Appearance: "The Luck of the Fryrish"
When the Professor's horse loses upon examination of the finish line with an electron microscope, the god Farnsworth decries his loss with "no fair! You changed the outcome by measuring it!" These words almost perfectly describe the Heisenberg Uncertainly Principle, though that idea refers more to an event's course being altered by the presence of a spectator.
So THAT's where Breaking Bad got it....
