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24.09.2014

Tinnitus treatment vagus nerve, high blood pressure and sleeping alot - Within Minutes

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Tinnitus impacts over 50 million Americans, nearly two million of which classify the phantom whistling, buzzing, or whining sounds as debilitating.
VNS involves sending a mild electrical signal through the vagus nerve and has been used for treating other conditions such as depression and stroke. The positive effects of VNS therapy were shown to still be significant two months after treatment. Tinnitus is a debilitating condition thought to be caused by the brain generating a signal in areas no longer stimulated by the auditory system.
The Serenity System couples an implantable vagus nerve stimulator with a tone generator that plays sounds of various frequencies while electric signals are delivered by the neurostimulator.
The cranial nerves reside mostly in the head region and control much of what goes on in the face and neck. Besides output to the various organs in the body, the vagus nerve conveys sensory information about the state of the body’s organs to the central nervous system.
Stimulating the vagus nerve through electrical impulses causes the release of neurotransmitters and elevated levels of the inhibitory neurotransmitter GABA, which reduces heart rate, controls epileptic seizures and alters mood patterns. For instance, when someone is exposed to a stressful event, a hormone called epinephrine is released into the bloodstream, which activates the vagus nerve. Because the vagus nerve is associated with many different functions and brain regions, research is being done to determine its usefulness in treating other illnesses, including various anxiety disorders, Alzheimer’s disease, migraines, fibromyalgia, and, as we shall soon investigate, tinnitus.
Investigators at UT Dallas also investigated the ability of VNS to stimulate cortical reorganization to restore neuronal activity to normal and reverse tinnitus in laboratory rats. The theory behind VNS for tinnitus is as follows: When one neuron sends a signal to another neuron in the brain, it is typically referred to as a ‘spike’. By consistently pairing VNS with all other tones except the tinnitus tone, the other neuron groups expand and the tinnitus tone neurons shrink. Assessments were made using standard tinnitus questionnaires and a measure called minimum masking level (MML).
While the promise of VNS for tinnitus is great, there is a lot of work to be accomplished before it can become a widespread, effective therapy.


There are significant, though not life-threatening, side effects of the therapy, which has been used on about 50,000 people for severe epilepsy and treatment resistant depression. Researchers are gearing up for a clinical trial designed to evaluate the effectiveness of a novel tinnitus therapy developed at UT Dallas. The therapeutic approach developed at UT Dallas combines audible tones with brief pulses of electrical stimulation to the vagus nerve in the neck. The tinnitus research is a collaboration among the Texas Biomedical Device Center, Communication Technology Center, Callier Center for Communication Disorders, UT Southwestern Medical Center and MicroTransponder, a bioengineering firm.
No cure exists for tinnitus, but new treatments are being discovered that show huge promise.
Stimulating the vagus nerve releases chemicals involved in neuroplasticity, so doing so while playing the tones will hopefully train the brain to correlate the various sound frequencies to their normal areas in the auditory cortex.
But the vagus nerve, also known as the tenth cranial nerve, influences the body and brain more than most. Eighty to ninety percent of the nerve fibers in the vagus nerve are sensory nerves communicating the state of the body and digestion to the brain. The nerve then sends a signal to the brain to release the neurotransmitter norepinephrine, which assigns extra neurons and strengthens memory storage for emotional feelings of that specific time.
There is not an audiological device in the world that can measure and quantify tinnitus without the subject being able to communicate with the doctor, and rats can’t speak!” This led to the writing of a previous article on “An Animal Model of Tinnitus”.
During the study, patients sat in a comfortable chair and wore headphones, listening to tones while receiving small bursts of neurostimulation, which activated the vagus nerve.
It is also important to note that VNS, while FDA approved for treating depression and seizures, is not FDA approved for treating tinnitus and remains in clinical trials. Repeatedly pairing vagus nerve stimulation with a movement reorganizes primary motor cortex.
The results of trials on this treatment, according to an article on Science Daily show "Half of the participants demonstrated large decreases in their tinnitus symptoms, with three of them showing a 44-percent reduction in the impact of tinnitus on their daily lives." Vagus nerve stimulation to treat tinnitus is combined with auditory tones in order to be effective. There are a number of branching nerves that come in contact with the heart, lungs, larynx, stomach and ears.


Pairing several of these tones (except the tinnitus tone) helped subdue the abnormal hyperactivity and restored the auditory cortex activity back to normal in a rat model of tinnitus.
Clinical applications of his research revolve around evaluation of individuals suspected of having auditory perceptual problems linked to the central nervous system, conditions known as auditory processing disorders. He has served on key panels of the American Academy of Otolaryngology-Head and Neck Surgery and has investigated the causes of and best treatments for a wide variety of ear-related medical problems. There are other successful therapies such as Neuromonics that use tonal therapy to achieve relief from tinnitus. Electrical stimulation of the vagus nerve has been shown to be helpful for chronic depression and in controlling seizures in people with intractable epilepsy. In the tinnitus brain, however, the neurons at the tinnitus frequency are highly excitable. This lack of input can result in changes to the auditory system, which is believed to be responsible for some forms of tinnitus.
Understanding how it adapts to new situations could help in developing new treatments for disorders such as tinnitus, autism and stroke. New research shows this same stimulation, coupled with sound therapy, has the potential to reduce noise levels in those with tinnitus. Hundreds of thousands of nearby neurons fire simultaneously in the tinnitus frequency whether there is outside stimulus or not. This simultaneous firing of brain cells is referred to as synchrony, which is thought to be one of the mechanisms responsible for sounds perceived by tinnitus patients.



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Comments to “Tinnitus treatment vagus nerve”

  1. AnGeL:
    Other possible causes such as teeth grinding and clenching , osteoarthritis.
  2. RAMMSTEIN:
    Exposure to loud noise can deplete your body of magnesium and can psychiatric disorders that must be considered.