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admin | Supplements To Gain Muscle | 09.10.2013
Serum testosterone undergoes a natural daily variation in levels as shown by the chart below.
A detailed physical examination and biochemical investigation is mandatory in a person suspected of LOH. Free testosterone is calculated from measured total testosterone and SHBG or measured by a reliable free testosterone laboratory. For decades, older women have taken hormone replacements to replenish estrogen and progesterone levels lost to aging, called Menopause.
It’s not clear that naturally falling testosterone levels cause any signs and symptoms in men.
Some men experience these signs and symptoms, but don’t have unusually low levels of testosterone.
Testosterone replacement therapy can help older men deficient in the hormone reduce their risks of heart disease, diabetes, and death, according to new research presented at the annual meeting of The Endocrine Society.
The Studies found that testosterone replacement therapy reduced the metabolic syndrome risk factors and did so in a similar way in all the age ranges studied.
The testosterone replacement was given as a long-acting injection (Nebido), every three months. In a second study, the same 95 men were divided into three groups, based on age: less than 57, 57 to 63, and older than 63. They found the older men and the younger men had similar improvement in their risk factors.

It is well known that with prostate cancer, the cancer is usually dependent on testosterone. Low testosterone levels are associated with an increased risk of death, according to Robin Haring, a researcher from Germany.He evaluated data on nearly 2,000 men, aged 20 to 79, following them for seven years until August 2007. They were more likely to die of cardiovascular disease and cancer, but not of other causes. The problem area  about supplemental testosterone is the lack of knowledge on long-terms effects. We have learned during the years that hormone replacement can be beneficial but not without risk for the stimulating effects of the hormones. Studies of men who have very low levels of testosterone due to diseases and treatments may offer some clues to the role testosterone plays in a man’s body as he ages. Others may have low levels of testosterone, but don’t experience any signs and symptoms that would prompt them to seek treatment.
The potential increase in red blood cells, can theoretically boost heart attack or stroke risk.
According to those studies, testosterone deficiency can have several effects on the body, including: Decreased sexual function , Loss of bone density, Loss of muscle mass, Increase in fat mass, Reduced muscle strength, Memory loss, Mood changes and depression. Low levels of testosterone are associated with the metabolic syndrome — a cluster of risk factors such as abnormal cholesterol and high blood pressure that boost risk of heart disease, stroke, and type 2 diabetes as well as other risks to health.
Cancer must be ruled out before starting supplements, and routine prostate checkups are advised.

These problems can be seen with bodybuilders using large doses of testoterone or an equivalent derivative.
More recently, testosterone (the most important male hormone) supplements have been used by aging men to improve their quality of life, Male Menopause or Andropause has been described as the male decline in testosterone levels. Men with low testosterone have a more than twofold higher risk of death during the follow-up period. If health risks with the low supplementation to “natural” levels can induce similar problems has not be seen yet in studies, sideeffects were not significant but patients were also filtered on possible prostate problems. In 2003, the number of elderly American men taking testosterone replacement therapy was already 1 million, and the number has been growing faster in recent years. Low testosterone levels are not [yet] indicated as a disease so reimbursement by insurance is nill. Dermal patches and gels and (long acting) injections range in price between $20 – 200 monthly excluding the tests and consultation fees.  Allthough the studies show that restoring testosterone when it is low improves metabolic syndrome factors and could help prevent type 2 diabetes and cardiovascular risks as with other therapies lifestyle changes can also have a significant effect on the hormone levels and the mentioned risk factors, especially the good old watch what you eat (and how much) and exercise !

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