Diabetes affects the vascular system leading to poor blood circulation, reducing oxygen and nutrients to the feet.
Consult a doctor immediately if you experience any of these symptoms, nothing is too insignificant when it comes to dealing with a diabetic foot. When you seek medical help, your doctor will ask you about the different symptoms you experience, and your medical history. Our doctor regularly conducts free public educational forums about diabetic management and steps to prevent amputation at his clinic.
Being among the few vascular and endovascular trained surgeons in Singapore, our doctor can provide comprehensive services from diagnosis to treatment.
Science, Technology and Medicine open access publisher.Publish, read and share novel research. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria.
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. You may have heard people say they have “a touch of diabetes” or that their “sugar is a little high.” These words suggest that diabetes is not a serious disease.
People with diabetes need to make healthy food choices, stay at a healthy weight, move more every day, and take their medicine even when they feel good. Talk to your health care team about how to manage your A1C, Blood pressure, and Cholesterol. The A1C is a blood test that measures average blood sugar level over the past three months. When the body does not produce enough insulin or when cells do not respond to the insulin produced, the person has high blood sugar or diabetes mellitus.
Venous diseases causes nerve damage, numbness, and an inability to feel heat or cold leading toward the development of neuropathy, and other complication.
If you have persistent pain and redness or swelling of the feet and leg ulcers, this could be an indication of an infection or poor blood circulation as a result of arterial diseases.
After a physical exam, your primary care provider may refer you to a podiatrist, or a foot specialist. Our doctor is one of the few doctors in Singapore who is able to do stenting for your foot to treat diabetic foot.
IntroductionDiabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects of insulin action, insulin secretion or both [1]. This is a problem because you need insulin to take the sugar (glucose) from the foods you eat and turn it into energy for your body.


This can help lower your chances of having a heart attack, stroke, or other diabetes problems. Having diabetes changes your physical ability to fight infections and people with diabetes often have to deal with many side effects.
A person with diabetes must carefully inspect feet every day and maintain their primary doctor for routine foot checkups. If you have pain in the legs reaching your buttocks when you walk, and it subsides when you sit, this is a clue to poor circulation. To receive proper diagnosis you may undergo the following: An x-ray revealing bone structure, and detecting any sign of bone infection. It is extremely urgent you complete the entire prescription in order to effect complete healing.
Our clinic always adopts the latest minimally invasive technology to reduce the recovery of our patients. Diabetes has taken place as one of the most important diseases worldwide, reaching epidemic proportions. But even if it goes away, these women and their children have a greater chance of getting diabetes later in life. Poor fitting shoes are a leading cause to minor foot problems that can develop into a serious condition. Any break in the skin, or extreme dry skin needs attention to prevent gangrene from occurring.
A CT scan, also a type of an x-ray that is computerized, having the ability to evaluate types of infections, hidden pus or abscess.
You may be referred to a wound care center specializing in diabetic infections to the feet; determining a treatment plan. Global estimates predict that the proportion of adult population with diabetes will increase 69% for the year 2030 [2].Hyperglycemia in the course of diabetes usually leads to the development of microvascular complications, and diabetic patients are more prone to accelerated atherosclerotic macrovascular disease. If you are experiencing red spots, corns, calluses, and bunions it is vital to attain a better fitting shoe. MRI scan uses magnetic waves to take pictures inside your body also to detect pus and infections.
Being a part of one of the largest multi-disciplinary private health care in Singapore, we have quick access to many doctors from other specialisations to give treatments should your diabetes develop other complications. These complications account for premature mortality and most of the social and economical burden in the long term of diabetes [3].
Sometimes the infections are so severe that they can go into the bones and develop deformities. There are times when the numbness is so severe that the diabetic cannot determine if there are any minor sores, cuts, or scrapes on the bottom of the foot; leading to infections and gangrene.


If you see any red streaking next to cuts, wounds, or redness surrounding the wound this may mean that an infection is spreading. Having the ability to provide a comprehensive service, our doctor will be able to prescribe a customised treatment for you that is best suited for your body and preferences. Increasing evidence suggests that oxidative stress plays a role in the pathogenesis of diabetes mellitus and its complications [4]. Hyperglycemia increases oxidative stress, which contributes to the impairment of the main processes that fail during diabetes, insulin action and insulin secretion. Smoking cigarettes contribute to narrowing blood vessels such as atherosclerosis, which increase complications to the feet. If you notice numbness slowly developing, and lasting longer than a few minutes, this may be nerve damage. In addition, antioxidant mechanisms are diminished in diabetic patients, which may further augment oxidative stress [5, 6]. Constant itching on the bottom of feet may be a sign of fungus this has to be treated, or it can set into a deep infection. As diabetes affects many bodily functions, a consultation may take place with a vascular surgeon together with an orthopedic surgeon.
Oxidative stress At the beginning of life, the organisms obtained their energy (ATP) by anoxygenic photosinthesis, for which oxygen was toxic. Most of the metabolic pathways were developed during this anaerobic stage of life, in which oxygen came later. Cyanobacteria started producing oxygen from photosynthesis, which raised the atmospheric oxygen, and favored those organisms which have evolved into eukaryotic cells with mitochondria, able to use oxygen for a more efficient energy production [9].Whenever a cell’s internal environment is perturbed by infections, disease, toxins or nutritional imbalance, mitochondria diverts electron flow away from itself, forming reactive oxygen species (ROS) and reactive nitrogen species (RNS), thus lowering oxygen consumption. This “oxidative shielding” acts as a defense mechanism for either decreasing cellular uptake of toxic pathogens or chemicals from the environment, or to kill the cell by apoptosis and thus avoid the spreading to neighboring cells [9]. The term “oxidative stress” has been used to define a state in which ROS and RNS reach excessive levels, either by excess production or insufficient removal. Being highly reactive molecules, the pathological consequence of ROS and RNS excess is damage to proteins, lipids and DNA [10]. Consistent with the primary role of ROS and RNS formation, this oxidative stress damage may lead to physiological dysfunction, cell death, pathologies such as diabetes and cancer, and aging of the organism [11].



Continuous blood glucose monitor devices
Recognising signs of hypoglycemia guideline


Comments

  1. 31.01.2016 at 23:44:43


    Comment about my experience as a type test blood sugar.

    Author: BAKILI_QAQAS_KAYIFDA
  2. 31.01.2016 at 10:18:31


    LCHF diet could have caused.

    Author: Sevgi_Qelbli
  3. 31.01.2016 at 15:33:39


    Used to maintain blood glucose control during.

    Author: Kitten
  4. 31.01.2016 at 15:22:52


    Cases may be more challenging commonly used as food due to the destruction of insulin-producing beta cells. Have.

    Author: Nihad123
  5. 31.01.2016 at 18:58:39


    Hypoglycemic symptoms including anxiety, sweating during or after exercise.

    Author: IlkinGunesch