J ohnny Depp has warned “no one is safe” from cancel culture and the “instant rush to judgment”.

Hollywood has seemingly turned its back on the actor after he lost his libel battle against the publisher of The Sun over an article which branded him a “wife beater” towards Amber Heard.

The American star told reporters cancel culture has now “got out of hand” when he accepted an award at the San Sebastian International Film Festival on Wednesday.

Johnny Depp and Amber Heard at High Court - In pictures 1 /105 Johnny Depp and Amber Heard at High Court - In pictures Johnny Depp arrives at the High Court on the first day .Jeremy Selwyn Amber Heard arrives at the High Court on the first day PA Johnny Depp on the first day of his libel trial against News Group Newspapers (NGN) AFP via Getty Images Amber Heard with her sister Whitney Heard on the first day Johnny Depp's libel case PA Johnny Depp wearing a face covering AFP via Getty Images) Johnny Depp (right) being cross-examined by Sasha Wass QC (left) before the judge, Mr Justice Nicol, at the High Court on 7 July PA Amber Heard waves as she arrives at the High Court on the second day PA Johnny Depp arrives on the second day of the hearing his libel case Reuters AFP via Getty Images PA Getty Images AFP via Getty Images AFP via Getty Images PA Getty Images Johnny Depp (L) arrives on the third day of his libel trial against News Group Newspapers (NGN), at the High Court on 9 July AFP via Getty Images Johnny Depp arrives at the High Court on 9 July Reuters Photo showing Amber Heard injury alleged to have been caused by Johnny Depp An image Heard said was taken after this incident, showing a bruise on her arm. Lines of cocaine on a table that were allegedly taken by actor Johnny Depp PA An image of Johnny Depp apparently passed out on the floor Amber Heard and Bianca Butti leave the Royal Courts of Justice on 9 July Getty Images Amber Heard (R) arrives on the third day of the libel trial by her former husband US actor Johnny Depp against News Group Newspapers (NGN), at the High Court on 9 July AFP via Getty Images Johnny Depp arrives at the High Court on 9 July AP Amber Heard arrives on the third day of the libel trial by her former husband US actor Johnny Depp against News Group Newspapers (NGN), at the High Court on 9 July AFP via Getty Images Johnny Depp photo spilt ice cream photo referred to in court Amber Heard American actor Johnny Depp gestures to the media as he arrives at the High Court on 13 July AP Amber Heard's pet teacup Yorkshire Terriers Pistol and Boo which has been referred to as an exhibit in the hearing of Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton, at the High Court in London PA One of the pictures shown in court Actor Johnny Depp arrives at the High Court on 14 July PA Johnny Depp with injuries allegedly sustained from Amber Heard during an incident in Los Angeles PA Amber Heard being questioned by Sasha Wass QC as she gives evidence at the High Court in London on 20 July Elizabeth Cook/PA Johnny Depp arrives at the High Court on 20 July AP Amber Heard arrives at the High Court on Monday where she is due to give evidence against former husband Johnny Depp on 20 July PA Amber Heard image which has been referred to as an exhibit in the hearing of Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton, at the High Court on 20 July PA Johnny Depp arrives at Royal Courts of Justice on 21 July Getty Images Amber Heard with a bruising on her face, which was referred to as an exhibit in the hearing of Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton, at the High Court in London PA Amber Heard being cross examined by Eleanor Laws QC as she gives evidence at the High Court in London during a hearing in Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton on 21 July PA Amber Heard with a friend, which was referred to as an exhibit in the hearing of Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton PA Amber Heard arrives at the High Court in London for a hearing in Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton on 21 July PA Johnny Depp leaves the High Court in London following a hearing in his libel case against the publishers of The Sun and its executive editor, Dan Wootton PA Video deposition of Amber Heard in US proceedings, which was referred to as an exhibit in the hearing of Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton, at the High Court PA Johnny Depp with a cast on his hand PA Amber Heard leaves the High Court in London following a hearing in Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton PA Amber Heard arrives at the High Court on Wednesday morning for a hearing in Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton on 22 July PA Actress Amber Heard arrives at the High Court on 22 July AP Amber Heard arrives at the High Court on Wednesday morning for a hearing in Johnny Depp's libel case against the publishers of The Sun and its executive editor, Dan Wootton on 22 July Getty Images PA PA PA PA PA PA PA Amber Heard arrives at the High Court on 23 July Reuters Johnny Depp arrives at the High Court on 23 July REUTERS Johnny Depp arrives at the High Court on 23 July PA Amber Heard arrives at the High Court on 23 July AFP via Getty Images Johnny Depp arrives at the High Court on 23 July AFP via Getty Images Johnny Depp arrives at the High Court on 23 July Getty Images Amber Heard with her girlfriend Bianca Butti arrive at the Royal Courts of Justice on 24 July Getty Images Amber Heard arrives at the Royal Courts of Justice on 24 July Getty Images Amber Heard arrives at the Royal Courts of Justice on 24 July Getty Images Getty Images Getty Images REUTERS PA AFP via Getty Images REUTERS Getty Images AFP via Getty Images SplashNews.com PA REUTERS AFP via Getty Images REUTERS SplashNews.com REUTERS

Speaking out, he said: “It’s a very complex situation, this cancel culture, or this instant rush to judgment based on essentially what amounts to polluted air.

“It’s got so far out of hand that I can assure you, no one is safe. Not one of you, so long as someone is willing to say one thing.

“It takes one sentence, then there’s no more ground, the carpet has been pulled.”

He added: “It’s not just me that it’s happened to. It’s happened to a lot of people: women, men, children have suffered from various types of unpleasantries that sadly at a certain point they begin to think it’s normal, that it’s them. It’s not.”

In March, Depp was refused permission to appeal the ruling in the libel battle against the newspaper.

Just days later, the actor told the world Warner Brothers asked him to resign from his role in the Harry Potter spin-off series Fantastic Beasts.

The star, who has a following of 11.1million on social media, shared his resignation letter on Instagram.

Danish actor Mads Mikkelsen replaced Depp in his character of wizard Gellert Grindelwald.

In August, a US judge ruled Depp could proceed with bringing his $50 million defamation lawsuit against Heard.

The Hollywood actor is suing his actress ex-wife over an op-ed she wrote in the Washington Post about domestic abuse.