Grand mal seizures or tonic-clonic seizures, according to MayoClinic website, is characterized by a sudden loss of consciousness and followed by severe involuntary muscle contractions.
Grand Mal Seizures occur due to a generalized, abnormal electrical activity, and unregulated impulses throughout the whole brain. Hypoglycemia is the condition wherein there is a sudden drop in the blood glucose levels, which can be caused by several factors, such as too high insulin dose, fasting, and many more.
During hypoglycemia, sudden drop of blood glucose levels can have bad effects to the brain.
Tonic clonic seizures are usually associated with epilepsy, however, there are instances that people who are not epileptic can experience from a single attack of  generalized seizures during their lifetime.

As blood glucose levels rapidly drop, brain cells and different organs in the body are deprived with ATP, the energy source of all cellular functions in the body.
For people who are suffering from frequent seizures, daily doses of anti-seizure medications may be prescribed to help in controlling severity and the occurrence of seizures. During hypoglycemia, the brain’s supply of glucose is decreased, which can cause dizziness, fatigue, sudden weakness, headaches, shorter attention span, confusion, changes in the mental function, and worst, it can cause seizures and coma. Generalized convulsive seizures may be life-threatening when it occurs in certain situations, since it can cause sudden loss of consciousness. Brain is one of the first organs that can be affected with low levels of glucose, since the brain has only a limited glucose reserve.

However, most people suffering from it can feel an aura that they can recognize for an impending seizure attack. Diabetics who are taking daily insulin shots or other diabetic medications should be cautious, since they are at higher risk for grand mal seizures.

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