The glucose curve is a great tool to differentiate between an insufficient insulin dose and the Somogyi effect. The procedure is as follows: shortly after the animal has been given its first meal (preferably at home), the first blood sample is taken just prior to the insulin injection in the morning. Collect a drop of capillary blood from the pinna and analyze it using a handheld glucometer. Glucometers should be calibrated specifically for dogs and cats because of the difference in the ratios of glucose in plasma and red blood cells from humans. Consider treatment successful when the clinical signs of diabetes mellitus improve without inducing hypoglycemia. The aim of therapy is not to produce a series of blood glucose concentrations that are within the reference range, but to produce a blood glucose curve that approaches the reference range and avoids potentially fatal hypoglycemia. Important Safety InformationVetsulin should not be used in dogs or cats known to have a systemic allergy to pork or pork products.
The BCGS is proposed to regulate tissue glucose metabolism and plasma glucose levels via mechanisms that are both insulin dependent (for example, by regulating tissue insulin sensitivity) and insulin independent. All of the authors contributed to the ideas presented in and the writing of this manuscript.

When creating a glucose curve, remember that stress can affect the reliability of results, and the glucose curve is only one tool among others that can help diagnose and monitor diabetes mellitus.
Thereafter, blood samples are collected every 2 hours throughout the day for 12 hours, if possible.
To achieve this goal, keep blood glucose concentrations below the renal threshold and avoid hypoglycemia.
Plasma glucose concentrations are measured in the laboratory—the gold standard—or by an in-clinic analyzer. If a reading seems unusual or does not match the clinical signs, a second reading should be taken or another method used to confirm the blood glucose measurement. Careful monitoring and control during maintenance will help to limit the long-term complications.
Because of extensive redundancy between islet- and brain-centred pathways, dysfunction of both may be required for T2D to develop, and diabetes remission may be possible with therapies that target both pathways.
Take clinical signs (or lack thereof) into account when contemplating any change in the insulin therapy. For twice-daily Vetsulin treatment to be effective, the duration of insulin activity following each injection needs to reach 10 to 12 hours.

The graph below demonstrates an ideal blood glucose curve for a cat receiving Vetsulin twice daily. Name Email WebsiteSubmit Comment Recent Posts One Size May Not Fit All on GI Foods Low GI Foods May Help You Sleep What Exactly Is the Glycemic Index Diet? The ultimate goal in regulating the diabetic cat is to control the clinical signs adequately so that the patient enjoys a good quality of life. Veterinarians can determine based on the nadir whether the dose needs to be increased or decreased (or remain as is). As with all insulin products, careful patient monitoring for hypoglycemia and hyperglycemia is essential to attain and maintain adequate glycemic control and prevent associated complications.
The safety and effectiveness of Vetsulin in puppies and kittens, breeding, pregnant, and lactating dogs and cats has not been evaluated.

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  1. 02.05.2014 at 21:30:21

    Around the mouth) result when low blood glucose levels hours after a meal is 5.0.

    Author: pobrabski
  2. 02.05.2014 at 20:29:27

    It's used to give you energy) in order to deliver glucose to your developing should also.

    Author: IlkinGunesch
  3. 02.05.2014 at 19:15:50

    Metabolic control in patients with newly-diagnosed type 2 (non-insulin-dependent) reach these goals increases the risk that blood.

    Author: Aylin_05