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January 28, 2015BIMUNO PRe-bioticAnxiety, Bifidobacteria, Bimuno, Bimuno Feeds Good Gut Bacteria, C diff & Anxiety, C. I was looking for a non-pharmaceutical way to help my anxious and OCD patients so asked my supplements guru, David Miller, MD at LifeThyme (a health food store in NYC). It comes as sachets of tasteless powder to sprinkle over food or add to drinks and also as soft chewable pastilles. Bimuno® is a new PREbiotic product that feeds the good, PRObiotic bacteria living in our guts (such as Lactobacilli and Bifidobacteria) to the detriment of the bad bacteria (pathogens). PREBIOTICS are specialized plant fibers containing complex sugars (such as inulin,  fructo-ogliosaccharides and galacto-oligosaccharides) that are indigestible by humans but promote the growth of beneficial bacteria (PROBIOTICS) living in our gut microbiomes by serving as food for them.
PROBIOTICS are helpful, live bacteria and yeasts our bodies need to function and maintain good health.
Sometimes PREBIOTICS and PROBIOTICS are combined in the same supplements, called SYNBIOTICS. See my earlier posts Prebiotics and Probiotics and  PREbiotics and PREbiotics for more information. It selectively boosts Bifidobacteria which play a key role in immune function and maintaining and building a healthy digestive system. Bimuno is the result of many years of intensive research by a team of international digestive health experts and the University of Reading. Bimuno® original powder is the natural way to increase and energise your good gut bacteria helping you to manage your gut health.  Bimuno works in a similar way to prebiotics naturally found in human breast milk which promote a healthy bacterial balance within the gut. Scientific studies indicate that the unique second generation Galacto-oligosaccharide formulation of Bimuno powder, can help to encourage and sustain a healthy level of your friendly gut bacteria(Bifidobacteria).
Published scientific studies have shown that, with daily use, the majority of Bimuno users experience a significant increase in their gut Bifidobacterium within just 7 days.
This in itself is impressive but by a unique anti-adhesive action it also helps flush ‘bad’ bacteria from your gut at the same time for a healthy microflora balance. Christian John Lillis, of the Peggy Lillis Foundation, reports noticing an uptick in the number of people on Clostridium difficile Facebook groups who mention that they’re also struggling with anxiety. Animal studies have previously shown a link between mood and brain function and probiotics in the gut microbiota.
Now new research on healthy human adults conducted by a group of neurobiologists at Oxford University demonstrated that supplementation with PREbiotics (Bimuno® galacto-oligosaccharides, B-GOS) lowered the subjects’ neuro-endocrine stress responses and increased their ability to  process positive versus negative attentional vigilance. The researchers assessed how subjects processed emotional information, such as positively and negatively charged words, after they’d been taking the prebiotic supplement. A similar effect has been observed in people taking anti-depressants and anti-anxiety pharmaceutical medication.
The galacto-oligosaccharides in Bimuno® are a mixture of disaccharides, trisaccharides, a tetrasaccharide and a pentasaccharide. DISCLAIMER:  Nothing on this site or blog is intended to provide medical advice, diagnosis or treatment. In general I am wary of websites that present research about their specific product as being helpful without presenting other studies comparing to other companies products or to levels in known other sources of the stuff. The article you site mentions three types of prebiotics occurring naturally in foods: Inulins, Fructo-oligosaccharides (FOS), and Galacto-oligosaccharides (GOS).


Here’s a list of research studies that led to the development of Bimuno with the particular type of galacto-oligosaccharides found in it. Our results have provided the necessary ‘proof-of-principle’ for the central actions of prebiotic consumption. BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels? Sorry, but eating prebiotic foods, while the intention is good, the results don’t equate.
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If you have a C diff infection in your bowel, it means that your body is waging a war with the clostridium difficile bacteria. Chances are that you recently had a dose of antibiotics as C difficile colitis is almost always preceded by antibiotic therapy. Occasionally a nefarious pathogen like clostridium difficile can get into your colon and cause some real damage and discomfort if it finds the environment favourable enough to grow rapidly. Read about the two factors that must be present for a C diff infection to take hold and flourish in your colon.
Okay so let's suppose you have the unfortunate experience of being vulnerable to contracting clostridium difficile.
Abdominal cramps and tenderness - stomach cramps and diarrhea usually occur together when colon inflammation is present.
Nausea and loss of appetite - who wants to eat when every mouthful sends you to the bathroom with cramps and diarrhea? Fever - a mild temperature may not even be noticed, but this is your body's response to the interaction with this pathogen and its attempts to get rid of it. These symptoms can be mild or severe depending on a variety of individual factors like your current state of health, the degree of intestinal dysbiosis that is present, and how well your immune system functions. In severe cases bloody diarrhea may be present and if the infection is protracted and not responding to treatment, weight loss is inevitable. Unfortunately they do not work for all cases all the time and they certainly contribute to ongoing intestinal dysbiosis as they kill off not only the nefarious clostridium difficile bacteria but all the good ones you need as well. Well informed physicians would always recommend that you protect your colon health by taking probiotics after a course of antibiotics, and this might be the most beneficial thing to do, however, it does take a long time to build up the numbers of beneficial bacteria again using supplements. I just ordered some (the pastilles) to try myself – especially to use during travels outside the country, which often lead to upsets in my gut microbiome.
They are found in fermented foods such as kefir, live-culture yogurt, real sauerkraut and pickles (not ones made with vinegar), kimchi, kombucha and other naturally fermented foods. In fact Bimuno has the most potent bifidogenic (Bifidobacteria promoting) effect of any available prebiotic.
Ingestion of Lactobacillus rhamnosus (a strain of PRObiotic) has been demonstrated to modulate information processing strongly linked to anxiety and depression and to improve the neuro-endocrine stress response in lab animals – in plain English, this probiotic turned anxious, fearful mice into mellow ones. In other words, PREbiotic supplementation with Bimuno REDUCED THEIR ANXIETY LEVELS AND OCD THINKING. Results showed that the supplemented group paid less attention to negative information and more attention to positive information than either a group given another type of prebiotic (fructooligosaccharides, FOS) or a group given a placebo.


Taking a prebiotic supplement may relieve their life-impinging symptoms while also improving their overall physical health – without the adverse effects of pharmaceuticals. The research that led to the development of Bimuno demonstrated only Galacto-oligosaccharides (GOS) to be useful in reducing anxiety levels and OCD thinking in the study’s subjects. The increase of hippocampal BDNF after prebiotic intake is consistent with a probiotic effect, and may have been a direct consequence of elevated gut Bifidobacteria numbers. In order to post comments, please make sure JavaScript and Cookies are enabled, and reload the page. They help with digestion, help with boosting immune system functions and even manufacture certain vitamins. When the bacteria grow rapidly they release toxins and these can actually damage the lining of the colon causing the characteristic C difficile colitis which is also called pseudomembranous colitis.
Its lack of popularity probably has more to do with attitudes around the distastefulness of putting feces from a healthy colon into an unhealthy one because the evidence is rather astounding that it works quickly in over 90% percent of cases to stop diarrhea from C diff infection. If our gut flora has already become seriously out of balance, we can also benefit from taking high quality probiotics as supplements to populate the necessary array of friendly bacteria in our gut microbiomes.
An out of balance (dysbiotic) gut microbiome produces a wide variety of symptoms – including anxiety, depression, and OCD. The people who had taken Bimuno® also had lower levels of cortisol (a stress hormone linked with anxiety and depression) in their morning saliva.
Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity ofBifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study. Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers. PYY) or other mediators, such as the immune system resulting from direct oligosaccharide-gut interactions, cannot be ruled out. The elevation of NMDAR subunits after prebiotics is intuitive given their reduction in the brains of germ-free animals.
I would have no less requirements of proof of scientific results for reportedly natural stuff that I would for other stuff. Furthermore, the strong correlation between Bifidobacteria numbers and cortical NR1 levels presented in this report, further supports a link between the microbiota and central glutamate neurotransmission.
Mechanistic investigations beyond the scope of the present study, are now required to ascertain the systems underlying the observed changes, and will also reveal if vagal nerve modulation is involved. Moreover, behavioural analysis in rats will ascertain if the changes in BDNF after prebiotics impart an anxiolytic action, or that increased NMDAR subunits translate to improved cognitive performance.
Importantly, our study has provided sufficient cause to warrant further exploration into the utility of prebiotics in therapies of neuropsychiatric illness and which, by virtue of their ability to proliferate gut bacteria and stimulate neuroendocrine (and other) responses, may even prove to be more potent than probiotics.



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Comments to “Probiotics c diff quarantine”

  1. Sexpotoloq:
    And beverages - a real game changer for majority of our probiotics.
  2. kursant007:
    CFU's to build up in the digestive system are.
  3. Narin_Yagish:
    Between these two oral Probiotics From keep taking probiotics. Stomach.