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Sleep deprivation cures depression, tinnitus specialist washington dc - .

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For those of us who chronically seem to work and play too hard and deprive ourselves of sleep, it may be difficult to believe that sleep deprivation can have benefits. Figure 1  Therapeutic effect of sleep deprivation The effect of sleep deprivation on a profile of symptoms in patients with unipolar depression. Figure 2  Effects of sleep deprivation on mood rating for two groups of patients Notice that individuals who respond to sleep deprivation with reduced depression rating scores (responders) return to their previous condition after one night of sleep.
A more practical approach uses partial sleep deprivation, especially effective during the second half of the night, or sleep phase shifting.
But according to a summary of results compiled from 61 studies completed over 20 years, involving more than 1700 individuals with depression, total sleep deprivation significantly reduced depressive symptoms in 59% of the patients (Wu and Bunney, 1990). The difference between the two curves represents changes in symptom severity before (the upper profile line) and after (the lower profile line) 24 hours of sleep deprivation.

However, the fact that most of the classical antidepressant drugs affect circadian rhythms, especially sleep, supports the argument that sleep may be critical to mood changes in depressed patients.
The most consistent effects involve the correction of REM sleep abnormalities characteristic of depressed individuals.
It may be worth noting that the patients who responded to sleep deprivation were those who did not show the normal hormonal response to dexamethasone. For example, following a single night of wake therapy, sleep phase advance with a 5-day gradual return to normal sleep time prevented relapse in two-thirds of wake therapy responders. Of course, since sleep is regulated by synergistic actions of several neurotransmitter systems, the sleep therapies and antidepressant drug therapies may have similar neurochemical targets. An additional benefit is that when classic antidepressant medication is used along with partial sleep deprivation, depressed patients respond more quickly than they do using the antidepressant drugs alone or using partial sleep deprivation alone.

Unfortunately, the depressive symptoms returned following a single night of sleep (Figure 2) for most individuals who were responders. However while 83% of the patients not receiving medication relapsed after one night’s sleep, only 59% of those given antidepressant medication relapsed after sleeping.

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Comments to “Sleep deprivation cures depression”

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  4. DozanQurdu:
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