CityPopulationRankMurders Per 100,000 ResidentsViolent Crimes Per 100,000 ResidentsProperty Crimes Per 100,000 Residentsotal Crimes Per 100,000 ResidentsChance of Crime
| Brookings | 22,478 | 1 | 0 | 36 | 178 | 214 | 1:467 |
| Brandon | 9,008 | 2 | 0 | 11 | 355 | 366 | 1:273 |
| Hot Springs | 3,694 | 3 | 0 | 162 | 677 | 839 | 1:119 |
| Lead | 3,189 | 4 | 0 | 125 | 1,160 | 1,285 | 1:78 |
| Sturgis | 6,731 | 5 | 0 | 60 | 2,154 | 2,214 | 1:45 |
| Mobridge | 3,593 | 6 | 0 | 167 | 2,059 | 2,226 | 1:45 |
| Aberdeen | 26,593 | 7 | 0 | 259 | 1,907 | 2,166 | 1:46 |
| Tea | 4,021 | 8 | 0 | 199 | 2,239 | 2,438 | 1:41 |
| Canton | 3,224 | 9 | 0 | 341 | 1,830 | 2,171 | 1:46 |
| Vermillion | 10,826 | 10 | 0 | 277 | 2,291 | 2,568 | 1:39 |
| Watertown | 21,902 | 11 | 0 | 283 | 2,388 | 2,671 | 1:37 |
| Madison | 6,723 | 12 | 15 | 75 | 1,368 | 1,443 | 1:69 |
| Box Elder | 7,997 | 13 | 0 | 288 | 2,527 | 2,815 | 1:36 |
| Spearfish | 10,704 | 14 | 0 | 168 | 3,504 | 3,672 | 1:27 |
| Belle Fourche | 5,739 | 15 | 0 | 418 | 2,195 | 2,613 | 1:38 |
| Yankton | 14,728 | 16 | 0 | 286 | 3,076 | 3,362 | 1:30 |
| Mitchell | 15,541 | 17 | 0 | 327 | 2,787 | 3,114 | 1:32 |
| Huron | 12,849 | 18 | 0 | 319 | 3,339 | 3,658 | 1:27 |
| Sioux Falls | 158,354 | 19 | 1 | 398 | 3,184 | 3,582 | 1:28 |
| Pierre | 14,016 | 20 | 7 | 314 | 3,618 | 3,932 | 1:25 |
| Rapid City | 69,979 | 21 | 6 | 608 | 5,081 | 5,689 | 1:18 |
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