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admin | Diet Pills | 29.01.2016
More doctors than ever are prescribing antidepressants and anti-anxiety drugs for patients who aren’t suffering from mental health issues. Antidepressants are few types of medication which is usually used for depression treatment. It is important to mention that anti-depressants were used for decades and all accumulated information show that treatment only with antidepressants cannot be fully effective – special changes in lifestyle are always needed. Before you start using anti-depressants, you need to know proper information including benefits, risk factors and side effects of antidepressants. According to several studies, the main cause of depression is the deficit of neurotransmitters (chemical messengers) in the brain (such as serotonin, norepinephrine and dopamine). Scientists discovered that in many cases the depression is caused by imbalance of certain neurotransmitters (chemical messengers) in the brain, such as serotonin, norepinephrine and dopamine. Examples of tricyclic antidepressants – Imipramine (Tofranil), Amitriptylin, Desipramine (Norpramin). This type of antidepressants are considered as a modern medication for depression treatment – this antidepressants block selectively the re uptake of serotonin.
Examples of antidepressants with selective Serotonin re uptake – Clomiprimine, Fluoxetine (Prozac), Sertraline, Paroxetine. This type of antidepressants triggers the oxidative deamination of norephinephrine, serotonin, and other amines – this oxidation cause reduced levels of neurotransmitter and increased levels of norepinephrine which in turn causes a stimulation effect.
This type of antidepressants is not very effective and, at the same time, they have several side effects.
As causes of depression are not very clear, it is not very clear how and why sometimes antidepressants are effective and sometimes not really. In most cases anti-depressants’ side effects are short-term but there is a list of side effects mentioned by clients who used medication for depression treatment. Some anti-depressants’ side effects disappear after the first few weeks but sometimes side effects could get worse for long period. Medical professionals noted increased risk of suicide attempts in clients who use anti-depressants.

Billy Joel has gone through some personal struggles in the past, entering rehab for substance abuse in 2002 and 2005 after battling depression for years. Referring to his three car accidents before he entered treatment, the 64-year-old singer tells the New York Times that depression led to his reckless driving -- not alcohol.
Joel may be talking about his relationship with Katie Lee, whom he wed in 2004 -- when she was just 23 -- before ending their marriage in 2009. After years of struggling with cocaine and heroin addiction and serving jail time, the actor is clean and sober. In fact, the choice of medication is often a trial and error experiment.The excruciating and disabling nature of depression highlights the urgency of developing treatments that act more rapidly. Antidepressants are used for restoring mentally depressed clients – antidepressants can improve the mental status of most depressed women. Informed means armed – you can make your personal decision about antidepressants only if you are correctly informed.
Scientists discovered deficit of norepinephrine at receptors in the brain in clients with depression.
Thanks to this type of antidepressants the level of serotonin is increasing in the central nervous system. Ketamine, a drug used in general medicine as an anesthetic, has recently been shown to produce improvements in depressed patients within hours of administration.
Antidepressant medication is used by mental health professional for controlling and managing depression symptoms. Antidepressants are designed to increase the concentration of neurotransmitters at receptors level in the brain.
It is very important to fight the main cause of depression – stressful life, unhealthy relationship, social pressure, abuse (psychological or physical), unhealthy lifestyle, etc. The suicide risk is particularly great during the first one to two months of treatment with anti-depressant.
A new study being published in the journal Biological Psychiatry provides some new insight into the mechanisms by which ketamine exerts its effects.Ketamine is classified as an N-methyl d-aspartate (NMDA) glutamate receptor antagonist.

It is pretty strong medication which can be used only under professional guidance of your doctor. Maeng and colleagues now provide new evidence that these antidepressant effects of NMDA receptor antagonists are mediated by their ability to increase the stimulation of a-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) glutamate receptors.In other words, their findings indicate that the antidepressant-like effects of drugs like ketamine are dependent on AMPA receptor stimulation. Some antidepressants (amphetamines, electroconvulsives) increase the release of neurotransmitters (norepinephrine), others (monoamine oxidase inhibitors – MAO inhibitors) just prevent inactivation of neurotransmitters and the third type of antidepressants prevent the re uptake of neurotransmitters. This is important because depression in Parkinson’s disease is under-recognized, underappreciated and undertreated. This suggests that drugs that enhance AMPA receptor function might have rapid antidepressant properties.Dr. Husseini Manji, corresponding author on this paper and a Deputy Editor of Biological Psychiatry, explains that “by aiming new medications at more direct molecular targets, such as NMDA or AMPA, we may be able to bypass some of the steps through which current antidepressants indirectly exert their effects — a roundabout route that accounts for the long time it takes for patients to begin feeling better with the conventional medications.”He adds, “Today’s antidepressant medications eventually end up doing the same thing, but they go about it the long way around, with a lot of biochemical steps that take time. Now we’ve shown what the key targets are and that we can get at them rapidly.”This study is especially important because even though this important antidepressant effect has been found in ketamine, its use also has significant drawbacks. Rick Nauert has over 25 years experience in clinical, administrative and academic healthcare. He is currently an associate professor for Rocky Mountain University of Health Professionals doctoral program in health promotion and wellness. Nauert began his career as a clinical physical therapist and served as a regional manager for a publicly traded multidisciplinary rehabilitation agency for 12 years. He has masters degrees in health-fitness management and healthcare administration and a doctoral degree from The University of Texas at Austin focused on health care informatics, health administration, health education and health policy.
His research efforts included the area of telehealth with a specialty in disease management.

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