Restless legs syndrome (RLS) is a disorder that affects more than 5 million adults in the United States, according to the National Institute of Neurological Disorders and Stroke (NINDS). Typically, the sensations appear when an individual is trying to relax, or sitting for long periods.
The most common type of restless legs syndrome, called primary RLS, often runs in families, according to the National Sleep Foundation. The patient has strong and irresistible urges to move his legs and uncomfortable sensations that often accompany the urges.

The Willis-Ekbom Disease Foundation (formerly the Restless Leg Syndrome Foundation) provides answers to frequently asked questions, information about treatment options and access to support groups. The Johns Hopkins Center for Restless Legs Syndrome conducts research, provides training and information, and supports other programs on the cause, diagnosis, prevention and treatment of restless legs syndrome.
Signs of this disorder are quick movements of the legs every 20 to 40 seconds during the night. Researchers have found an RLS gene, which was shown to account for about half of RLS cases.

A general practitioner also may refer patients to a sleep specialist for an overnight examination. For example, velvet-bean extracts provide a natural compound called L-dopa, which converts into dopamine.

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