral Complex (252mg total) The extensive vitamin and mineral profile provides cofactors essential for hormone production and overall health. These nutrients support energy metabolism, immune function, and cellular processes that decline with age.

Usage Instructions

Mix one stick pack in 5-6 fl. oz. of water and take on an empty stomach, preferably 2-3 hours before or after meals. For optimal results, take in the evening before bed to align with natural growth hormone release patterns.

Bottom Line

Clinical Strength Secretagogue-Gold represents a genuinely comprehensive approach to HGH support, successfully incorporating liver detoxification, blood sugar regulation, and extensive nutritional cofactors into a systematic anti-aging formula. The added ingredients provide substantial health benefits beyond basic amino acid support, with liver protection, immune enhancement, and metabolic optimization creating real value for users seeking holistic age management.

The formula shows significant advancement over basic HGH supplements, addressing multiple aging pathways simultaneously rather than relying solely on amino acid stimulation. While the proprietary blends limit dosing transparency, the comprehensive approach and quality ingredients justify the premium positioning for users wanting an all-in-one anti-aging solution.

The extensive nutrient profile provides genuine value for most users, combining effective HGH support with immune system enhancement and metabolic optimization in a single formula.

While dedicated specialists might prefer transparent single-ingredient supplements, this systematic approach offers convenience and synergistic benefits that make it a solid choice for comprehensive age management rather than basic HGH stimulation alone.

 

Our Final evaluation of MHP Secretagogue-Gold as an HGH supplement with various health benefits

Anti-Aging Benefits: 4/5

The comprehensive formula targets multiple aging pathways with antioxidants like green tea extract and alpha lipoic acid, plus liver support and blood sugar regulation. The systematic approach addressing key biomarkers of aging makes this one of the stronger anti-aging HGH supplements available.

Fitness, Athletic and Muscle-building Benefits: 3/5

The amino acid blend provides solid muscle support through glycine, glutamine, and citrulline, while the vitamin-mineral complex supports energy metabolism. However, the proprietary blends hide doses of key performance ingredients, limiting its effectiveness for serious athletes.

Recovery and Rehabilitation: 4/5

The combination of amino acids, mushroom extracts for immune support, and comprehensive B-vitamins creates a strong recovery formula. The liver support compounds and anti-inflammatory ingredients further enhance the body’s ability to recover from training stress.

Energy and Vitality Benefits: 3.5/5

The extensive vitamin-mineral profile addresses common nutrient deficiencies that affect energy levels, while blood sugar regulators help maintain stable energy. The adaptogenic mushroom extracts also support sustained vitality, though effects may take weeks to notice.

Cognitive Function/Brain Health Improvement: 3.5/5

Alpha-GPC provides excellent cognitive support by enhancing neurotransmitter production, while the comprehensive B-vitamin complex supports brain function. The adaptogenic mushrooms and blood sugar regulation also contribute to better mental clarity and focus.

Libido and Sexual Health Benefits: 2.5/5

The amino acids may support blood flow and energy levels that indirectly benefit sexual function, but the formula lacks specific compounds targeting hormonal pathways. The overall health improvements may provide modest benefits over time, but dedicated libido support would be minimal.

Sleep Quality Optimization & Stress Control: 4/5

GABA promotes relaxation while the adaptogenic mushroom extracts help manage stress responses throughout the day. The comprehensive nutrition and liver support also contribute to better overall sleep quality and stress resilience.

Health and Longevity: 4.5/5

This is the formula’s strongest area, with liver detoxification, blood sugar regulation, immune support, and comprehensive nutrition all targeting longevity pathways. The systematic approach to multiple aging biomarkers makes it genuinely effective for long-term health optimization.

Weight Management Benefits: 3/5

The green tea extract and blood sugar regulators can support healthy metabolism and fat burning, while the amino acids help preserve lean muscle mass. The comprehensive approach supports sustainable weight management better than basic HGH formulas, though dedicated fat burners would be more effective.

Immune System Support: 4/5

The combination of mushroom extracts (shiitake, maitake, reishi), comprehensive vitamins, and liver support creates excellent immune system reinforcement. This category represents a major upgrade over basic HGH supplements and addresses a key component of healthy aging.

Metabolic Health: 4/5

The blood sugar regulation through banaba leaf, alpha lipoic acid, and chromium, combined with liver support compounds, creates strong metabolic health benefits. This systematic approach to glucose control and liver function significantly enhances the overall anti-aging effects.

 

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