Author: admin, 29.04.2014Overall, candidemia rates have increased over the past 20 years in the United States, though recent rates have decreased in the past few years (Figure 1).4-8 The two places with surveillance data from the 1990s and today are Atlanta and Baltimore. CDC's lead group for the prevention and control of fungal infections in the United States and internationally through epidemiological and microbiological studies to improve the diagnosis, treatment, prevention, and control of mycotic diseases. The Fungal Epidemiology Team works to prevent disease and disability due to fungi by determining the burden of fungal infections, using available evidence to promote education and awareness of fungal diseases, address gaps in knowledge about prevention of fungal diseases, and work with domestic and international partners to provide response and support for fungal public health issues. The Fungal Service Team contributes to the prevention and control of fungal infections by facilitating detection, identification, and characterization of human fungal pathogens. The Fungal Research Team contributes to the prevention and control of fungal infections by performing research on the molecular epidemiology of fungal infections, novel detection and diagnostic methods, and fungal molecular subtyping.
Regionally limited or rare infections: prevention after hematopoietic cell transplantation.
Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study.
Through active notification by clinics with assistance from states and CDC in early October, nearly all of these exposed persons were contacted at least once and informed of their risk for fungal infection as a result of receiving injections with contaminated medication.Despite this and subsequent patient outreach efforts, CDC and public health partners remain concerned about the potential for some exposed patients to have localized fungal infections that have gone unrecognized. As one of the only public health groups in the world devoted specifically to the prevention and control of fungal infections, MDB works with domestic and international partners to determine the burden of fungal infections, respond to outbreaks, and to address public health problems related to fungal infections. Hospital-associated infections such as candidemia, a fungal bloodstream infection, are a major concern in the US.
Cryptococcus gattii infection in solid organ transplant recipients: description of Oregon outbreak cases. Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET). Update on Multistate Outbreak of Fungal Infections Associated with Contaminated Methylprednisolone Injections, 2012-2014. Cluster of Cryptococcus neoformans Infections in Intensive Care Unit, Arkansas, USA, 2013.
Utility of Real-Time PCR for detection of Exserohilum rostratum in body and tissue fluids during the multistate outbreak of fungal meningitis and other infections.
Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET).
Utility of (1-3)-B-D-glucan testing for diagnostics and monitoring response to treatment during the multistate outbreak of fungal meningitis and other infections. Whole genome analysis of Exserohilum rostratum from the outbreak of fungal meningitis and other infections.
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Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.
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Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents [PDF - 216 pages]. Contaminated product water as the source of Phialemonium curvatum bloodstream infection among patients undergoing hemodialysis. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective.
Because many of these new cases are among patients with minimal symptoms, CDC is re-emphasizing the recommendation for clinicians to remain vigilant for fungal infections, especially in patients with mild or even baseline symptoms, and consider evaluation with magnetic resonance imaging (MRI) if clinically warranted.
We conduct a yearly Mold Identification Training Course in collaboration with the Association of Public Health Laboratories. Some fungal diseases like fungal meningitis and bloodstream infections are less common than skin and lung infections but can be deadly.
In addition, of 109 different patients reporting persistent but baseline symptoms at or near the site of their spinal or paraspinal injection, 15 (14%) also had abnormal MRI findings suggestive of infection, and 27 (25%) had non-specific enhancement of soft tissue or other paraspinal structures.
Because of the possibility that some patients may have unrecognized, localized fungal infections, CDC is re-emphasizing the following recommendations for patients who received a spinal or paraspinal injection with implicated MPA:PatientsPatients who received an injection in or near their spine from one of the three implicated lots of MPA1 and who have any symptoms at or near the site of their injection should seek evaluation by their medical provider for the possibility of a localized infection, such as an epidural abscess. This includes patients who initially received steroid injections for pain and continue to have persistent baseline pain.CliniciansAs a part of continued monitoring of patients who received an injection with implicated MPA, clinicians should consider re-evaluating patients who received a spinal or paraspinal injection with implicated MPA for signs and symptoms suggestive of infection, including any symptoms at or near the site of their injection.
Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program.
Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Fourth Informational Supplement, M27-S4. Epidemiologic and molecular characterization of an outbreak of Candida parapsilosis bloodstream infections in a community hospital.
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