{
  "Name": "Skull and brain TSPO PET SUV maps and skull masks, native and MNI152 space",
  "BIDSVersion": "1.2.2",
  "DatasetType": "derivative",
  "GeneratedBy": [
    {
      "Name": "Skull masking",
      "Description": "A skull mask was created by applying a heuristic threshold (0.13) to the pseudoCT image to isolate bone values. Gaps between inner and outer skull layers or other thresholding inaccuracies were corrected by manual editing. An affine transformation matrix was calculated to co-register the PET SUV images to the structural T1-weighted image; the TSPO PET SUV image was then masked with the skull mask to produce the estimated skull PET SUV image."
    },
    {
      "Name": "FreeSurfer",
      "Description": "T1-weighted MR images were processed using the FreeSurfer 'recon-all' pipeline; the resulting brain mask was used to subtract brain signal from the estimated skull PET SUV image, reducing brain-signal contamination of the skull PET data.",
      "CodeURL": "https://surfer.nmr.mgh.harvard.edu/",
      "_Citation": "Fischl B. FreeSurfer. Neuroimage 62, 774-781 (2012)."
    },
    {
      "Name": "ANTs",
      "Description": "Each participant's T1-weighted MR image was registered to the MNI152 T1-weighted standard template using Advanced Normalization Tools (ANTs). The resulting transformation matrices and deformation fields were applied to warp the skull masks and skull PET SUV maps into MNI152 space.",
      "CodeURL": "https://github.com/ANTsX/ANTs",
      "_Citation": "Tustison NJ, Cook PA, Holbrook AJ, et al. The ANTsX ecosystem for quantitative biological and medical imaging. Sci Rep 11 (2021). doi:10.1038/s41598-021-87564-6"
    }
  ]
}