This issue of endothelial cell health and function is as important to athletes as it is to the general public.
When the 1998 Nobel Prize in Medicine was awarded to 3 American research for their discovery on how the endothelium converts the semi-essential amino acid L-arginine into nitric oxide – as a signaling molecule, there was an explosion of research in this area.
That missing ingredient was and is the fact that every time your blood pulses across the endothelium it creates a sheering force that stimulates the endothelium to release a puff of nitric oxide into the blood stream. As the image shows below, your endothelium loses its ability to properly product nitric oxide as you age. In your 20’s your arteries are generally healthy and clear of obvious disease, though research shows the disease and aging process has already begun.
In your 30’s and 40’s, accumulation of fatty deposits called plaque typically begins to accelerate in men, women are generally protected in their major arteries until after menopause though disease may begin in smaller vessels. In your 50’s, the assault on your endothelium continues while the vessel wall becomes stiffer and more fibrous.
In your 60’s and beyond, the aging process contributes to the attack on the lining of the arteries. However, resent research in human study groups are showing that when properly nourished the endothelium can produce higher levels of nitric oxide.
Learning how to properly nourish your endothelium with the ingredients it needs to optimize its ability to create nitric oxide can have a true health benefit. Winner of Chicago Reader magazine’s “Best Personal Trainer” award, Best Of Chicago 2014 edition. Available for personal training in the Chicago neighborhoods of Andersonville, Bucktown, and Lakeshore East. Sign up free below to receive my weekly health and fitness articles, tips, offers & discounts.
In 2013, over 382 million people around the world had diabetes, and 90% of them had type 2 diabetes. Further reading: You can also read my previous article about 6 reasons you are tired all the time, in which health issues are one of them. Further reading: find here more health warnings your eyes may be sending and how to protect your eyes. Further reading: Read my article about the top 15 causes of headaches and how to get rid of them naturally. Further reading: read my precious articles about top signs that you have candida infection and what to do about it, and how to treat vaginal yeast infection naturally. If you are experiencing some of these symptoms, see your doctor so you can have a blood test and establish if you are indeed suffering from type 2 diabetes. Remember that type 2 diabetes is, to some degree, a preventable disease, and that the complications can be avoided with the right approach to life and health. Being overweight – People with belly fat (visceral obesity) are especially at risk (find how to lose stubborn belly fat for good without counting calories in my ultimate e-book guide Blast Your Belly Fat). Eating an unhealthy diet rich in red meat, unhealthy fats, sugars and processed food – One can of sugary soda a day increases your risk of diabetes by 22% (read my article about what happens to your body when you drink soda).
Generally speaking, you will do a lot if you try to eat healthy, exercise moderately, keep your stress levels under control and avoid bad habits. REALLY good list of symptoms that is all compiled in one place…even ones I had, but was never associated with the developing problem by doctors. This website is designed for educational and informational purposes only, and the content herein should not be mistaken for professional health advice.
Mince pies, pudding and brandy butter, chocolates, - Christmas truly is the season of sugar. Without insulin to mop it up, sugar is left in the bloodstream, which can have seriousA  effects all over the body, sometimes even if diabetes is being controlled by medication. It may cause dementia The sugar slump associated with sweet food and drinks can cause headaches, says Dr Andy Dowson, director of headache services at King's College London.'Migraines tend to be triggered by changes, such as a change in sleep patterns or what you're eating.
Heartbreaking pictures guaranteed to move EVERY pet o How To Get The Best Night's Sleep - Grazia This website uses cookies to improve user experience. Running on empty is an all-too familiar ailment for most modern working women - with getting those advised 7-9 hours shut eye made all the harder by our hectic schedules and inability to switch off. But getting enough kip to leave us bright eyed, and to stop us hitting that snooze button non-stop, could be as easy as a change in routine or diet. We spoke to sleep expert Chireal Shallow of the Henry Potter Advisory Committee to get her advise on why we're losing sleep, and how to can make sure we get the rest we need every night. Obviously there's living under a flight path, noisy neighbours and trying to sleep through sirens, but did you know that where you live dictates how much sleep you get? Lack of routine can have some pretty uncomfortable effects, including that weird falling sensation that wakes you up. Beauty gurus like Liz Earle swear by a little mindfulness to have a good night's sleep.
Waking up with light will help kick-start your body clock, so consider investing in a sunrise lamp if you're someone who finds it hard to lift their head off the pillow and switch on that light.
Diabetes can cause many damaging effects such as diabetes foot swelling, bone infections, nerve damage, blocked blood vessels, blisters, calluses, and collapsed joints.
Diabetes Mellitus is a chronic disease in which your body does not make enough insulin or it is not able to use the insulin it has correctly. Without the help of Insulin to get the sugar into the body cells, the blood sugar builds up causing high blood sugar. Your blood is too thick to reach all the small delicate areas of your body so some body parts start to suffer from not getting enough nutrients. Eating right: pay attention to the carbohydrates you are eating to get them in the right amounts for just what your body needs and not a lot of extra. Exercise: activity helps your body use the insulin better and helps you burn off extra sugar in your blood faster because you need that energy for exercise. The University of Kansas Medical CenterThe University of Kansas prohibits discrimination on the basis of race, color, ethnicity, religion, sex, national origin, age, ancestry, disability, status as a veteran, sexual orientation, marital status, parental status, gender identity, gender expression, and genetic information in the university's programs and activities.
HOW DO YOU KNOW WHAT LDL YOU HAVE?  Certain clinical factors predict the presence of small dense LDL. To determine LDL particle size, ask your doctor for a VAP (Vertical Auto Profile) test, which separates lipoprotein particles using a high speed centrifuge.
If you don’t have insurance and can pay for just one test, get your fasting blood sugar checked. Why just focus on surogate markers, which in their own right are quite imperfect at predicting much of anything? Thanks for a good article but I do believe bill above has a very important point in that risk factors are not the disease. He did say that the arteries could create collateral arteries and she might be completely fine in not having any procedure done. I was a little confused about potatoes, are they okay or is cooking them a certain way (boiled instead of baked?) a healthier way to cook them? People with diet-related heart disease can eat potatoes (not restaurant French fries prepared in unstable vegetable fat that contains excess omega 6). Excess refined carbohydrates and excess vegetable fats (containing excess omega 6 linoleic acid) are the twin culprits in plaquing up our bodies. Research suggests that coronary heart disease (CHD) begins with damage to the lining and inner layers of the coronary (heart) arteries. If the plaque ruptures, blood cell fragments called platelets (PLATE-lets) stick to the site of the injury.
In addition to the factors above, low estrogen levels before or after menopause may play a role in causing coronary microvascular disease (MVD). Kenneth Cooper started the “Aerobic Revolution” and designed some of the standards for measuring athletic performance. This means that has you increase your heart rate through activity you increase the ability of the endothelium to release nitric oxide into the bloodstream.
High blood glucose levels, LDL cholesterol, nicotine, and high blood pressure all cause damage to your endothelium.

Cholesterol, tobacco smoke, high blood pressure and high blood sugar all cause persistent injury to the inner lining of the artery. High blood pressure creates damage apart from plaque build-up that makes arteries less elastic or compliant, increasing the workload on the heart. Left unchecked, plaques can rupture or erode, leading to blood clots that can cause heart attacks and strokes. High levels of nitric oxide can initiate reparative mechanisms that can heal damage done to the endothelium. Coupled with a proper exercise program and you can really make significant improvements in human and athletic performance.
Give your body the fiber it needs and let the sugar from the fruit absorb at the rate it was meant to. Frequent urination (polyuria): If you notice that you have to urinate more often, and you wake up during the night (sometimes several times) to empty your bladder, this could be a warning sign. Increased hunger (polyphagia): Due to extreme highs and lows in blood sugar levels, the body develops a sudden urge to eat.
Dry mouth: You experience a lack of moisture in the mouth, which can be both unpleasant and dangerous. Unexplained weight loss or weight gain: As insulin can’t get glucose into the cells, the body reacts as if it would be starving and starts using proteins from the muscles. Fatigue: Excessive tiredness can develop when body constantly compensates for the lack of glucose in the cells. Headaches – A headache can develop due to elevated blood sugar levels and is considered an early sign of hyperglycemia (high blood glucose). Infections, cuts and bruises that do not heal: This classic sign of diabetes is a consequence of blood vessel damage. Yeast infections: Since bacteria and fungi thrive in a sugary environment, infections can become more common.
Skin changes: Velvety dark skin, known as achantosis nigricans, can appear on the neck, groin and armpit.
Sexual dysfunction: Diabetes also damages blood vessels and nerves in the sex organs, which can lead to different sexual problems. As we get older, the risk of diabetes increases, so it’s even more important to promote a healthy lifestyle and stay active. If you have a medical problem you should seek advice from a doctor and other health care professional. The average British adult will consume the equivalent of 32 teaspoons of the stuff on Christmas Day alone, according to the British Heart Foundation.UK guidelines recommend that we should have no more than 50g - or around ten teaspoons - of sugar a day.
Some scientists are claiming that, calorific content aside, a sugary diet is harmful because it alters crucial processes and hormone levels in the body. In a 2007 French study, rats allowed to choose between sugar and cocaine overwhelmingly chose sugar. People with diabetes are 48a€‰per cent more likely to have a heart attack and 65a€‰per cent more likely to have heart failure, according to the NHS's National Diabetes Audit.
Sometimes setting a bedtime and sticking to it is all you need to do to get a great night's kip.
A study by Appalachian State University in the US found that adults who did a workout early in the day slept longer and deeper than those who did the same exercise later on. As well as tidying out that floordrobe pile making a mess of your room (the stuff on nightmares), investing in some new pillows and soothing beauty buys likes a bedtime candle or pillow spary will help you make your bedroom feel cosy and inviting. The glucose (sugar) in the blood is transformed into the fuel that the body’s cells can use by insulin.
Bone infection is cause by all the other symptoms and can be very serious, or even life threatening.
Common body parts affected are the eyes, kidneys, tips of fingers and toes, stomach and heart.
The good news is, with a little hard work and careful attention your diabetes can be managed well.  So that it does not have to interfere with your ability to have a great, fun, and fulfilling life!
About 50 percent of all people who die suddenly from heart disease have low or normal cholesterol. Lipoprotein(a) has been called the “heart attack cholesterol.” Lipoprotein(a) is a sticky protein that attaches to LDL and accumulates rapidly at the site of arterial lesions or ruptured plaque.
HDL is made in the liver and acts as a cholesterol mop, scavenging loose cholesterol and transporting it back to the liver for recycling. A lot of people with elevated LDL do not develop coronary artery disease, while individuals with low or modest levels often develop serious disease.  This can be explained by the LDL particle number and size.
Under an electron microscope, some LDL particles appear large and fluffy; others small and dense. It’s becoming consensus medical opinion that only oxidized LDL can enter the macrophages in the lining of the arteries and contribute to plaque buildup. The VAP test measures the basic information provided by a routine cholesterol test, but also identifies lipoprotein subclasses, LDL and HDL. I was actually in the process of producing something very similar to this as a quick reference for my clients; you have saved me some work here! Coronary artery plaque is the disease and to date the very best way to access this killer is to measure calcified plaque in the arteries using a CAC scan. As an example, eating eggs and bacon for breakfast will boost HDL and reduce triglycerides; eating box cereal with skim milk will promote triglycerides and reduce HDL. I know it’s not ideal (she has a pacemaker and hypertension) but I asked him about it as an option because of the risks of having balloon surgery. The next big step will be with grains & carbs which I know will be more difficult for her, she has cut back some already, so there is hope. People who are sensitive to carbs or are pre-diabetic or diabetic may need to avoid potatoes and stick with salad vegetables – eating potatoes only occasionally.
Hardened plaque narrows the coronary arteries and reduces the flow of oxygen-rich blood to the heart.
If a clot becomes large enough, it can mostly or completely block a coronary artery and cause a heart attack. Improve heart strength and function coupled with improved aerobic capacity and blood flow could account for most of the gains in athletic performance. This increases vasodilation for improved blood flow and improves the body’s ability to delivery oxygen.
This damage results in inflammation leading to the start of plaque formations that can increase over time. This brings more surface volume back into play leading to more and more healthy endothelial cells for improved nitric oxide production. Also, consuming protein, healthy fats, fiber, or some combination of all of those along WITH the whole fruit will greatly reduce the impact on your blood sugar levels. Production of insulin – a pancreatic hormone that usually deals with balancing blood sugar levels – is either reduced or the cells don’t respond to it properly. As you lose more fluids, the body will try to replenish them, hence the constant need to drink. Dry mouth can become a breeding ground for bacteria and cause different oral and dental problems. Rapid, unexplained weight loss (10 to 20 pounds over a couple of months) is not healthy and requires further investigation. Excessive amounts of sugar harm the veins and arteries, so they become less able to transport blood to where it is needed to repair and heal the damage.
The most frequent ones are yeast infections, such as candida, especially vaginal candida infections in women. You can also observe other unusual skin changes and itchiness, especially around the vaginal or groin area. But surveys suggest the average British adult goes over this by two teaspoons - much of this coming from sugars added to our food by manufacturers.

So can we safely indulge our sweet tooth over the Christmas period?Dr Mark Vanderpump, an endocrinologist at the Royal Free Hampstead NHS Trust in London, says that while most healthy people can get away with the odd sugar binge, there is 'quite a large population in this country who are on the borderline of diabetes, and if they put enough pressure on the system, it may just tip them over the edge'.
This was even true among rats already given so much cocaine they were showing signs of addiction. Scientists found that sugar blocks the action of orexins, a type of brain cell responsible for feelings of wakefulness (orexins are also involved in telling the body to burn calories). That's because the condition causes abnormal cholesterol levels, and changes in the cells lining the blood vessels which lead to them narrowing or stiffening, says Dr David Price, a consultant in endocrinology and diabetes at Morriston Hospital in Swansea.
If you don't sit by a window at work then try your best to get out and about on your lunch break. To attain the optimum temparture during colder months have a blanket at hand and socks if you feel the cold.
Nerve damage occurs when the excessively high glucose levels for extended periods of time damage the nerves, especially the nerves of the lower extremities.
If left untreated, high blood sugars over time can cause diabetes complications, such as problems with eyes, kidneys, nerves, and the heart.
If monitored early enough, elevated CRP can be an early warning of a heart attack several years in advance. Elevated homocysteine is a result of B-vitamin deficiencies, particularly folic acid, B-6 and B-12.
Triglycerides are blood fats made in the liver from excess energy – especially carbohydrates. The big, fluffy particles are benign, while the small dense particles are strongly associated with increased risk of heart disease.
At the same time, however, people need to be prepared for the statin sales pitch they will likely get at their doctor’s office. There’s plenty of evidence that high carbohydrate diets are associated with elevated blood sugar, high insulin, elevated triglycerides and depressed HDL.
In 21 Days to a Healthy Heart, the case study Maria reversed type II diabetes using an Atkins-style diet (confirmed by the Mayo Clinic). Because they are a relatively fast release of sugar in the gut (high glycemic), it makes sense to combine them with a source of natural fat. Improved oxygenation helps you work at a higher aerobic capacity with less lactic acid accumulation. This cumulative damage lessens the ability of the endothelium to produce proper levels of nitric oxide. For women, in which the disease tends to develop 10 to 15 years later than for men, the accumulation of plaque begins to accelerate. As diabetes is a serious condition that can cause dangerous complications – including cardiovascular and neurological damage – it is important to detect it as soon as possible.
If sugar levels are not brought down, the nerve damage can become permanent and presents a serious complication of diabetes. The entire content of this website is copyrighted and should not be copied without permission.
Dr Aseem Malhotra, a London cardiologist and member of the Academy of Medical Royal Colleges obesity group, believes sugar should be regulated like alcohol because it shares four key characteristics. The researchers think this might explain the sleepiness we often experience after aA  big, carbohydrate-heavy meal, since carbohydrates break down into sugar very quickly in the body. Although the majority of sufferers are overweight, it's possible to develop fatty liver disease even with a normal BMI, if your diet is poor.Left untreated, it works in exactly the same way as liver disease caused by alcohol. Also, bear in mind that a mattress reaches it's shelf-life after about nine-10 years - investing in a new one could be a fast track to sleepytime. When glucose levels are high the body suffers damage such as kidney damage, heart damage, nerve damage, and blindness.
When these nerves are damaged it is called peripheral neuropathy and can be characterized by pain and or numbness in the feet. A discussion about LDL subclasses and LDL subclass testing follows in the summary of this article. Elevated homocysteine is associated with increased risk of heart attack, stroke, and all cause mortality.
While the Lp(a) level is largely genetically determined, it can be influenced by nutritional factors, such as high blood sugar and trans fatty acid consumption. As an example, if TG = 80 and HDL = 80, your ratio is 1:1 representing low risk of heart disease. Frying them in lard or using sour cream and butter on baked potatoes slows the sugar-release and adds nutrition.
In fact, a single serving of fruit juice contains the same amount of sugar as three and a half donuts and about 150 calories.
With the right diet, exercise regimen and, if necessary, medications, diabetes can be kept under control, and the person can continue to live a fulfilling life. This numbness can be a contributing factor to wounds and sores on the feet as the decreased sensation causes the diabetic to not be able to sense damage to the foot.
Because Total Cholesterol (TC) and LDL cholesterol are not the most reliable predictors of heart disease, they are not posted in the following chart. If your TG = 200 and your HDL = 50, your ratio is 4:1 representing serious risk of heart disease.
The lack of fiber and high concentration of sugar you get from fruit juice causes blood sugar levels to quickly spike. Find out about some of the early warning signs of diabetes, so you can act on it and protect your health. If you have been diagnosed as prediabetic, read my article about the 7 effective steps to prevent diabetes. Sugar also seems to raise cholesterol.'What people don't realise is that you can develop these problems and have a normal body mass index (BMI). It is caused by the pancreas producing small amounts or none of the chemical called insulin. The decreased sensation can also cause the diabetic to not be able to support themselves as they normally would and this can lead to falls and injuries to the feet ankles and knees.
It worked for Maria – it can work for others too who are overweight, pre-diabetic, and clot-prone. However, if sugar levels stay high for a long period of time, this can cause permanent damage and can even lead to eyesight loss. I see it all in the time in my clinic - people aren't overweight and don't have diabetes, yet they've had a heart attack. When the blood vessels of the lower extremities are blocked and circulation decreases it can cause damage at the cellular level as the cells are unable to receive oxygen and nutrients from the blood. This spike then triggers the release of the hormone insulin to help the body bring those levels back down. I think sugar is one of the main culprits.' Sugar is a particular problem for those with diabetes, a condition that now affects around one in 20 British people. All of these symptoms are made worse by the fact that slow healing is also a sign of diabetes and infections are common. Here, the body becomes resistant to insulin or, in the case of type 1 diabetes, it doesn't produce any insulin at all.
Diabetes foot swelling, nerve damage, and other problems can lead to a greatly decreased quality of life, and the key to heading off the worst effects is appropriate glucose control. In addition, when blood sugar levels come back down you experience the inevitable “sugar crash” which can sometimes cause hunger pangs, sluggishness, and irritability.

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  1. 15.12.2013 at 20:33:17

    Blood sugar levels will cause average blood.

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  2. 15.12.2013 at 11:16:34

    That persists even in fasting states is most with simple blood.

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