Candida onychomycosis fluconazole,candidiasis masculina hombre,natural remedy for candida in mouth,rectal candidiasis treatment - You Shoud Know
Author: admin, 01.07.2015Onychomycosis is a fungal infection of the fingernails or toenails that causes discoloration, thickening, and separation from the nail bed. Onychomycosis occurs in 10% of the general population, 20% of persons older than 60 years, and 50% of those older than 70 years. Other organisms include Candida, which is more common in fingernail infections (eFigure A) and in patients with chronic mucocutaneous candidiasis.1 Nondermatophyte molds are a less common cause in the general population. The classes include distal and lateral subungual onychomycosis (Figures 1 and 2), proximal subungual onychomycosis (Figure 3), superficial onychomycosis (Figure 4), and total dystrophic onychomycosis (Figure 5).
Only 50% of nail problems are caused by onychomycosis,6 and clinical diagnosis by physical examination alone can be inaccurate. The azole class includes itraconazole (Sporanox), fluconazole (Diflucan), and ketoconazole; however, ketoconazole is rarely prescribed because of drug interactions and hepatotoxicity. Systemic antifungals are the most effective treatment, with meta-analyses showing mycotic cure rates of 76% for terbinafine, 63% for itraconazole with pulse dosing, 59% for itraconazole with continuous dosing, and 48% for fluconazole. Despite treatment, the recurrence rate of onychomycosis is 10% to 50% as a result of reinfection or lack of mycotic cure.
In those with suspected superficial onychomycosis, the superficial aspect of the nail is scraped.Once the specimen has been obtained, office microscopy can be performed by preparing the samples with potassium hydroxide (KOH) 10% to 20% solution.
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