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admin | Natural Testosterone Replacement | 19.07.2014
Citrulline Malate – A dual-threat: Provides huge boosts to training volume with the metabolic intermediate malate and stimulates nitric oxide production with citrulline. Choline Complex – Choline Bitartrate and CDP choline create acetylcholine, a neurotransmitter required for muscle contraction and focus. Beta-alanine ­– Buffers blood acids to squeeze out more reps for better pumps and huge gains.
Nitrosigine – The world’s most effective form of arginine works synergistically with citrulline to maintain improved blood flow up to 3 hours. Coumabuterol Complex – 3 key ingredients work together for a comprehensive profile of adrenergic stimulation. Studies have shown that Citrulline Malate enhances exercise tolerance by reducing levels of blood ammonia and lactate that are typically elevated during strenuous exercise.
This ingredient will allow you to train with less rest in between sets and elevate your endurance capacity. A recent research study found individuals who consumed citrulline malate for 15 days were able to increase ATP production during exercise by 34% and improve phospho-creatine resynthesis after exercise by 20%. Arginine (NITROSIGINE) is a precursor to nitric oxide and expands blood vessels to optimize blood flow. These ingredients works in synergy to help increase the blood flow and the structural integrity of the artery walls. Preclinical data has shown that Nitrosigine is superior to standard arginine… with 2x the blood flow in vasodilatation response. Agmatine Sulfate helps improve nutrient partitioning which leads to an increase in muscle glycogen (carbs stored in muscle tissues) which then leads to more water retained WITHIN the muscle. Agmatine Sulfate also increases NO production by working as a competitive inhibitor of the enzyme NO Synthase. There are studies to suggest that the nutrient partitioning effects of agmatine sulfate are possibly due to its ability to increase the insulin response to carbohydrates. LH and GH levels have been shown to be increased through the effects of Agmatine Sulfate and its possible effects on the hypothalamus. Agmatine has also been shown to manipulate pain receptors which may allow you to train past normal pain thresholds. Beta-Alinine synthesizes to carnosine which helps keep your pH levels in check by absorbing positive hydrogen molecules (H+) that are produced during periods of heavy exercise. By combining magnesium to the creatine mixture in this compound – it allows (in a similar fashion to COP) the creatine to be absorbed and utilized for anabolic processes and prevents conversion to creatinine though the process of cyclization. Creatine MagnaPower pulls together both creatine and magnesium for the most effective ATP synthesis.
One of the biggest features of COP is that it has an extremely high level of absorption where as other forms of creatine can be broken down and destroyed through cyclization (a process by which creatine is often converted to creatinine – which, is useless for building muscles).
COP highly resists cyclization and is therefore one of the most bioavailable and effective creatine products on the market. In the body L-histidine combines with beta-alanine to form skeletal muscle carnosine; which plays a crucial role in hydrogen ion buffering and leads to improved exercise performance.
Recent research has shown that L-histidine may promote vasodilation and increase performances that require short, explosive bursts. Vanadyl sulfate has been shown to significantly improve glycemic control and there-by improve liver and muscle sensitivity to insulin.
Studies suggest that vanadyl sulfate helps muscle cells uptake glucose, and may help you perform better and recover faster. Choline improves structural integrity, signaling capacity and the fluidity of neural membranes. It has been shown that a dose of 500mg of Choline can boost focus, mood and concentration abilities. Although caffeine can affect a wide variety of motor and mental functions it is most commonly used to improve endurance exercise, focus and cognitive performance, and improve energy levels. According to the research higher doses of caffeine, in the 250-450mg range, are needed to provide an ergogenic benefit. This complex is combined with three of the most known and effective beta-1 and beta-2 adrenergic agonists. These agonists will boost your heart rate, create laser focus, and help utilize body fat from energy expended during your training. Best known as an alternative for ephedrine, Isopropylnoynephrine has several of the same benefits of ephedrine but not nearly the same side-effects. Isopropylnoynephrine can reduce appetite, increase alertness, burn fat, increase metabolism and increase energy. However, like ephedrine, if you take this too close to bedtime – it could create some insomnia.
A: To address your pre, intra, and post workout energy, muscle building, and recovery needs we suggest stacking PRE LEAN REVOLUTION with BCAA REVOLUTION and LEAN WHEY REVOLUTION.
7.L-arginine stimulation of glucose-induced insulin secretion through membrane depolarization and independent of nitric oxide. 1.Long-term glycine propionyl-l-carnitine supplemention and paradoxical effects on repeated anaerobic sprint performance.

2.Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects. 2.Effect of acute and short-term administration of vanadyl sulphate on insulin sensitivity in healthy active humans. Lifters have a certain appreciation for the enhancing effects of pre-workout supplements, but in some situations, you just need the focus and pump – none of the zip. Citrulline Malate – A dual-threat: Provides huge boosts to training volume and stimulates nitric oxide production. Norvaline – Inhibits the breakdown of Nitric Oxide to keep more of it active in the system. What makes NeuroVol special is that, along with the nitric oxide-induced, muscle-engorging pumps, we have included a Focal Matrix to help you attain great focus without any stimulatory ingredients. Arginine is a semi-essential amino acid and is a chemical precursor to nitric oxide (a blood vessel-widening agent). Arginine also triggers the body to make protein and has been studied for healing wounds, bodybuilding, and preventing tissue degradation in people with critical illnesses. Glycerol has also been shown to help athletes store extra water, delaying the need for hydration.
In addition, glycerol enhances plasma and intramuscular volume expansion, producing a more engorged muscular appearance. Ornithine when bound by salt at the molecular level is much more bio-available than its free form. Ornithine works in synergy with arginine in the metabolism of waste caused by intense exercise.
By increasing the nitric oxide production and decreasing waste you are able to train longer and decrease fatigue.
Norvaline works in conjunction with arginine and other nitric oxide precursors by extending or prolonging their activity. By prolonging this period more nitric oxide production can occur, even when the muscle cells supply of arginine starts to run low. One study has shown L-Norvaline can effectively increase the production of NO by as much as 60%. The main benefits of sodium bicarbonate supplementation is it can delay the onset of muscle fatigue and improve recovery from events requiring high-intensity bursts of anaerobic contractions of large muscle groups.
A: From a scientific perspective the “pump”, commonly referred to as hyperemia, supplies working muscles with oxygen rich blood and nutrients while also removing waste products such as carbon dioxide. A: We recommend stacking NeuroVol Revolution with any of our pre-workout products to promote optimal performance, focus, and pump. 7.E Morikawa, M A Moskowitz, Z Huang, T Yoshida, K Irikura and T Dalkara L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat. 8.S M Gardiner, A M Compton, T Bennett, R M Palmer, S Moncada Control of regional blood flow by endothelium-derived nitric oxide.
Pre-Lean was formulated to provide intense energy, laser-like focus, brute strength, and extended endurance to promote rippling, lean mass. Only Pre-Lean Revolution was built for detonating body fat while helping to drive lean mass adaptations and performance enhancement.
Nitric oxide is a vasodilator that can help to lower blood pressure and improve blood flow to both organs and muscles. Silicate is contained within the walls of the arteries to help maintain their structural integrity. This could be further explained by the increased blood flow to the muscle that occurs with increased NO production. Carnitine is crucial in muscle function by regulating energy flow across the cell membranes during strenuous activity.
Increasing Nitric Oxide helps blood flow to organs and muscles and optimizes oxygen and nutrient delivery to the muscles. Carnosine acts as an intra muscular buffer to keep the pH from dipping too low during a workout. By absorbing the H+ produced by strenuous exercise, your muscular pH levels are kept at an optimal level which will allow you to train harder and longer! Long-term CM supplementation appears to enhance the overall quality of training, leading to 5 to 15% greater gains in strength and performance. One is to strengthen the myelin sheath that coats nerve cells and will promote a better “mind muscle” connection.
It’s estimated that close to 90% of the population does not get the recommended amount of choline daily. Utilizing this effectively dosed compound, you will be able to focus on taking less rest or being distracted during you training. This has been shown to make caffeine anhydrous more potent because the body will absorb it more readily. A large review by the European Food Safety Authority concluded that a daily safe dose of 400mg is safe for adults.
Obviously, if you train after work, you don’t want your pre-workout to deprive you of all that anabolic sleep!

Don’t go without the best training sessions possible because your situation isn’t accommodating to stimulants, train with NeuroVol, and keep tearing up the gym.
This process vasodilates (enlarges) blood vessels and helps deliver more of the much needed oxygen rich blood and nutrients to working muscles in order to achieve the pump and ultimately muscle growth. When consumed glycerol is rapidly absorbed primarily in the small intestine, distributed equally among all fluid compartments, and promotes hyperhydration by inducing an osmotic gradient. This suggests improved efficiency in exercise, thermoregulation and decreased physiological stress.
In every serving, you will get an effective dose of intense muscle pumping agents, metabolism boosting ingredients, and all the mind-muscle connection that your body can handle! Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Role of histidine-related compounds as intracellular proton buffering constituents in vertebrate muscle. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. NeuroVol is a stimulant-free, effectively-dosed pre-workout designed to help you crush the iron without any jittery aftershocks. Since valine is an essential amino acid, L-Norvaline has to be obtained through the diet or supplementation, as the body cannot produce it. Dietary L-arginine supplementation increases muscle gain and reduces body fat mass in growing-finishing pigs. Ultraviolet A induces transport of compatible organic osmolytes in human dermal fibroblasts.
L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism.
Sodium bicarbonate can be used as an ergogenic aid in high-intensity, competitive cycle ergometry of 1 h duration. Acute effects of a caffeine-taurine energy drink on repeated sprint performance of American college football players.
Effects of 28 days of resistance exercise and consuming a commercially available pre-workout supplement, NO-Shotgun®, on body composition, muscle strength and mass, markers of satellite cell activation, and clinical safety markers in males. The role of histidine-proline-rich glycoprotein as zinc chaperone for skeletal muscle AMP deaminase.
Central Nervous System Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Central Nervous System Agents), 12(2), 82-94.
Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs. Effects of caffeine, sodium bicarbonate, and their combined ingestion on high-intensity cycling performance.
However, you should expect to see big improvements in strength, power, and endurance after taking creatine.
A clinical evaluation to determine the safety, pharmacokinetics, and pharmacodynamics of an inositol-stabilized arginine silicate dietary supplement in healthy adult males.
An Open?label, Dose?escalating Study Followed by a Randomized, Double?blind, Placebo?controlled Trial.
Oral creatine monohydrate supplementation improves brain performance: a double–blind, placebo–controlled, cross–over trial.
Effect of glycerol-induced hyperhydration on thermoregulatory and cardiovascular functions and endurance performance during prolonged cycling in a 25 C environment.
Effects of ?-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women. Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats. Effects of glycerol-induced hyperhydration prior to exercise in the heat on sweating and core temperature.
Effect of different frequencies of creatine supplementation on muscle size and strength in young adults. Creatine supplementation reduces muscle inosine monophosphate during endurance exercise in humans.
Effects of 8 weeks of Xpand (R) 2X pre workout supplementation on skeletal muscle hypertrophy, lean body mass, and strength in resistance trained males. Studies of histidine as a suitable isoelectric buffer for tryptic digestion and isoelectric trapping fractionation followed by capillary electrophoresis–mass spectrometry for proteomic analysis. The effects of six weeks of supplementation with multi-ingredient performance supplements and resistance training on anabolic hormones, body composition, strength, and power in resistance-trained men.
Effects of ?-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. Alteration of taurine homeostasis in acute heatstroke.Critical care medicine, 21(4), 551-554.

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