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admin | Natural Weight Loss Supplement | 15.07.2014
Shouldn't Adults with Growth Hormone Deficiency Be Offered Growth Hormone Replacement Therapy?
Human growth hormone is now readily available and approved for treatment of the growth hormone deficiency syndrome in adults. Grahic Jump LocationFigure 2.An alternative paradigm to explain excess death rates in patients with hypopituitarism. Anyone can submit a comment any time after publication, but only those submitted within 4 weeks of an article’s publication will be considered for print publication. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. From the Massachusetts General Hospital, Boston, Massachusetts; and the Maine Medical Center, Portland, Maine.


Requests for Reprints: Anne Klibanski, MD, Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit Street, BUL457B, Boston, MA 02114.
Background: Patients with adult-onset growth hormone deficiency have reduced bone density and increased fat mass. One month after publication, editors review all posted comments and select some for publication in the Letters section of the print version of Annals.
Effects of Physiologic Growth Hormone Therapy on Bone Density and Body Composition in Patients with Adult-Onset Growth Hormone Deficiency: A Randomized, Placebo-Controlled Trial. Recombinant Human Growth Hormone, Insulin-like Growth Factor 1, and Combination Therapy in AIDS-Associated Wasting: A Randomized, Double-Blind, Placebo-Controlled Trial. Bernard Kliman for assistance with patient recruitment, Douglas Hayden for contributions to the statistical analysis, Dr.


Long-term studies in patients receiving appropriate comprehensive management for other hormonal deficiencies and for concomitant abnormalities will be required to convince physicians of the utility and safety of growth hormone replacement therapy.
Leng Jiang for doing echocardiography, Jennifer Lord for study coordination and data entry, Jaime Paz for assistance with exercise testing, and the staff of the General Clinical Research Center at the Massachusetts General Hospital for their dedicated patient care.
Growth factor therapy at the dosages used in this study is not recommended because the magnitude of weight gain was modest and improvements in quality-of-life measures varied.Deceased.



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