Welch then prepared stereoisomers of this compound, which were tested in vivo by animal behavioral scientist Albert Weissman.
Individuals who are allergic to acamprosate, or those who have severe case of kidney ailment should not use Aotal. Users must tell their physicians of the number of alcoholic beverages they consume while they are taking Aotal.

However women who are pregnant or planning to get pregnant should tell their doctors about their condition and plans before agreeing to take Aotal.
It is important that users immediately inform their physicians of having suicidal thoughts or being depressed while taking Aotal.

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