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03.03.2015

Chronic fatigue causes, pain ear ringing - Test Out

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Researchers seeking to uncover the cause of chronic fatigue syndrome are back to square one after a once-promising theory that linked mouse viruses to the condition has been dismissed. The once-promising belief that 2 retroviruses that cause leukemia in mice are potential causes of chronic fatigue syndrome in humans has been dismissed by findings from the most rigorous study to date on the link. Chronic fatigue syndrome is a disabling disorder characterized by persistent unexplained fatigue in association with impaired memory or cognition, muscle or joint pain, headache, sore throat, tender lymph nodes, and night sweats. In the mBio study, researchers (including some who worked on the original Science and PNAS studies) recruited 147 patients with chronic fatigue syndrome and 146 matched controls from 6 sites across the United States. When a person experiences extreme tiredness that isn’t alleviated by rest or sleep, that person may very well have Chronic Fatigue Syndrome, or CFS.
What distinguishes CFS from other disorders is that fatigue is present for a period of 6 months or longer, and the patient will report other symptoms such as headaches, muscle pain, memory problems and decreased mental concentration, multiple joint pain, inability to sleep well, a sore throat, and swollen lymph nodes. Any mode of activity, whether physical or mental, that a patient undertakes is also known to prolong the incidence of fatigue for more than 24 hours at a time.
Despite CFS research that has been ongoing for nearly 20 years, there is yet no evidence found of the causes of Chronic Fatigue Syndrome.
Chronic Fatigue Syndrome usually affects four times more women than men, generally between the ages of 40 and 50, although it may also afflict individuals of all ages, genders, ethnicities, or socioeconomic groups. Diagnosing Chronic Fatigue Syndrome has proved to be a very challenging dilemma for the medical community. There has been a huge amount of debate surrounding the issue of how to properly diagnose Chronic Fatigue Syndrome.
The doctor will have to determine if the patient suffers from chronic insomnia, or barring that, constant non-restful sleep.


There is no definite cure or therapy for Chronic Fatigue Syndrome, and the best that the medical community can offer is to treat the various symptoms of this disorder, such as the all-encompassing fatigue and sleep problems, to enable patients to lead normal lives. The sooner Chronic Fatigue Syndrome is diagnosed and treated, the better the chances are of recovery. Chronic fatigue syndrome is a condition of prolonged and severe tiredness or weariness that is not relieved by rest and is not directly caused by other conditions.
Relaxation and stress-reduction techniques can be helpful in managing chronic pain and fatigue. In the study, published today in mBio, researchers found no evidence of infection with either xenotropic murine leukemia virus–related virus (XMRV) or polytropic murine leukemia virus (pMLV) infection in 147 patients with chronic fatigue syndrome. An explanation, proposed in a 2009 article published in Science that linked XMRV to the syndrome, gave hope to those with the condition that it might be treated with drugs that are used to treat HIV, another infection cause by a retrovirus.
This type of illness makes sufferers feel constantly fatigued on a day-to-day basis, despite periods of rest or sleep. Both debilitating and complex, no amount of bed rest will improve the fatigue experienced by patients who have CFS. People who have been diagnosed with Chronic Fatigue Syndrome will notice that the symptoms they experience are rather similar to that of various other disorders. Other symptoms that point toward a diagnosis of Chronic Fatigue Syndrome will usually include persistent muscle pain, multiple joint pain with the absence of redness or swelling, tender lymph nodes, a sore throat, and headaches that vary in length and severity. Seek care first from the health care provider who knows you best and will work with you to rule out other possible causes of symptoms and identify other conditions. While a single cause for CFS may yet be identified, another possibility is that CFS represents a common endpoint of disease resulting from multiple causes.


Typically, the fatigue develops suddenly, often following an infection such as upper respiratory infection or mononucleosis.
Another study, published in early 2010 in the Proceedings of the National Academy of Sciences (PNAS), reported detecting pMLV in patients with chronic fatigue syndrome, which further bolstered the theory that the condition might be caused by a mouse virus. Blood samples from those with chronic fatigue syndrome and the control group were collected for blinded analysis of XMRV, pMLV, or both using molecular, culture, and serological methods. The nature of these various symptoms have often stymied doctors from distinguishing Chronic Fatigue Syndrome compared to a host of other ailments with similar symptoms. People who suffer from Chronic Fatigue Syndrome are most often listless, unable to function properly, and perform everyday activities at a very low-key level compared to what they were able to accomplish before their illness.
The symptom of unyielding fatigue is non-specific and often similar to hundreds of other ailments, making CFS a difficult disorder to diagnose. Further, Chronic Fatigue Syndrome is a type of disorder that occurs intermittently, with patients frequently relapsing in no predictable manner.
After the initial illness gets better, you are left with overwhelming fatigue and a number of additional symptoms. But the inability of other laboratories and the original researchers to replicate the XMRV or pMLV association with chronic fatigue syndrome lead to the Science article being retracted in December 2011.



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Comments to “Chronic fatigue causes”

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