11.11.2015

Chances of pregnancy at age 49

One of the implications that many people take away from these results is that society should aid those who wish to have children at later ages.
The General Social Survey has a variable, AGEKDBRN, which asks respondents when their first child was born. All the x-axes on the plots are age of the mother when the first child was born, while the y-axes are proportions across classes. This is very interesting, but it doesn’t seem to control for the age of aspiring fathers. I was always curious about differentials in newborn problems (both developmental and genetic) between mother and father ages. Razib is basically right, the time to pregnancy doesn’t change much for men from age 30 to 40.
Although some studies show contradicting results, we conclude that increasing paternal age is associated with reduced fertility, at least in couples where men are older than 40 years and women are at least 35 years. Having made the exciting decision to start your own family you are sure to be wondering how long it will take to get pregnant.
You may find it encouraging knowing that the number of women over the age of 30 having babies has risen in recent decades (ONS 2010) .
Most women will be able to conceive naturally and give birth to a healthy baby if they get pregnant at 35 years old.
The average age at which women have in vitro fertilisation (IVF) treatment in the UK is rising.
While many men remain fertile into their 50s and beyond, the proportion of men with sperm disorders increases with age (RCOG 2011).
About half of the women who don't get pregnant in the first year conceive during the following year, giving a pregnancy rate of 92 per cent within two years.
Figures for women aged 30 to 34 and aged 35 to 39 are fairly similar, with 94 per cent and 90 per cent conceiving within two years, respectively (NCCWCH 2013: 65). As a woman ages it is more likely that she may have had longer exposure to a condition that has not been treated.


Age aside, there are some steps you can take to give yourself the best possible chance of conceiving and having a healthy pregnancy. Learn more about getting pregnant in your 20s, 30s or 40s, or get tips, advice and support in our friendly community of mums and mums-to-be. Join now to receive free weekly newsletters tracking your baby’s development and yours throughout your pregnancy.
3) In anovulatory infertile women, failure to achieve pregnancy after three to six cycles of successful ovulation induction should be viewed as an indication to perform additional diagnostic evaluation or, if evaluation is complete, to consider alternative treatments. 7) Age is a better predictor of diminished ovarian reserve than FSH.  A 45 year old will have a reduced fertility potential even if her FSH level is normal.
9) An elevated FSH level does predict the chance of pregnancy.  However, it does not predict ovarian response to fertility drugs. If your day-3 FSH level is elevated, the next step is to have a discussion with your physician.  A combination of age, FSH, E2, AMH level, antral follicle count, weight and previous ovarian response will probably used to estimate your chances of success. The ideal time to freeze your eggs is before the egg quality decreases (generally before age 38).
8) AMH levels are NOT influenced by birth control pills, pregnancy or by GnRH agonists (e.g. The chances of cycle cancellation, spontaneous miscarriage, ectopic pregnancy or multiple births were not significantly different. Fertility also declines in men, and I would estimate that as women age so do their partners, multiplying the chances of infertility further.
You know the most fertile years are in your 20s, but want to get a better idea of how age affects your fertility. Fertility starts to decline for women from about the age of 30, dropping down more steeply from the age of 35 (CKS 2007, NCCWCH 2013:65). Even though male fertility also declines with age (RCOG 2011, Utting and Bewley 2011), it tends to happen gradually for men. For some women having a multiple pregnancy brings them their dream family in one pregnancy.


But if you are over 35, and finding that positive pregnancy test elusive, it is important to seek help sooner rather than later (NCCWCH 2013:6). Plus the probability of gestation-related problems probably increases significantly with age. As women grow older the likelihood of getting pregnant falls while the likelihood of infertility rises. By the age of 40 only two in five of those who wish to have a baby will be able to do so (RCOG 2011). This could prevent fertilisation altogether or increase the likelihood of an ectopic pregnancy (CKS 2007, NCCWCH 2013:129, Utting and Bewley 2011). The paradox of declining fertility but increasing twinning rates with advancing maternal age. Does this mean age has something to do with my situation or You suggest I start seeking professional help. Anti-mullaerian hormone level are also routinely used (details in another blog),  Ultrasound measurement of ovarian volume and antral follicle count, patients age and weight (Body mass Index, BMI is discussed in another blog) are combined to assess ovarian reserve.
I  found a pregnancy probability calculator online which I cross-validated with some of the literature. By the time you are forty-five years old, your chance of conceiving with your own eggs is about 1%. It allows your ‘older and wiser’ self the opportunity to use your own (instead of relying on donor eggs) eggs, while keeping the likelihood of pregnancy at that of your “younger” self. There is no “undoing” or reversing age related infertility, it is simply a natural process that the eggs go through, whether we are ready or not.



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