In 2010, Murrieta, California, saw its population reach 103,466, reflecting a dense and rapidly expanding community with 3,078.1 inhabitants per square mile. The city's demographic profile was diverse: 69.7% White (55.7% non-Hispanic White), 5.4% African American, 0.7% Native American, 9.2% Asian, 0.4% Pacific Islander, 8.4% from other races, and 6.1% from two or more races. Notably, 25.9% of the population identified as Hispanic or Latino.

Murrieta's 2010 Census data revealed that 99.6% of its population resided in households, with only a small fraction living in noninstitutionalized group quarters or institutional settings. The city had 32,749 households, of which 48.4% included children under 18. Married opposite-sex couples constituted 62.8% of households, while 11.6% were led by single female householders, and 5.0% by single male householders. Additionally, there were 1,626 unmarried opposite-sex partnerships and 192 same-sex married couples or partnerships. About 15.9% of households were individuals, with 6.9% having someone living alone aged 65 or older. The average household size was 3.15, and the average family size was 3.51.

The age distribution in Murrieta was diverse, with 30.4% of the population under 18, 9.6% aged 18 to 24, 27.2% aged 25 to 44, 22.8% aged 45 to 64, and 10.1% aged 65 or older. The median age was 33.4 years. For every 100 females, there were 95.2 males, and for every 100 females aged 18 and over, there were 91.2 males.

Housing in Murrieta included 35,294 units, averaging 1,050 per square mile. Owner-occupied units accounted for 70.6% of the housing, with a homeowner vacancy rate of 3.1%, while rental units made up 29.4%, with a rental vacancy rate of 7.8%. The majority of the population, 71.1%, lived in owner-occupied housing, while 28.5% resided in rental units.

The 2010 Census data underscores Murrieta's growth and demographic diversity, reflecting its evolution into a vibrant, family-friendly community.