Melatonin (Controlled Release)Melatonin is a neurohormone produced from tryptophan by the pineal gland when it is stimulated by darkness. Research has shown that melatonin not only fights free radicals during sleep, but also stimulates the body’s own antioxidant systems.
A decrease in plasma melatonin correlates with a decline in immune function in some individuals beginning around the age of sixty.
The biphasic delivery system consists of 1mg of melatonin in the coating solution and the remainder in the tablet core.

Melatonin inhibits oxidative modification of low-density lipoprotein particles in normolipidemic post-menopausal women.
Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and noncognitive functions in Alzheimer type dementia. Serum melatonin kinetics and long-term melatonin treatment for sleep disorders in Rett syndrome.
Melatonin and melatonin-progestin combinations alter pituitary-ovarian function in women and can inhibit ovulation.

Effect of melatonin on estrogen and progesterone receptors in relation to uterine contraction in rats. This gel layer acts as a diffusion barrier to control the rate of release of the melatonin in the tablet core.

Restless leg syndrome cure
Seizure in child while sleeping

Comments Melatonin release is controlled by

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