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The symptoms can often stop and then start again, and sometimes they can appear unrelated to your diet and digestive symptoms. In Mild cases of Coeliac disease their are no noticeable symptoms and the condition is often only detected during testing for another condition.
Severe Coeliac disease leads to the characteristic symptoms of pale, loose and greasy stool nd weight loss or failure to gain weight particuraly in young children). Coeliac disease is an autoimmune condition caused by an abnormal immune reaction to the protein gluten, refer to our Can and Can’t page for examples.
Autoimmune conditions cause your immune system to mistake healthy cells and substances for harmful ones and produce antibodies against them.
In the case of Coeliac disease your immune system mistakes one of the substances that makes up gluten called gliadin as a threat to the body. The surface of the intestine is usually covered with millions of tiny tube-shaped growths called villi. As a result, your intestine is no longer able to digest nutrients from your food which leads to the symptoms of coeliac disease such as diarrhoea and weight loss. Routine screening for Coeliac disease is not recommended unless you have symptoms or are at an increased risk of developing them. In 2009, the National Institute for Health and Clinical Excellence (NICE) issued guidance about when testing for coeliac disease should be carried out.
Your GP will take a blood sample and test it for antibodies usually present in the bloodstream of people with coeliac disease. If coeliac disease antibodies are found in your blood, your GP will refer you for a biopsy of your gut.
However, it is sometimes possible to have coeliac disease and not have these antibodies in your blood.

If you need to have a biopsy, an endoscope (a thin, flexible tube with a light) will be inserted into your mouth and gently passed down to your small intestine. Before the procedure, you will be given a local anaesthetic to numb your throat or a sedative to help you relax. The gastroenterologist will pass a tiny biopsy tool in through the endoscopy to take tiny samples of the lining of your small intestine. If you are diagnosed with coeliac disease, you may also have other tests to assess how the condition has affected you so far.
You may have further blood tests to check levels of iron and other vitamins and minerals in your blood. If you appear to have dermatitis herpetiformis (an itchy rash that is also caused by gluten intolerance), you may have a skin biopsy to confirm it. This is carried out under local anaesthetic where a small skin sample is taken from the area so it can be examined under a microscopic. Coeliac disease is usually treated by simply excluding foods that contain gluten from your diet. This prevents damage to the lining of your intestines (gut) that is caused by gluten, and the associated symptoms, such as diarrhoea and stomach pain. If you have coeliac disease, you must give up all sources of gluten for life because eating foods that contain it will cause your symptoms to return and cause long term damage to your health.
When you are first diagnosed with coeliac disease, you will be referred to a dietitian to help you adjust to your new diet without gluten. If you have coeliac disease, you will no longer be able to eat foods that contain wheat, barley or rye. Even if you only consume a small amount of gluten such as a piece of toast, you may have very unpleasant intestinal symptoms. Many basic foods, such as meat, vegetables, cheese, potatoes and rice, are naturally free from gluten so you can still include them in your diet.
Coeliac disease, is a disease in which the body becomes intolerant to gluten, which is focused in the gliadin.

The gliadin proteins have the ability to activate the disease in the person through the amino acid sequence found in the gliadin. The main treatment for coeliac disease is a gluten free diet in which the diseased person does not ingest any gluten, and specifically gliadin. It's completely burning intestinal pain under arms and legintestinal muscle spasm medicationcause of muscle spasms in intestinesresin terracotta warriors statue for sale flaxseed blocked intestineintestines picturesymptoms diarrhea vomiting spasms noisy intestinesis small intestine bacterial overgrowth connected to bacterial vaginosislifespan for a feline with intestinal cancerthe use of parade apple cidar vinegar for injured big intestine during surgical operationbob intestinal upsetfree of charge to use our service. Gliadins and glutenins are the two main components of the gluten fraction of the wheat seed. You should not be avoiding gluten from your diet when the blood test is done as this could lead to an inaccurate result. So if you continue to have Coeliac disease-like symptoms despite having a negative blood test your GP may still recommend you have a biopsy.
This will help determine whether coeliac disease has led to you developing anaemia (a lack of iron in your blood) due to poor digestion. This may sound daunting, but your GP can give you help and advice about ways to manage your diet.
If you keep consuming gluten regularly, you will also be at greater risk of osteoporosis and cancer in later life. Many gluten-free alternatives are widely available in supermarkets and health food shops, including pasta, pizza bases and bread.
There have been searches for an affordable and much better treatment, but the main treatment remains to abstain from ingesting any gluten. However, in coeliac disease, the damage and inflammation to the lining of your gut flattens the villi, which reduces their ability to help with digestion.

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