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13_gene-disease_ENSP00000245323", "source_label": "ENSP00000245323", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7179", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_TPTE", "source_label": "TPTE", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000283935", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MIR423", "source_label": "MIR423", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54928", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_BPNT2", "source_label": "BPNT2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "150572", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_SMYD1", "source_label": "SMYD1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27130", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_INVS", "source_label": "INVS", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8218", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_CLTCL1", "source_label": "CLTCL1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7050", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TGIF1", "source_label": "TGIF1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55897", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MESP1", "source_label": "MESP1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1119", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_CHKA", "source_label": "CHKA", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7168", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_TPM1", "source_label": "TPM1", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4878", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_NPPA", "source_label": "NPPA", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1827", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_RCAN1", "source_label": "RCAN1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "182", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_JAG1", "source_label": "JAG1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "100033411", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_DUXB", "source_label": "DUXB", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79156", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLEKHF1", "source_label": "PLEKHF1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "745", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_MYRF", "source_label": "MYRF", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80173", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_IFT74", "source_label": "IFT74", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AL136524.1", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_AL136524.1", "source_label": "AL136524.1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1291", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_COL6A1", "source_label": "COL6A1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "158", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ADSL", "source_label": "ADSL", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9496", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_TBX4", "source_label": "TBX4", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5318", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_PKP2", "source_label": "PKP2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7018", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_TF", "source_label": "TF", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91603", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ZNF830", "source_label": "ZNF830", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "60529", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_ALX4", "source_label": "ALX4", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC126323.2", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_AC126323.2", "source_label": "AC126323.2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6657", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_SOX2", "source_label": "SOX2", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000235191", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_NUCB1-AS1", "source_label": "NUCB1-AS1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5922", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_RASA2", "source_label": "RASA2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6948", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_TCN2", "source_label": "TCN2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "137814", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_NKX2-6", "source_label": "NKX2-6", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000284499", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MIR363", "source_label": "MIR363", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1837", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_DTNA", "source_label": "DTNA", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2627", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_GATA6", "source_label": "GATA6", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5069", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PAPPA", "source_label": "PAPPA", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51621", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_KLF13", "source_label": "KLF13", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3383", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_ICAM1", "source_label": "ICAM1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4659", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_PPP1R12A", "source_label": "PPP1R12A", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9241", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_NOG", "source_label": "NOG", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7290", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_HIRA", "source_label": "HIRA", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8531", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_YBX3", "source_label": "YBX3", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000274258", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_MIR6728", "source_label": "MIR6728", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "728194", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_RSPH10B2", "source_label": "RSPH10B2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8820", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_HESX1", "source_label": "HESX1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57538", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_ALPK3", "source_label": "ALPK3", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6473", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_SHOX", "source_label": "SHOX", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "50805", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_IRX4", "source_label": "IRX4", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5611", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_DNAJC3", "source_label": "DNAJC3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23066", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_CAND2", "source_label": "CAND2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64841", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_GNPNAT1", "source_label": "GNPNAT1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55897", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MESP1", "source_label": "MESP1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4144", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MAT2A", "source_label": "MAT2A", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "60312", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_AFAP1", "source_label": "AFAP1", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6529", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_SLC6A1", "source_label": "SLC6A1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000295641", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_ENSP00000295641", "source_label": "ENSP00000295641", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4552", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_MTRR", "source_label": "MTRR", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83852", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_SETDB2", "source_label": "SETDB2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7546", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ZIC2", "source_label": "ZIC2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000284202", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_MIR137", "source_label": "MIR137", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8643", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_PTCH2", "source_label": "PTCH2", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55552", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_ZNF823", "source_label": "ZNF823", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "201176", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ARHGAP27", "source_label": "ARHGAP27", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "643418", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_LIPN", "source_label": "LIPN", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000284346", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_MIR940", "source_label": "MIR940", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81603", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TRIM8", "source_label": "TRIM8", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6588", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_SLN", "source_label": "SLN", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000293780", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_ENSP00000293780", "source_label": "ENSP00000293780", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "93649", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_MYOCD", "source_label": "MYOCD", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55328", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_RNLS", "source_label": "RNLS", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10560", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_SLC19A2", "source_label": "SLC19A2", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "78987", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_CRELD1", "source_label": "CRELD1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4212", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_MEIS2", "source_label": "MEIS2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23125", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_CAMTA2", "source_label": "CAMTA2", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3207", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXA11", "source_label": "HOXA11", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "30008", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_EFEMP2", "source_label": "EFEMP2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "65250", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CPLANE1", "source_label": "CPLANE1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56992", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_KIF15", "source_label": "KIF15", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3623", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_INHA", "source_label": "INHA", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10175", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CNIH1", "source_label": "CNIH1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9411", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_ARHGAP29", "source_label": "ARHGAP29", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4879", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_NPPB", "source_label": "NPPB", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1787", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_TRDMT1", "source_label": "TRDMT1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "85021", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_REPS1", "source_label": "REPS1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51684", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_SUFU", "source_label": "SUFU", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57545", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CC2D2A", "source_label": "CC2D2A", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84107", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_ZIC4", "source_label": "ZIC4", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9411", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_ARHGAP29", "source_label": "ARHGAP29", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80144", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_FRAS1", "source_label": "FRAS1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4552", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MTRR", "source_label": "MTRR", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83852", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_SETDB2", "source_label": "SETDB2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5365", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXNB3", "source_label": "PLXNB3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55997", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_CFC1", "source_label": "CFC1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55654", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TMEM127", "source_label": "TMEM127", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57549", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_IGSF9", "source_label": "IGSF9", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10637", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_LEFTY1", "source_label": "LEFTY1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000265507", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MIR4435-1", "source_label": "MIR4435-1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7317", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_UBA1", "source_label": "UBA1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7441", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_VPREB1", "source_label": "VPREB1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284252", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_KCTD1", "source_label": "KCTD1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8312", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_AXIN1", "source_label": "AXIN1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "389549", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_FEZF1", "source_label": "FEZF1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7809", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_BSND", "source_label": "BSND", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23129", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PLXND1", "source_label": "PLXND1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84162", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_BLTP1", "source_label": "BLTP1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10284", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SAP18", "source_label": "SAP18", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80781", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_COL18A1", "source_label": "COL18A1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2627", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_GATA6", "source_label": "GATA6", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57549", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_IGSF9", "source_label": "IGSF9", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284273", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_PTGR3", "source_label": "PTGR3", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56729", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_RETN", "source_label": "RETN", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29124", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_LGALS13", "source_label": "LGALS13", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000202560", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_MIR539", "source_label": "MIR539", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "122706", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PSMB11", "source_label": "PSMB11", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "90990", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_KIFC2", "source_label": "KIFC2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7169", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_TPM2", "source_label": "TPM2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "286749", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_STON1-GTF2A1L", "source_label": "STON1-GTF2A1L", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64748", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_PLPPR2", "source_label": "PLPPR2", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7299", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_TYR", "source_label": "TYR", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9469", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_CHST3", "source_label": "CHST3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10021", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_HCN4", "source_label": "HCN4", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2702", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_GJA5", "source_label": "GJA5", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4091", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_SMAD6", "source_label": "SMAD6", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57613", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_FAM234B", "source_label": "FAM234B", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8850", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_KAT2B", "source_label": "KAT2B", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64840", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_PORCN", "source_label": "PORCN", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2187", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_FANCB", "source_label": "FANCB", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5435", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_POLR2F", "source_label": "POLR2F", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3912", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_LAMB1", "source_label": "LAMB1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9496", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_TBX4", "source_label": "TBX4", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5308", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PITX2", "source_label": "PITX2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7412", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_VCAM1", "source_label": "VCAM1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4851", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_NOTCH1", "source_label": "NOTCH1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "28513", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_CDH19", "source_label": "CDH19", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "63947", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_DMRTC1", "source_label": "DMRTC1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "93643", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_TJAP1", "source_label": "TJAP1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3239", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_HOXD13", "source_label": "HOXD13", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "635", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_BHMT", "source_label": "BHMT", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "134701", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_RIPPLY2", "source_label": "RIPPLY2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29895", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_MYL11", "source_label": "MYL11", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "875", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_CBS", "source_label": "CBS", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "30813", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_VSX1", "source_label": "VSX1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23384", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_SPECC1L", "source_label": "SPECC1L", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2175", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_FANCA", "source_label": "FANCA", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54954", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_FAM120C", "source_label": "FAM120C", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000237125", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_HAND2-AS1", "source_label": "HAND2-AS1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "150082", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_LCA5L", "source_label": "LCA5L", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "149954", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_BPIFB4", "source_label": "BPIFB4", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56999", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_ADAMTS9", "source_label": "ADAMTS9", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27077", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_B9D1", "source_label": "B9D1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4867", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_NPHP1", "source_label": "NPHP1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000237728", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_CAMTA1-AS2", "source_label": "CAMTA1-AS2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10817", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_FRS3", "source_label": "FRS3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "537", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_ATP6AP1", "source_label": "ATP6AP1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10370", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_CITED2", "source_label": "CITED2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "246329", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_STAC3", "source_label": "STAC3", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1827", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_RCAN1", "source_label": "RCAN1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000283785", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_MIR15A", "source_label": "MIR15A", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "60412", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_EXOC4", "source_label": "EXOC4", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83852", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SETDB2", "source_label": "SETDB2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2702", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_GJA5", "source_label": "GJA5", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91603", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_ZNF830", "source_label": "ZNF830", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10220", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_GDF11", "source_label": "GDF11", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000207649", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_MIR138-2", "source_label": "MIR138-2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4879", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_NPPB", "source_label": "NPPB", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26005", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_C2CD3", "source_label": "C2CD3", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2737", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_GLI3", "source_label": "GLI3", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10686", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_CLDN16", "source_label": "CLDN16", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27148", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_STK36", "source_label": "STK36", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "162966", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_ZNF600", "source_label": "ZNF600", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9241", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_NOG", "source_label": "NOG", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2252", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_FGF7", "source_label": "FGF7", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "535", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_ATP6V0A1", "source_label": "ATP6V0A1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "138009", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_DCAF4L2", "source_label": "DCAF4L2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84662", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_GLIS2", "source_label": "GLIS2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "130367", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_SGPP2", "source_label": "SGPP2", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2316", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_FLNA", "source_label": "FLNA", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5297", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_PI4KA", "source_label": "PI4KA", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "875", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_CBS", "source_label": "CBS", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64220", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_STRA6", "source_label": "STRA6", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5782", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_PTPN12", "source_label": "PTPN12", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8623", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ASMTL", "source_label": "ASMTL", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10513", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_APPBP2", "source_label": "APPBP2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000244578", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_LINC01391", "source_label": "LINC01391", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "257169", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_C9orf43", "source_label": "C9orf43", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22853", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_LMTK2", "source_label": "LMTK2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "174", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_AFP", "source_label": "AFP", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55677", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_IWS1", "source_label": "IWS1", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "138009", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_DCAF4L2", "source_label": "DCAF4L2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29855", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_UBN1", "source_label": "UBN1", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000283634", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_MIR3155B", "source_label": "MIR3155B", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000319279", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ENSP00000319279", "source_label": "ENSP00000319279", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000205611", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_LINC01597", "source_label": "LINC01597", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "344167", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_FOXI3", "source_label": "FOXI3", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "389668", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_XKR9", "source_label": "XKR9", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5727", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PTCH1", "source_label": "PTCH1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "126820", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_DNAI3", "source_label": "DNAI3", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "257169", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_C9orf43", "source_label": "C9orf43", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51686", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_OAZ3", "source_label": "OAZ3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "594857", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_NPS", "source_label": "NPS", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4524", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_MTHFR", "source_label": "MTHFR", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4624", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_MYH6", "source_label": "MYH6", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23556", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_PIGN", "source_label": "PIGN", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6792", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CDKL5", "source_label": "CDKL5", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27161", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_AGO2", "source_label": "AGO2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57165", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_GJC2", "source_label": "GJC2", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000387760", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_ENSP00000387760", "source_label": "ENSP00000387760", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4487", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_MSX1", "source_label": "MSX1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "347853", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_TBX10", "source_label": "TBX10", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3371", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TNC", "source_label": "TNC", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3383", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_ICAM1", "source_label": "ICAM1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000273874", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_MIR6859-2", "source_label": "MIR6859-2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000176236", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_RPP38-DT", "source_label": "RPP38-DT", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "158326", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_FREM1", "source_label": "FREM1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6242", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_RTKN", "source_label": "RTKN", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23480", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_SEC61G", "source_label": "SEC61G", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "347853", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_TBX10", "source_label": "TBX10", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23521", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_RPL13A", "source_label": "RPL13A", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4036", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_LRP2", "source_label": "LRP2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10133", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_OPTN", "source_label": "OPTN", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "635", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_BHMT", "source_label": "BHMT", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "126014", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_OSCAR", "source_label": "OSCAR", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57659", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_ZBTB4", "source_label": "ZBTB4", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4208", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MEF2C", "source_label": "MEF2C", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "126820", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_DNAI3", "source_label": "DNAI3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "120935", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_CCDC38", "source_label": "CCDC38", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "256144", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_OR4C3", "source_label": "OR4C3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC138747.5", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_AC138747.5", "source_label": "AC138747.5", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22881", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_ANKRD6", "source_label": "ANKRD6", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4851", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_NOTCH1", "source_label": "NOTCH1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2737", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_GLI3", "source_label": "GLI3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23219", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_FBXO28", "source_label": "FBXO28", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7484", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_WNT9B", "source_label": "WNT9B", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1024", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CDK8", "source_label": "CDK8", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7551", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_ZNF3", "source_label": "ZNF3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "308", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_ANXA5", "source_label": "ANXA5", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57572", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_DOCK6", "source_label": "DOCK6", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "861", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_RUNX1", "source_label": "RUNX1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "390883", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_OR7G3", "source_label": "OR7G3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7319", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_UBE2A", "source_label": "UBE2A", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "149465", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_CFAP57", "source_label": "CFAP57", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51268", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_PIPOX", "source_label": "PIPOX", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "200894", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ARL13B", "source_label": "ARL13B", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1381", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_CRABP1", "source_label": "CRABP1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7484", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_WNT9B", "source_label": "WNT9B", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6876", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_TAGLN", "source_label": "TAGLN", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "50511", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SYCP3", "source_label": "SYCP3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27130", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_INVS", "source_label": "INVS", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5613", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PRKX", "source_label": "PRKX", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7476", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_WNT7A", "source_label": "WNT7A", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6299", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_SALL1", "source_label": "SALL1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "254956", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_MORN5", "source_label": "MORN5", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "259293", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_TAS2R30", "source_label": "TAS2R30", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "113189", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_CHST14", "source_label": "CHST14", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2317", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_FLNB", "source_label": "FLNB", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26164", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_MTG2", "source_label": "MTG2", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "265", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_AMELX", "source_label": "AMELX", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5228", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PGF", "source_label": "PGF", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7918", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_GPANK1", "source_label": "GPANK1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "196513", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_DCP1B", "source_label": "DCP1B", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000266750", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_MIR4645", "source_label": "MIR4645", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000205861", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PCOTH", "source_label": "PCOTH", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27443", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_CECR2", "source_label": "CECR2", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1804", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_DPP6", "source_label": "DPP6", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "254956", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_MORN5", "source_label": "MORN5", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000205861", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_PCOTH", "source_label": "PCOTH", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29944", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_PNMA3", "source_label": "PNMA3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54903", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_MKS1", "source_label": "MKS1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000208006", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_MIR16-1", "source_label": "MIR16-1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "HSA-MIR-377-3P", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_HSA-MIR-377-3P", "source_label": "HSA-MIR-377-3P", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55658", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_RNF126", "source_label": "RNF126", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "200894", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ARL13B", "source_label": "ARL13B", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9048", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_ARTN", "source_label": "ARTN", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "389549", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_FEZF1", "source_label": "FEZF1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8802", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SUCLG1", "source_label": "SUCLG1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "253650", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_ANKRD18A", "source_label": "ANKRD18A", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23743", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_BHMT2", "source_label": "BHMT2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6657", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_SOX2", "source_label": "SOX2", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25842", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_ASF1A", "source_label": "ASF1A", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1592", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_CYP26A1", "source_label": "CYP26A1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2627", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_GATA6", "source_label": "GATA6", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "150", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_ADRA2A", "source_label": "ADRA2A", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84366", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_PRAC1", "source_label": "PRAC1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6991", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_DYNLT2", "source_label": "DYNLT2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23129", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXND1", "source_label": "PLXND1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9993", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_DGCR2", "source_label": "DGCR2", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79310", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_OR5H2", "source_label": "OR5H2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2737", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_GLI3", "source_label": "GLI3", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4841", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_NONO", "source_label": "NONO", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "132884", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_EVC2", "source_label": "EVC2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3759", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_KCNJ2", "source_label": "KCNJ2", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000226210", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_WASH8P", "source_label": "WASH8P", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4619", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_MYH1", "source_label": "MYH1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "343069", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_HNRNPCL1", "source_label": "HNRNPCL1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80210", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ARMC9", "source_label": "ARMC9", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55351", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_STK32B", "source_label": "STK32B", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "100288687", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_DUX4", "source_label": "DUX4", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "94", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_ACVRL1", "source_label": "ACVRL1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284086", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_NEK8", "source_label": "NEK8", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4838", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_NODAL", "source_label": "NODAL", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9901", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_SRGAP3", "source_label": "SRGAP3", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "728226", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_GGTLC3", "source_label": "GGTLC3", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55784", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_MCTP2", "source_label": "MCTP2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91147", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TMEM67", "source_label": "TMEM67", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3211", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_HOXB1", "source_label": "HOXB1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7942", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_TFEB", "source_label": "TFEB", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56952", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PRTFDC1", "source_label": "PRTFDC1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "740", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MRPL49", "source_label": "MRPL49", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "113457", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_TUBA3D", "source_label": "TUBA3D", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4524", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_MTHFR", "source_label": "MTHFR", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5454", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_POU3F2", "source_label": "POU3F2", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80279", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CDK5RAP3", "source_label": "CDK5RAP3", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2624", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_GATA2", "source_label": "GATA2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "342132", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_ZNF774", "source_label": "ZNF774", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "53820", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_RIPPLY3", "source_label": "RIPPLY3", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "58190", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_CTDSP1", "source_label": "CTDSP1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54039", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_PCBP3", "source_label": "PCBP3", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "219790", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_RTKN2", "source_label": "RTKN2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55165", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CEP55", "source_label": "CEP55", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10370", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CITED2", "source_label": "CITED2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79809", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TTC21B", "source_label": "TTC21B", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4488", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MSX2", "source_label": "MSX2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5352", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_PLOD2", "source_label": "PLOD2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000106133", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_NSUN5P2", "source_label": "NSUN5P2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "342132", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_ZNF774", "source_label": "ZNF774", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3212", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_HOXB2", "source_label": "HOXB2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4026", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_LPP", "source_label": "LPP", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6909", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TBX2", "source_label": "TBX2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "85366", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_MYLK2", "source_label": "MYLK2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC104134.1", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_AC104134.1", "source_label": "AC104134.1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3759", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_KCNJ2", "source_label": "KCNJ2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000232652", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_LINC02829", "source_label": "LINC02829", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "138046", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_RALYL", "source_label": "RALYL", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5077", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_PAX3", "source_label": "PAX3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7026", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_NR2F2", "source_label": "NR2F2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000176840", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_MIR7-3HG", "source_label": "MIR7-3HG", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7403", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_KDM6A", "source_label": "KDM6A", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9421", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_HAND1", "source_label": "HAND1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51314", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_NME8", "source_label": "NME8", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8481", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_OFD1", "source_label": "OFD1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83895", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_KRTAP1-5", "source_label": "KRTAP1-5", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2253", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_FGF8", "source_label": "FGF8", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "128153", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_SPATA17", "source_label": "SPATA17", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "306", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_ANXA3", "source_label": "ANXA3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5277", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_PIGA", "source_label": "PIGA", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000283634", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_MIR3155B", "source_label": "MIR3155B", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000451207", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_ENSP00000451207", "source_label": "ENSP00000451207", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "122183", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_PRR20A", "source_label": "PRR20A", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10451", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_VAV3", "source_label": "VAV3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "256297", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_PTF1A", "source_label": "PTF1A", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81848", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SPRY4", "source_label": "SPRY4", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2350", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_FOLR2", "source_label": "FOLR2", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "255101", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_CFAP65", "source_label": "CFAP65", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25828", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_TXN2", "source_label": "TXN2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26683", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_OR4F3", "source_label": "OR4F3", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1983", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_EIF5", "source_label": "EIF5", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84520", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_GON7", "source_label": "GON7", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "282996", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_RBM20", "source_label": "RBM20", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8777", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_MPDZ", "source_label": "MPDZ", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56992", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_KIF15", "source_label": "KIF15", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4772", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_NFATC1", "source_label": "NFATC1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54806", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_AHI1", "source_label": "AHI1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2352", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_FOLR3", "source_label": "FOLR3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "657", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_BMPR1A", "source_label": "BMPR1A", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57216", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_VANGL2", "source_label": "VANGL2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10570", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_DPYSL4", "source_label": "DPYSL4", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27341", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_RRP7A", "source_label": "RRP7A", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "170692", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ADAMTS18", "source_label": "ADAMTS18", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9496", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_TBX4", "source_label": "TBX4", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AL354863.1", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_AL354863.1", "source_label": "AL354863.1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000258861", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MIR381HG", "source_label": "MIR381HG", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "DGCR9", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_DGCR9", "source_label": "DGCR9", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79575", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_ABHD8", "source_label": "ABHD8", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1836", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_SLC26A2", "source_label": "SLC26A2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "729262", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_NUTM2B", "source_label": "NUTM2B", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6926", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_TBX3", "source_label": "TBX3", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "171024", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_SYNPO2", "source_label": "SYNPO2", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "431707", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_LHX8", "source_label": "LHX8", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8100", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_IFT88", "source_label": "IFT88", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6469", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SHH", "source_label": "SHH", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000259158", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_ADAM20P1", "source_label": "ADAM20P1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4851", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_NOTCH1", "source_label": "NOTCH1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84987", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_COX14", "source_label": "COX14", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4993", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_OR2C1", "source_label": "OR2C1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55061", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_SUSD4", "source_label": "SUSD4", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "390883", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_OR7G3", "source_label": "OR7G3", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9421", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_HAND1", "source_label": "HAND1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6949", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_TCOF1", "source_label": "TCOF1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000276622", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MIR6499", "source_label": "MIR6499", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "129025", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ZNF280A", "source_label": "ZNF280A", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7139", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_TNNT2", "source_label": "TNNT2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1948", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_EFNB2", "source_label": "EFNB2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "431707", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_LHX8", "source_label": "LHX8", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11346", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_SYNPO", "source_label": "SYNPO", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3670", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_ISL1", "source_label": "ISL1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9546", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_APBA3", "source_label": "APBA3", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000225942", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_LINC01875", "source_label": "LINC01875", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6285", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_S100B", "source_label": "S100B", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "140628", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_GATA5", "source_label": "GATA5", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54806", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_AHI1", "source_label": "AHI1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91851", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_CHRDL1", "source_label": "CHRDL1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7137", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_TNNI3", "source_label": "TNNI3", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "113246", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_C12orf57", "source_label": "C12orf57", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23543", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_RBFOX2", "source_label": "RBFOX2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4853", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_NOTCH2", "source_label": "NOTCH2", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "745", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MYRF", "source_label": "MYRF", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23743", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_BHMT2", "source_label": "BHMT2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22930", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_RAB3GAP1", "source_label": "RAB3GAP1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "112858", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_TP53RK", "source_label": "TP53RK", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10611", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_PDLIM5", "source_label": "PDLIM5", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11341", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_SCRG1", "source_label": "SCRG1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11052", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_CPSF6", "source_label": "CPSF6", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "132884", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_EVC2", "source_label": "EVC2", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91120", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_ZNF682", "source_label": "ZNF682", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000249346", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_LINC01016", "source_label": "LINC01016", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1757", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_SARDH", "source_label": "SARDH", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27143", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_PALD1", "source_label": "PALD1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4053", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_LTBP2", "source_label": "LTBP2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "463", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_ZFHX3", "source_label": "ZFHX3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6469", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_SHH", "source_label": "SHH", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4026", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_LPP", "source_label": "LPP", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23493", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_HEY2", "source_label": "HEY2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AL157895.1", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_AL157895.1", "source_label": "AL157895.1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3664", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_IRF6", "source_label": "IRF6", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2646", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_GCKR", "source_label": "GCKR", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64063", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_PRSS22", "source_label": "PRSS22", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "16", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_AARS1", "source_label": "AARS1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2257", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_FGF12", "source_label": "FGF12", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "14", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_AAMP", "source_label": "AAMP", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3915", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_LAMC1", "source_label": "LAMC1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3664", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_IRF6", "source_label": "IRF6", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "138882", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_OR1N2", "source_label": "OR1N2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10112", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_KIF20A", "source_label": "KIF20A", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10447", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_FAM3C", "source_label": "FAM3C", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000188388", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_GOLGA6L3", "source_label": "GOLGA6L3", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83732", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_RIOK1", "source_label": "RIOK1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54828", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_BCAS3", "source_label": "BCAS3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "78987", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_CRELD1", "source_label": "CRELD1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51588", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_PIAS4", "source_label": "PIAS4", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54903", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MKS1", "source_label": "MKS1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11155", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_LDB3", "source_label": "LDB3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2706", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_GJB2", "source_label": "GJB2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "138882", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_OR1N2", "source_label": "OR1N2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4522", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_MTHFD1", "source_label": "MTHFD1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6469", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SHH", "source_label": "SHH", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1638", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_DCT", "source_label": "DCT", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "129025", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_ZNF280A", "source_label": "ZNF280A", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4625", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_MYH7", "source_label": "MYH7", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "389840", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MAP3K15", "source_label": "MAP3K15", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "63895", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_PIEZO2", "source_label": "PIEZO2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64220", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_STRA6", "source_label": "STRA6", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91120", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ZNF682", "source_label": "ZNF682", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "357", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SHROOM2", "source_label": "SHROOM2", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2169", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_FABP2", "source_label": "FABP2", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000215417", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_MIR17HG", "source_label": "MIR17HG", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2147", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_F2", "source_label": "F2", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9775", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_EIF4A3", "source_label": "EIF4A3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3752", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_KCND3", "source_label": "KCND3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000269416", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_LINC01224", "source_label": "LINC01224", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1678", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TIMM8A", "source_label": "TIMM8A", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "731", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_C8A", "source_label": "C8A", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "118", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_ADD1", "source_label": "ADD1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "341640", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_FREM2", "source_label": "FREM2", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8481", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_OFD1", "source_label": "OFD1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23309", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_SIN3B", "source_label": "SIN3B", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9620", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_CELSR1", "source_label": "CELSR1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "223117", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_SEMA3D", "source_label": "SEMA3D", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1399", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_CRKL", "source_label": "CRKL", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "836", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_CASP3", "source_label": "CASP3", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000239314", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_MORC1-AS1", "source_label": "MORC1-AS1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8560", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_DEGS1", "source_label": "DEGS1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000284087", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_MIR6844", "source_label": "MIR6844", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2303", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_FOXC2", "source_label": "FOXC2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4846", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_NOS3", "source_label": "NOS3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4524", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_MTHFR", "source_label": "MTHFR", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9780", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PIEZO1", "source_label": "PIEZO1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "261734", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_NPHP4", "source_label": "NPHP4", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80173", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_IFT74", "source_label": "IFT74", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "617", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_BCS1L", "source_label": "BCS1L", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2346", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_FOLH1", "source_label": "FOLH1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26548", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_ITGB1BP2", "source_label": "ITGB1BP2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "85002", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_FAM86B1", "source_label": "FAM86B1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "138805", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_OR13F1", "source_label": "OR13F1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "442191", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_OR14J1", "source_label": "OR14J1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8701", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_DNAH11", "source_label": "DNAH11", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "202333", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_CMYA5", "source_label": "CMYA5", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64795", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_RMND5A", "source_label": "RMND5A", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6744", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ITPRID2", "source_label": "ITPRID2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57659", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_ZBTB4", "source_label": "ZBTB4", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7545", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_ZIC1", "source_label": "ZIC1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "137814", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_NKX2-6", "source_label": "NKX2-6", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1983", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_EIF5", "source_label": "EIF5", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9496", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_TBX4", "source_label": "TBX4", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4811", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_NID1", "source_label": "NID1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "815", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_CAMK2A", "source_label": "CAMK2A", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "186", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_AGTR2", "source_label": "AGTR2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000258057", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_BCDIN3D-AS1", "source_label": "BCDIN3D-AS1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1832", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_DSP", "source_label": "DSP", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3908", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_LAMA2", "source_label": "LAMA2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81617", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CAB39L", "source_label": "CAB39L", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3235", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD9", "source_label": "HOXD9", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3239", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD13", "source_label": "HOXD13", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284415", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_VSTM1", "source_label": "VSTM1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000258057", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_BCDIN3D-AS1", "source_label": "BCDIN3D-AS1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83716", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_CRISPLD2", "source_label": "CRISPLD2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "727857", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_BHLHA9", "source_label": "BHLHA9", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "441250", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_TYW1B", "source_label": "TYW1B", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55997", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_CFC1", "source_label": "CFC1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "196513", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_DCP1B", "source_label": "DCP1B", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "100033411", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_DUXB", "source_label": "DUXB", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57514", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_ARHGAP31", "source_label": "ARHGAP31", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10715", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_CERS1", "source_label": "CERS1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1947", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_EFNB1", "source_label": "EFNB1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "682", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_BSG", "source_label": "BSG", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "400224", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_PLEKHD1", "source_label": "PLEKHD1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9546", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_APBA3", "source_label": "APBA3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83716", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CRISPLD2", "source_label": "CRISPLD2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5567", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PRKACB", "source_label": "PRKACB", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4838", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_NODAL", "source_label": "NODAL", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64840", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_PORCN", "source_label": "PORCN", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8481", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_OFD1", "source_label": "OFD1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8029", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_CUBN", "source_label": "CUBN", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23556", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_PIGN", "source_label": "PIGN", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2658", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_GDF2", "source_label": "GDF2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4026", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_LPP", "source_label": "LPP", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000238184", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_CD81-AS1", "source_label": "CD81-AS1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9554", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_SEC22B", "source_label": "SEC22B", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000269821", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_KCNQ1OT1", "source_label": "KCNQ1OT1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2294", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_FOXF1", "source_label": "FOXF1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "400746", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_NCMAP", "source_label": "NCMAP", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56975", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_FAM20C", "source_label": "FAM20C", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1297", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_COL9A1", "source_label": "COL9A1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9436", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_NCR2", "source_label": "NCR2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000232225", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_LINC01047", "source_label": "LINC01047", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79709", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_COLGALT1", "source_label": "COLGALT1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9421", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_HAND1", "source_label": "HAND1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11166", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SOX21", "source_label": "SOX21", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "140628", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_GATA5", "source_label": "GATA5", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84942", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_WDR73", "source_label": "WDR73", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7490", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_WT1", "source_label": "WT1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3213", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_HOXB3", "source_label": "HOXB3", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3670", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_ISL1", "source_label": "ISL1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80199", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_FUZ", "source_label": "FUZ", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8038", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ADAM12", "source_label": "ADAM12", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4522", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_MTHFD1", "source_label": "MTHFD1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55997", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_CFC1", "source_label": "CFC1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "100529257", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_SYNJ2BP-COX16", "source_label": "SYNJ2BP-COX16", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2348", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_FOLR1", "source_label": "FOLR1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4659", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_PPP1R12A", "source_label": "PPP1R12A", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2066", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_ERBB4", "source_label": "ERBB4", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5727", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_PTCH1", "source_label": "PTCH1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "126133", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_ALDH16A1", "source_label": "ALDH16A1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54014", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_BRWD1", "source_label": "BRWD1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54810", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_GIPC2", "source_label": "GIPC2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1260", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_CNGA2", "source_label": "CNGA2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10462", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CLEC10A", "source_label": "CLEC10A", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8085", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_KMT2D", "source_label": "KMT2D", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2138", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_EYA1", "source_label": "EYA1", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55997", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_CFC1", "source_label": "CFC1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57545", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CC2D2A", "source_label": "CC2D2A", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4761", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_NEUROD2", "source_label": "NEUROD2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5567", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_PRKACB", "source_label": "PRKACB", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2113", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_ETS1", "source_label": "ETS1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000235191", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_NUCB1-AS1", "source_label": "NUCB1-AS1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10468", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_FST", "source_label": "FST", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54810", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_GIPC2", "source_label": "GIPC2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6006", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_RHCE", "source_label": "RHCE", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4879", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_NPPB", "source_label": "NPPB", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10797", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MTHFD2", "source_label": "MTHFD2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79770", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TXNDC15", "source_label": "TXNDC15", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8036", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SHOC2", "source_label": "SHOC2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "157506", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_RDH10", "source_label": "RDH10", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3108", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_HLA-DMA", "source_label": "HLA-DMA", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6496", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SIX3", "source_label": "SIX3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "153241", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CEP120", "source_label": "CEP120", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "442184", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_OR2B3", "source_label": "OR2B3", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1954", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MEGF8", "source_label": "MEGF8", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55805", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_LRP2BP", "source_label": "LRP2BP", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "421", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ARVCF", "source_label": "ARVCF", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7290", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_HIRA", "source_label": "HIRA", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51621", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_KLF13", "source_label": "KLF13", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64065", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_PERP", "source_label": "PERP", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54361", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_WNT4", "source_label": "WNT4", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23505", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_TMEM131", "source_label": "TMEM131", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81839", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_VANGL1", "source_label": "VANGL1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81553", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_CYRIA", "source_label": "CYRIA", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "924", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CD7", "source_label": "CD7", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84894", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_LINGO1", "source_label": "LINGO1", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "126820", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_DNAI3", "source_label": "DNAI3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27031", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_NPHP3", "source_label": "NPHP3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9546", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_APBA3", "source_label": "APBA3", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7290", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_HIRA", "source_label": "HIRA", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8425", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_LTBP4", "source_label": "LTBP4", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "730291", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_ZNF735", "source_label": "ZNF735", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5154", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_PDGFA", "source_label": "PDGFA", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81553", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CYRIA", "source_label": "CYRIA", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22950", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_SLC4A1AP", "source_label": "SLC4A1AP", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "53407", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_STX18", "source_label": "STX18", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "132884", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_EVC2", "source_label": "EVC2", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4620", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_MYH2", "source_label": "MYH2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "150082", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_LCA5L", "source_label": "LCA5L", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6392", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_SDHD", "source_label": "SDHD", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7043", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_TGFB3", "source_label": "TGFB3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4878", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_NPPA", "source_label": "NPPA", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2322", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_FLT3", "source_label": "FLT3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AL512631.2", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_AL512631.2", "source_label": "AL512631.2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5156", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PDGFRA", "source_label": "PDGFRA", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6573", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SLC19A1", "source_label": "SLC19A1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "182", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_JAG1", "source_label": "JAG1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4286", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_MITF", "source_label": "MITF", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7461", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_CLIP2", "source_label": "CLIP2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55636", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_CHD7", "source_label": "CHD7", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "659", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_BMPR2", "source_label": "BMPR2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1601", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_DAB2", "source_label": "DAB2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "257", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ALX3", "source_label": "ALX3", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81031", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SLC2A10", "source_label": "SLC2A10", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25836", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_NIPBL", "source_label": "NIPBL", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000283634", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_MIR3155B", "source_label": "MIR3155B", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "50945", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_TBX22", "source_label": "TBX22", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "167681", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_PRSS35", "source_label": "PRSS35", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "HSA-MIR-1257", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_HSA-MIR-1257", "source_label": "HSA-MIR-1257", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "346528", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_OR2A1", "source_label": "OR2A1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "60681", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_FKBP10", "source_label": "FKBP10", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1000", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_CDH2", "source_label": "CDH2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2950", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_GSTP1", "source_label": "GSTP1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54954", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_FAM120C", "source_label": "FAM120C", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2121", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_EVC", "source_label": "EVC", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10253", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SPRY2", "source_label": "SPRY2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "50945", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_TBX22", "source_label": "TBX22", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56623", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_INPP5E", "source_label": "INPP5E", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2262", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_GPC5", "source_label": "GPC5", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "653", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_BMP5", "source_label": "BMP5", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2316", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_FLNA", "source_label": "FLNA", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1910", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_EDNRB", "source_label": "EDNRB", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "167681", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_PRSS35", "source_label": "PRSS35", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4094", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_MAF", "source_label": "MAF", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23704", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_KCNE4", "source_label": "KCNE4", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8292", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_COLQ", "source_label": "COLQ", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "65108", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MARCKSL1", "source_label": "MARCKSL1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64840", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_PORCN", "source_label": "PORCN", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2066", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_ERBB4", "source_label": "ERBB4", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2868", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_GRK4", "source_label": "GRK4", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54859", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ELP6", "source_label": "ELP6", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29980", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_DONSON", "source_label": "DONSON", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "729747", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_ZNF878", "source_label": "ZNF878", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2969", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_GTF2I", "source_label": "GTF2I", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6573", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_SLC19A1", "source_label": "SLC19A1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "256380", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_SCML4", "source_label": "SCML4", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6590", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_SLPI", "source_label": "SLPI", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000273874", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MIR6859-2", "source_label": "MIR6859-2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "129025", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_ZNF280A", "source_label": "ZNF280A", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6657", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_SOX2", "source_label": "SOX2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1948", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_EFNB2", "source_label": "EFNB2", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7857", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_SCG2", "source_label": "SCG2", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8241", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_RBM10", "source_label": "RBM10", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4838", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_NODAL", "source_label": "NODAL", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000266589", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_MIR4512", "source_label": "MIR4512", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000189366", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_ALG1L", "source_label": "ALG1L", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54903", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_MKS1", "source_label": "MKS1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23300", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_ATMIN", "source_label": "ATMIN", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "90580", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_TIMM29", "source_label": "TIMM29", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56971", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CEACAM19", "source_label": "CEACAM19", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5268", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SERPINB5", "source_label": "SERPINB5", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80184", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_CEP290", "source_label": "CEP290", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "153", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_ADRB1", "source_label": "ADRB1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "285600", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_KIAA0825", "source_label": "KIAA0825", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "341640", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_FREM2", "source_label": "FREM2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79600", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TCTN1", "source_label": "TCTN1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4208", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_MEF2C", "source_label": "MEF2C", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "70", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_ACTC1", "source_label": "ACTC1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3238", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD12", "source_label": "HOXD12", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5156", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PDGFRA", "source_label": "PDGFRA", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3623", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_INHA", "source_label": "INHA", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "275", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_AMT", "source_label": "AMT", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000255036", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_SUGT1P4-STRA6LP-CCDC180", "source_label": "SUGT1P4-STRA6LP-CCDC180", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4208", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MEF2C", "source_label": "MEF2C", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5606", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_MAP2K3", "source_label": "MAP2K3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2294", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_FOXF1", "source_label": "FOXF1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000266507", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MIR4479", "source_label": "MIR4479", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "253943", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_YTHDF3", "source_label": "YTHDF3", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9786", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_KIAA0586", "source_label": "KIAA0586", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7412", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_VCAM1", "source_label": "VCAM1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2359", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_FPR3", "source_label": "FPR3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4487", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_MSX1", "source_label": "MSX1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2700", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_GJA3", "source_label": "GJA3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29928", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_TIMM22", "source_label": "TIMM22", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "TNKS2-AS1", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_TNKS2-AS1", "source_label": "TNKS2-AS1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27440", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_HDHD5", "source_label": "HDHD5", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1539", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_CYLC2", "source_label": "CYLC2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10715", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_CERS1", "source_label": "CERS1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64795", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_RMND5A", "source_label": "RMND5A", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51311", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_TLR8", "source_label": "TLR8", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7373", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_COL14A1", "source_label": "COL14A1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000235885", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_LINC01828", "source_label": "LINC01828", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000485452", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_ENSP00000485452", "source_label": "ENSP00000485452", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25759", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_SHC2", "source_label": "SHC2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6468", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_FBXW4", "source_label": "FBXW4", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1539", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CYLC2", "source_label": "CYLC2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8857", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_FCGBP", "source_label": "FCGBP", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7267", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_TTC3", "source_label": "TTC3", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26053", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_AUTS2", "source_label": "AUTS2", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23336", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SYNM", "source_label": "SYNM", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56729", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_RETN", "source_label": "RETN", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29124", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_LGALS13", "source_label": "LGALS13", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AL136419.1", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_AL136419.1", "source_label": "AL136419.1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC126468.1", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_AC126468.1", "source_label": "AC126468.1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3199", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXA2", "source_label": "HOXA2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2637", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_GBX2", "source_label": "GBX2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11284", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PNKP", "source_label": "PNKP", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1979", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_EIF4EBP2", "source_label": "EIF4EBP2", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9980", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_DOP1B", "source_label": "DOP1B", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6909", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_TBX2", "source_label": "TBX2", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5068", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_REG3A", "source_label": "REG3A", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4613", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_MYCN", "source_label": "MYCN", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4772", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_NFATC1", "source_label": "NFATC1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000265539", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MIR3164", "source_label": "MIR3164", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23059", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_CLUAP1", "source_label": "CLUAP1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7750", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ZMYM2", "source_label": "ZMYM2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000304169", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_ENSP00000304169", "source_label": "ENSP00000304169", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7026", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_NR2F2", "source_label": "NR2F2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3383", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_ICAM1", "source_label": "ICAM1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64410", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_KLHL25", "source_label": "KLHL25", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "182", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_JAG1", "source_label": "JAG1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51684", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SUFU", "source_label": "SUFU", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "286464", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CFAP47", "source_label": "CFAP47", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64795", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_RMND5A", "source_label": "RMND5A", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6299", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_SALL1", "source_label": "SALL1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55573", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_CDV3", "source_label": "CDV3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9421", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_HAND1", "source_label": "HAND1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51268", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_PIPOX", "source_label": "PIPOX", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27086", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_FOXP1", "source_label": "FOXP1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23389", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_MED13L", "source_label": "MED13L", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84984", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_CEP19", "source_label": "CEP19", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9590", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_AKAP12", "source_label": "AKAP12", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64220", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_STRA6", "source_label": "STRA6", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6604", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_SMARCD3", "source_label": "SMARCD3", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8646", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_CHRD", "source_label": "CHRD", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "FO681492.1", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_FO681492.1", "source_label": "FO681492.1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79867", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TCTN2", "source_label": "TCTN2", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81576", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_YJU2B", "source_label": "YJU2B", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "89910", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_UBE3B", "source_label": "UBE3B", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000202560", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_MIR539", "source_label": "MIR539", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23389", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MED13L", "source_label": "MED13L", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22797", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_TFEC", "source_label": "TFEC", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6470", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_SHMT1", "source_label": "SHMT1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55957", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_LIN37", "source_label": "LIN37", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10826", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_FAXDC2", "source_label": "FAXDC2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9343", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_EFTUD2", "source_label": "EFTUD2", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3670", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_ISL1", "source_label": "ISL1", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1585", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_CYP11B2", "source_label": "CYP11B2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7080", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_NKX2-1", "source_label": "NKX2-1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79848", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CSPP1", "source_label": "CSPP1", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4772", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_NFATC1", "source_label": "NFATC1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51805", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_COQ3", "source_label": "COQ3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3142", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_HLX", "source_label": "HLX", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9915", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ARNT2", "source_label": "ARNT2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4638", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_MYLK", "source_label": "MYLK", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000257495", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_KRT73-AS1", "source_label": "KRT73-AS1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9510", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ADAMTS1", "source_label": "ADAMTS1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "182", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_JAG1", "source_label": "JAG1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54949", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_SDHAF2", "source_label": "SDHAF2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000265841", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_MIR548X", "source_label": "MIR548X", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "253650", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_ANKRD18A", "source_label": "ANKRD18A", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22797", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TFEC", "source_label": "TFEC", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1105", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_CHD1", "source_label": "CHD1", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7026", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_NR2F2", "source_label": "NR2F2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1209", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_CLPTM1", "source_label": "CLPTM1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000265507", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_MIR4435-1", "source_label": "MIR4435-1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4548", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_MTR", "source_label": "MTR", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1719", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_DHFR", "source_label": "DHFR", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23347", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_SMCHD1", "source_label": "SMCHD1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000352561", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_ENSP00000352561", "source_label": "ENSP00000352561", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51520", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_LARS1", "source_label": "LARS1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3228", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXC12", "source_label": "HOXC12", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29958", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_DMGDH", "source_label": "DMGDH", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91057", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_CCDC34", "source_label": "CCDC34", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51324", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_SPG21", "source_label": "SPG21", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "165", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_AEBP1", "source_label": "AEBP1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91147", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TMEM67", "source_label": "TMEM67", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1209", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CLPTM1", "source_label": "CLPTM1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "473", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_RERE", "source_label": "RERE", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6663", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_SOX10", "source_label": "SOX10", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "431705", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_ASTL", "source_label": "ASTL", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC093614.1", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_AC093614.1", "source_label": "AC093614.1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29958", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_DMGDH", "source_label": "DMGDH", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000451411", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_ENSP00000451411", "source_label": "ENSP00000451411", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3182", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_HNRNPAB", "source_label": "HNRNPAB", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23111", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SPART", "source_label": "SPART", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "119016", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_AGAP4", "source_label": "AGAP4", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23765", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_IL17RA", "source_label": "IL17RA", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9657", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_IQCB1", "source_label": "IQCB1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000370256", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_ENSP00000370256", "source_label": "ENSP00000370256", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57619", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SHROOM3", "source_label": "SHROOM3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2784", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_GNB3", "source_label": "GNB3", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25814", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ATXN10", "source_label": "ATXN10", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55636", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_CHD7", "source_label": "CHD7", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2737", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_GLI3", "source_label": "GLI3", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1723", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_DHODH", "source_label": "DHODH", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57619", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_SHROOM3", "source_label": "SHROOM3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9241", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_NOG", "source_label": "NOG", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "388284", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_C16orf86", "source_label": "C16orf86", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79583", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TMEM231", "source_label": "TMEM231", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "182", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_JAG1", "source_label": "JAG1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "261734", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_NPHP4", "source_label": "NPHP4", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1059", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_CENPB", "source_label": "CENPB", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000278851", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MIR6879", "source_label": "MIR6879", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "124923", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_RSKR", "source_label": "RSKR", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "133558", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MROH2B", "source_label": "MROH2B", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "129285", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PPP1R21", "source_label": "PPP1R21", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23207", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_PLEKHM2", "source_label": "PLEKHM2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "285513", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_GPRIN3", "source_label": "GPRIN3", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "348093", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_RBPMS2", "source_label": "RBPMS2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2736", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_GLI2", "source_label": "GLI2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000199990", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_VTRNA1-1", "source_label": "VTRNA1-1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6469", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SHH", "source_label": "SHH", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2294", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_FOXF1", "source_label": "FOXF1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "89796", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_NAV1", "source_label": "NAV1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79693", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_YRDC", "source_label": "YRDC", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "116159", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_CYYR1", "source_label": "CYYR1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6496", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SIX3", "source_label": "SIX3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5055", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SERPINB2", "source_label": "SERPINB2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6470", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SHMT1", "source_label": "SHMT1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4621", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_MYH3", "source_label": "MYH3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "129025", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_ZNF280A", "source_label": "ZNF280A", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5080", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_PAX6", "source_label": "PAX6", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9659", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_PDE4DIP", "source_label": "PDE4DIP", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3268", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_AGFG2", "source_label": "AGFG2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2737", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_GLI3", "source_label": "GLI3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000226864", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_ATE1-AS1", "source_label": "ATE1-AS1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284273", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_PTGR3", "source_label": "PTGR3", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "590", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_BCHE", "source_label": "BCHE", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "933", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CD22", "source_label": "CD22", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5077", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PAX3", "source_label": "PAX3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "28227", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PPP2R3B", "source_label": "PPP2R3B", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "403", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ARL3", "source_label": "ARL3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "648791", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PPP1R3G", "source_label": "PPP1R3G", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23230", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_VPS13A", "source_label": "VPS13A", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "122183", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_PRR20A", "source_label": "PRR20A", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3313", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_HSPA9", "source_label": "HSPA9", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "195827", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_PRXL2C", "source_label": "PRXL2C", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2790", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_GNG10", "source_label": "GNG10", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1000", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_CDH2", "source_label": "CDH2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54987", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_CZIB", "source_label": "CZIB", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "673", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_BRAF", "source_label": "BRAF", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "261734", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_NPHP4", "source_label": "NPHP4", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "65250", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_CPLANE1", "source_label": "CPLANE1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4548", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_MTR", "source_label": "MTR", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4524", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MTHFR", "source_label": "MTHFR", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6909", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_TBX2", "source_label": "TBX2", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5125", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_PCSK5", "source_label": "PCSK5", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23493", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_HEY2", "source_label": "HEY2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000206552", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_KRBOX1-AS1", "source_label": "KRBOX1-AS1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56180", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MOSPD1", "source_label": "MOSPD1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57057", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_TBX20", "source_label": "TBX20", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5228", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PGF", "source_label": "PGF", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4838", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_NODAL", "source_label": "NODAL", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "389840", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MAP3K15", "source_label": "MAP3K15", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "43847", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_KLK14", "source_label": "KLK14", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000229630", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_LINC01264", "source_label": "LINC01264", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54968", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_TMEM70", "source_label": "TMEM70", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2063", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_NR2F6", "source_label": "NR2F6", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "147495", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_APCDD1", "source_label": "APCDD1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1636", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_ACE", "source_label": "ACE", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "113189", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_CHST14", "source_label": "CHST14", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79648", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_MCPH1", "source_label": "MCPH1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23765", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_IL17RA", "source_label": "IL17RA", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81031", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_SLC2A10", "source_label": "SLC2A10", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55746", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_NUP133", "source_label": "NUP133", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83758", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_RBP5", "source_label": "RBP5", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84978", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_FRMD5", "source_label": "FRMD5", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23133", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_PHF8", "source_label": "PHF8", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83700", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_JAM3", "source_label": "JAM3", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "89885", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_FATE1", "source_label": "FATE1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6016", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_RIT1", "source_label": "RIT1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC011379.2", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_AC011379.2", "source_label": "AC011379.2", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "348", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_APOE", "source_label": "APOE", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5293", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_PIK3CD", "source_label": "PIK3CD", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9343", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_EFTUD2", "source_label": "EFTUD2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2318", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_FLNC", "source_label": "FLNC", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4015", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_LOX", "source_label": "LOX", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "293", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SLC25A6", "source_label": "SLC25A6", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10252", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SPRY1", "source_label": "SPRY1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26164", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_MTG2", "source_label": "MTG2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ABL1", "source_label": "ABL1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8470", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_SORBS2", "source_label": "SORBS2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6007", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_RHD", "source_label": "RHD", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56288", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PARD3", "source_label": "PARD3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "BX546450.1", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_BX546450.1", "source_label": "BX546450.1", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4838", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_NODAL", "source_label": "NODAL", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80712", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_ESX1", "source_label": "ESX1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "643418", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_LIPN", "source_label": "LIPN", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84314", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_TMEM107", "source_label": "TMEM107", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10588", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MTHFS", "source_label": "MTHFS", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "137814", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_NKX2-6", "source_label": "NKX2-6", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56180", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MOSPD1", "source_label": "MOSPD1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3845", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_KRAS", "source_label": "KRAS", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6926", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TBX3", "source_label": "TBX3", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "282996", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_RBM20", "source_label": "RBM20", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000225791", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_TRAM2-AS1", "source_label": "TRAM2-AS1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10734", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_STAG3", "source_label": "STAG3", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC126323.2", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_AC126323.2", "source_label": "AC126323.2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9212", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_AURKB", "source_label": "AURKB", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64978", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_MRPL38", "source_label": "MRPL38", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55658", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_RNF126", "source_label": "RNF126", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "78987", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_CRELD1", "source_label": "CRELD1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51318", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_MRPL35", "source_label": "MRPL35", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "129025", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_ZNF280A", "source_label": "ZNF280A", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC093627.27", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_AC093627.27", "source_label": "AC093627.27", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22853", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_LMTK2", "source_label": "LMTK2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64220", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_STRA6", "source_label": "STRA6", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6794", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_STK11", "source_label": "STK11", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84224", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_NBPF3", "source_label": "NBPF3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4149", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_MAX", "source_label": "MAX", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80184", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CEP290", "source_label": "CEP290", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "388591", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_RNF207", "source_label": "RNF207", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27302", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_BMP10", "source_label": "BMP10", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23649", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_POLA2", "source_label": "POLA2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9812", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_DELE1", "source_label": "DELE1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57680", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_CHD8", "source_label": "CHD8", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2731", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_GLDC", "source_label": "GLDC", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "115361", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_GBP4", "source_label": "GBP4", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "256764", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_WDR72", "source_label": "WDR72", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51816", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_ADA2", "source_label": "ADA2", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55295", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_KLHL26", "source_label": "KLHL26", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2296", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_FOXC1", "source_label": "FOXC1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "153572", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_IRX2", "source_label": "IRX2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23654", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXNB2", "source_label": "PLXNB2", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5069", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PAPPA", "source_label": "PAPPA", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3508", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_IGHMBP2", "source_label": "IGHMBP2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9027", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_NAT8", "source_label": "NAT8", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "121275", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_OR10AD1", "source_label": "OR10AD1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6569", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SLC34A1", "source_label": "SLC34A1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "537", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_ATP6AP1", "source_label": "ATP6AP1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000242686", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_PDE6B-AS1", "source_label": "PDE6B-AS1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "123283", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_TARS3", "source_label": "TARS3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4552", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_MTRR", "source_label": "MTRR", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5362", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXNA2", "source_label": "PLXNA2", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8624", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_PSMG1", "source_label": "PSMG1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8820", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_HESX1", "source_label": "HESX1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "158326", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_FREM1", "source_label": "FREM1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3215", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_HOXB5", "source_label": "HOXB5", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000283609", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_MIR4662A", "source_label": "MIR4662A", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55897", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_MESP1", "source_label": "MESP1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2665", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_GDI2", "source_label": "GDI2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_NAT2", "source_label": "NAT2", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7044", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_LEFTY2", "source_label": "LEFTY2", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4036", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_LRP2", "source_label": "LRP2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55521", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_TRIM36", "source_label": "TRIM36", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2294", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_FOXF1", "source_label": "FOXF1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56244", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_BTNL2", "source_label": "BTNL2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10133", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_OPTN", "source_label": "OPTN", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7546", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ZIC2", "source_label": "ZIC2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6899", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_TBX1", "source_label": "TBX1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79025", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_FNDC11", "source_label": "FNDC11", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1543", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_CYP1A1", "source_label": "CYP1A1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000284419", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MIR663A", "source_label": "MIR663A", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "318", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_NUDT2", "source_label": "NUDT2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23710", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_GABARAPL1", "source_label": "GABARAPL1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55124", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PIWIL2", "source_label": "PIWIL2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9569", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_GTF2IRD1", "source_label": "GTF2IRD1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10512", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_SEMA3C", "source_label": "SEMA3C", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "113278", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SLC52A3", "source_label": "SLC52A3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "386746", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_MRGPRG", "source_label": "MRGPRG", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6278", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_S100A7", "source_label": "S100A7", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64782", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_AEN", "source_label": "AEN", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "65084", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_TMEM135", "source_label": "TMEM135", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000202560", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_MIR539", "source_label": "MIR539", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2626", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_GATA4", "source_label": "GATA4", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284273", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_PTGR3", "source_label": "PTGR3", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "151525", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_WDSUB1", "source_label": "WDSUB1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9620", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_CELSR1", "source_label": "CELSR1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5818", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_NECTIN1", "source_label": "NECTIN1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000478319", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_ENSP00000478319", "source_label": "ENSP00000478319", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51012", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_PRELID3B", "source_label": "PRELID3B", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3236", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD10", "source_label": "HOXD10", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64782", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_AEN", "source_label": "AEN", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2712", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_GK2", "source_label": "GK2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2200", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_FBN1", "source_label": "FBN1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51389", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_RWDD1", "source_label": "RWDD1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000204148", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_LINC00474", "source_label": "LINC00474", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "390992", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_HES3", "source_label": "HES3", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55588", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_MED29", "source_label": "MED29", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5818", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_NECTIN1", "source_label": "NECTIN1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83690", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CRISPLD1", "source_label": "CRISPLD1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "745", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_MYRF", "source_label": "MYRF", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "253190", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_SERHL2", "source_label": "SERHL2", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8817", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_FGF18", "source_label": "FGF18", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "60", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ACTB", "source_label": "ACTB", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51389", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_RWDD1", "source_label": "RWDD1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000204148", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_LINC00474", "source_label": "LINC00474", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7353", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_UFD1", "source_label": "UFD1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000106133", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_NSUN5P2", "source_label": "NSUN5P2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91851", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_CHRDL1", "source_label": "CHRDL1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23513", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_SCRIB", "source_label": "SCRIB", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79192", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_IRX1", "source_label": "IRX1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7137", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_TNNI3", "source_label": "TNNI3", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "164714", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_TTLL8", "source_label": "TTLL8", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2175", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_FANCA", "source_label": "FANCA", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "845", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_CASQ2", "source_label": "CASQ2", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "122706", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PSMB11", "source_label": "PSMB11", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC124248.1", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_AC124248.1", "source_label": "AC124248.1", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9787", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_DLGAP5", "source_label": "DLGAP5", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2944", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_GSTM1", "source_label": "GSTM1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6487", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_ST3GAL3", "source_label": "ST3GAL3", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "644890", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_MEIG1", "source_label": "MEIG1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3240", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_HP", "source_label": "HP", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27063", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_ANKRD1", "source_label": "ANKRD1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3360", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_HTR4", "source_label": "HTR4", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "164714", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_TTLL8", "source_label": "TTLL8", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3670", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ISL1", "source_label": "ISL1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84667", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_HES7", "source_label": "HES7", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84455", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_EFCAB7", "source_label": "EFCAB7", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2315", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_MLANA", "source_label": "MLANA", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000281828", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_HERC2P7", "source_label": "HERC2P7", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "140628", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_GATA5", "source_label": "GATA5", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "C20orf197", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_C20orf197", "source_label": "C20orf197", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7021", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_TFAP2B", "source_label": "TFAP2B", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5420", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_PODXL", "source_label": "PODXL", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5307", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_PITX1", "source_label": "PITX1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "283358", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_B4GALNT3", "source_label": "B4GALNT3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "579", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_NKX3-2", "source_label": "NKX3-2", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5686", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_PSMA5", "source_label": "PSMA5", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11278", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_KLF12", "source_label": "KLF12", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "360200", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_TMPRSS9", "source_label": "TMPRSS9", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25759", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_SHC2", "source_label": "SHC2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2697", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_GJA1", "source_label": "GJA1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "330", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_BIRC3", "source_label": "BIRC3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3845", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_KRAS", "source_label": "KRAS", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55636", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CHD7", "source_label": "CHD7", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "92126", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_DSEL", "source_label": "DSEL", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "92104", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_TTC30A", "source_label": "TTC30A", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22981", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_NINL", "source_label": "NINL", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2296", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_FOXC1", "source_label": "FOXC1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5500", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_PPP1CB", "source_label": "PPP1CB", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "284415", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_VSTM1", "source_label": "VSTM1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79192", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_IRX1", "source_label": "IRX1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3110", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_MNX1", "source_label": "MNX1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80067", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_DCAF17", "source_label": "DCAF17", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2627", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_GATA6", "source_label": "GATA6", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8312", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_AXIN1", "source_label": "AXIN1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6658", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_SOX3", "source_label": "SOX3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000179994", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_SPDYE7P", "source_label": "SPDYE7P", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23646", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_PLD3", "source_label": "PLD3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000205611", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_LINC01597", "source_label": "LINC01597", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "250", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_ALPP", "source_label": "ALPP", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000199077", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_MIR129-2", "source_label": "MIR129-2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56181", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_MTFR1L", "source_label": "MTFR1L", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1636", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_ACE", "source_label": "ACE", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC126323.2", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_AC126323.2", "source_label": "AC126323.2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1906", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_EDN1", "source_label": "EDN1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "59", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_ACTA2", "source_label": "ACTA2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10293", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_TRAIP", "source_label": "TRAIP", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7026", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_NR2F2", "source_label": "NR2F2", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23405", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_DICER1", "source_label": "DICER1", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3233", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD4", "source_label": "HOXD4", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56111", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_PCDHGA4", "source_label": "PCDHGA4", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7027", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_TFDP1", "source_label": "TFDP1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "390264", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_OR10G4", "source_label": "OR10G4", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "60529", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_ALX4", "source_label": "ALX4", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5362", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_PLXNA2", "source_label": "PLXNA2", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5308", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_PITX2", "source_label": "PITX2", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "59", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_ACTA2", "source_label": "ACTA2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "90665", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_TBL1Y", "source_label": "TBL1Y", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79813", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_EHMT1", "source_label": "EHMT1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000250490", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_FLJ33360", "source_label": "FLJ33360", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "730291", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ZNF735", "source_label": "ZNF735", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22976", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_PAXIP1", "source_label": "PAXIP1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "137814", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_NKX2-6", "source_label": "NKX2-6", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1826", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_DSCAM", "source_label": "DSCAM", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "114822", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_RHPN1", "source_label": "RHPN1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7389", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_UROD", "source_label": "UROD", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "43", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_ACHE", "source_label": "ACHE", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000233496", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_SYNJ2-IT1", "source_label": "SYNJ2-IT1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11060", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_WWP2", "source_label": "WWP2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57674", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_RNF213", "source_label": "RNF213", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23345", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_SYNE1", "source_label": "SYNE1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2488", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_FSHB", "source_label": "FSHB", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "652", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_BMP4", "source_label": "BMP4", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57822", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_GRHL3", "source_label": "GRHL3", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10715", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_CERS1", "source_label": "CERS1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "959", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CD40LG", "source_label": "CD40LG", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23564", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_DDAH2", "source_label": "DDAH2", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "221391", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_OPN5", "source_label": "OPN5", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "174", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_AFP", "source_label": "AFP", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "120892", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_LRRK2", "source_label": "LRRK2", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4879", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_NPPB", "source_label": "NPPB", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC104123.1", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_AC104123.1", "source_label": "AC104123.1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "127534", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_GJB4", "source_label": "GJB4", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2273", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_FHL1", "source_label": "FHL1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1947", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_EFNB1", "source_label": "EFNB1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1983", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_EIF5", "source_label": "EIF5", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2626", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_GATA4", "source_label": "GATA4", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2696", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_GIPR", "source_label": "GIPR", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6911", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_TBX6", "source_label": "TBX6", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10084", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_PQBP1", "source_label": "PQBP1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23049", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_SMG1", "source_label": "SMG1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "342132", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_ZNF774", "source_label": "ZNF774", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64399", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_HHIP", "source_label": "HHIP", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27161", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_AGO2", "source_label": "AGO2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000274585", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_RNU2-1", "source_label": "RNU2-1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26586", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CKAP2", "source_label": "CKAP2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "641517", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_DEFB109B", "source_label": "DEFB109B", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7253", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_TSHR", "source_label": "TSHR", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5362", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_PLXNA2", "source_label": "PLXNA2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5308", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_PITX2", "source_label": "PITX2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "158326", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_FREM1", "source_label": "FREM1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81839", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_VANGL1", "source_label": "VANGL1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000198984", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_MIR345", "source_label": "MIR345", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57688", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_ZSWIM6", "source_label": "ZSWIM6", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1489", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_CTF1", "source_label": "CTF1", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "126014", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_OSCAR", "source_label": "OSCAR", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "53407", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_STX18", "source_label": "STX18", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56975", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_FAM20C", "source_label": "FAM20C", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26683", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_OR4F3", "source_label": "OR4F3", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3425", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_IDUA", "source_label": "IDUA", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2626", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_GATA4", "source_label": "GATA4", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6453", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ITSN1", "source_label": "ITSN1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2257", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_FGF12", "source_label": "FGF12", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2719", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_GPC3", "source_label": "GPC3", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10150", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_MBNL2", "source_label": "MBNL2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "745", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_MYRF", "source_label": "MYRF", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26683", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_OR4F3", "source_label": "OR4F3", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000235033", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_DAAM2-AS1", "source_label": "DAAM2-AS1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6948", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_TCN2", "source_label": "TCN2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9464", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_HAND2", "source_label": "HAND2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56623", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_INPP5E", "source_label": "INPP5E", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5110", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_PCMT1", "source_label": "PCMT1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54345", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_SOX18", "source_label": "SOX18", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "639", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PRDM1", "source_label": "PRDM1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3383", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_ICAM1", "source_label": "ICAM1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5110", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_PCMT1", "source_label": "PCMT1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2200", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_FBN1", "source_label": "FBN1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9496", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_TBX4", "source_label": "TBX4", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55644", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_OSGEP", "source_label": "OSGEP", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "727857", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_BHLHA9", "source_label": "BHLHA9", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2187", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_FANCB", "source_label": "FANCB", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "50814", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_NSDHL", "source_label": "NSDHL", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9343", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_EFTUD2", "source_label": "EFTUD2", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1586", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_CYP17A1", "source_label": "CYP17A1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000255568", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_BRWD1-AS2", "source_label": "BRWD1-AS2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64288", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_ZSCAN31", "source_label": "ZSCAN31", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "253714", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_MMS22L", "source_label": "MMS22L", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6736", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_SRY", "source_label": "SRY", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3883", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_KRT33A", "source_label": "KRT33A", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23414", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_ZFPM2", "source_label": "ZFPM2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7080", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_NKX2-1", "source_label": "NKX2-1", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "740", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_MRPL49", "source_label": "MRPL49", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2626", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_GATA4", "source_label": "GATA4", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4218", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_RAB8A", "source_label": "RAB8A", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9969", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_MED13", "source_label": "MED13", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "199699", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_DAND5", "source_label": "DAND5", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5753", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_PTK6", "source_label": "PTK6", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "196513", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_DCP1B", "source_label": "DCP1B", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55012", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_PPP2R3C", "source_label": "PPP2R3C", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "92104", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_TTC30A", "source_label": "TTC30A", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4878", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_NPPA", "source_label": "NPPA", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2627", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_GATA6", "source_label": "GATA6", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6664", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SOX11", "source_label": "SOX11", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7546", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_ZIC2", "source_label": "ZIC2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27302", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_BMP10", "source_label": "BMP10", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10686", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_CLDN16", "source_label": "CLDN16", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3371", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_TNC", "source_label": "TNC", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6888", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_TALDO1", "source_label": "TALDO1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8085", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_KMT2D", "source_label": "KMT2D", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3820", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_KLRB1", "source_label": "KLRB1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9787", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_DLGAP5", "source_label": "DLGAP5", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "653", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_BMP5", "source_label": "BMP5", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91120", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_ZNF682", "source_label": "ZNF682", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4851", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_NOTCH1", "source_label": "NOTCH1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9218", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_VAPA", "source_label": "VAPA", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2737", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_GLI3", "source_label": "GLI3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2255", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_FGF10", "source_label": "FGF10", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23379", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_ICE1", "source_label": "ICE1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4617", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_MYF5", "source_label": "MYF5", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3237", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD11", "source_label": "HOXD11", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8085", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_KMT2D", "source_label": "KMT2D", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000281828", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_HERC2P7", "source_label": "HERC2P7", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5587", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PRKD1", "source_label": "PRKD1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7021", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_TFAP2B", "source_label": "TFAP2B", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "145173", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_B3GLCT", "source_label": "B3GLCT", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000232652", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_LINC02829", "source_label": "LINC02829", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91147", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_TMEM67", "source_label": "TMEM67", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55784", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_MCTP2", "source_label": "MCTP2", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000255036", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_SUGT1P4-STRA6LP-CCDC180", "source_label": "SUGT1P4-STRA6LP-CCDC180", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "440153", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_OR11H12", "source_label": "OR11H12", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84417", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_ECRG4", "source_label": "ECRG4", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4879", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_NPPB", "source_label": "NPPB", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6496", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SIX3", "source_label": "SIX3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26160", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_IFT172", "source_label": "IFT172", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "275", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_AMT", "source_label": "AMT", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54808", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_DYM", "source_label": "DYM", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000280109", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_PLAC4", "source_label": "PLAC4", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5435", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_POLR2F", "source_label": "POLR2F", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3200", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_HOXA3", "source_label": "HOXA3", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81856", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_ZNF611", "source_label": "ZNF611", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "199699", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_DAND5", "source_label": "DAND5", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6242", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_RTKN", "source_label": "RTKN", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "153478", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_PLEKHG4B", "source_label": "PLEKHG4B", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6948", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_TCN2", "source_label": "TCN2", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "994", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_CDC25B", "source_label": "CDC25B", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2253", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_FGF8", "source_label": "FGF8", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1316", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_KLF6", "source_label": "KLF6", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "635", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_BHMT", "source_label": "BHMT", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3231", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD1", "source_label": "HOXD1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "101928601", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_MEI4", "source_label": "MEI4", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2627", "relation": "Geneshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_gene-disease_GATA6", "source_label": "GATA6", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10370", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_CITED2", "source_label": "CITED2", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4607", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_MYBPC3", "source_label": "MYBPC3", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51531", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_TRMO", "source_label": "TRMO", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55558", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXNA3", "source_label": "PLXNA3", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1983", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_EIF5", "source_label": "EIF5", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57822", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_GRHL3", "source_label": "GRHL3", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000186715", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_MST1L", "source_label": "MST1L", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56180", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_MOSPD1", "source_label": "MOSPD1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10785", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_WDR4", "source_label": "WDR4", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6234", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_RPS28", "source_label": "RPS28", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2262", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_GPC5", "source_label": "GPC5", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54756", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_IL17RD", "source_label": "IL17RD", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51531", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_TRMO", "source_label": "TRMO", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84905", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_ZNF341", "source_label": "ZNF341", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6775", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_STAT4", "source_label": "STAT4", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7412", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_VCAM1", "source_label": "VCAM1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10981", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_RAB32", "source_label": "RAB32", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AP002852.1", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_AP002852.1", "source_label": "AP002852.1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51586", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MED15", "source_label": "MED15", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "283464", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_GXYLT1", "source_label": "GXYLT1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55677", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_IWS1", "source_label": "IWS1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1859", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_DYRK1A", "source_label": "DYRK1A", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "286464", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_CFAP47", "source_label": "CFAP47", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8576", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_STK16", "source_label": "STK16", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "149465", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CFAP57", "source_label": "CFAP57", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5532", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_PPP3CB", "source_label": "PPP3CB", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11155", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_LDB3", "source_label": "LDB3", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29801", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_ZDHHC8", "source_label": "ZDHHC8", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2697", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_GJA1", "source_label": "GJA1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000207827", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_MIR30A", "source_label": "MIR30A", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "131405", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_TRIM71", "source_label": "TRIM71", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2657", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_GDF1", "source_label": "GDF1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51626", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_DYNC2LI1", "source_label": "DYNC2LI1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4345", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CD200", "source_label": "CD200", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9546", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_APBA3", "source_label": "APBA3", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4602", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_MYB", "source_label": "MYB", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "348", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_APOE", "source_label": "APOE", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2618", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_GART", "source_label": "GART", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84976", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_DISP1", "source_label": "DISP1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3720", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_JARID2", "source_label": "JARID2", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1947", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_EFNB1", "source_label": "EFNB1", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5781", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_PTPN11", "source_label": "PTPN11", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000106133", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_NSUN5P2", "source_label": "NSUN5P2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000265924", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_MIR5692C1", "source_label": "MIR5692C1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22797", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_TFEC", "source_label": "TFEC", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2294", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_FOXF1", "source_label": "FOXF1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "658", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_BMPR1B", "source_label": "BMPR1B", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4223", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_MEOX2", "source_label": "MEOX2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC124248.1", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_AC124248.1", "source_label": "AC124248.1", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "94026", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_POM121L2", "source_label": "POM121L2", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23322", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_RPGRIP1L", "source_label": "RPGRIP1L", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7030", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_TFE3", "source_label": "TFE3", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2736", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_GLI2", "source_label": "GLI2", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11149", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_BVES", "source_label": "BVES", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3980", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_LIG3", "source_label": "LIG3", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5362", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_PLXNA2", "source_label": "PLXNA2", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6469", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_SHH", "source_label": "SHH", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7478", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_WNT8A", "source_label": "WNT8A", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6604", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_SMARCD3", "source_label": "SMARCD3", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11129", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CLASRP", "source_label": "CLASRP", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4656", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_MYOG", "source_label": "MYOG", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "174", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_AFP", "source_label": "AFP", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54903", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_MKS1", "source_label": "MKS1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC116345.3", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_AC116345.3", "source_label": "AC116345.3", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "282996", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_RBM20", "source_label": "RBM20", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5083", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_PAX9", "source_label": "PAX9", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7022", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_TFAP2C", "source_label": "TFAP2C", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7084", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TK2", "source_label": "TK2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57553", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_MICAL3", "source_label": "MICAL3", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "89910", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_UBE3B", "source_label": "UBE3B", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7290", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_HIRA", "source_label": "HIRA", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7478", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_WNT8A", "source_label": "WNT8A", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "130574", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_LYPD6", "source_label": "LYPD6", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2966", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_GTF2H2", "source_label": "GTF2H2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26257", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_NKX2-8", "source_label": "NKX2-8", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27086", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_FOXP1", "source_label": "FOXP1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1719", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_DHFR", "source_label": "DHFR", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3178", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_HNRNPA1", "source_label": "HNRNPA1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84342", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_COG8", "source_label": "COG8", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4205", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_MEF2A", "source_label": "MEF2A", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000238184", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_CD81-AS1", "source_label": "CD81-AS1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23322", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_RPGRIP1L", "source_label": "RPGRIP1L", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1513", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_CTSK", "source_label": "CTSK", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51715", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_RAB23", "source_label": "RAB23", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29926", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_GMPPA", "source_label": "GMPPA", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79575", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ABHD8", "source_label": "ABHD8", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8928", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_FOXH1", "source_label": "FOXH1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "596", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_BCL2", "source_label": "BCL2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "58476", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_TP53INP2", "source_label": "TP53INP2", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10892", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_MALT1", "source_label": "MALT1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC008132.1", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_AC008132.1", "source_label": "AC008132.1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1948", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_EFNB2", "source_label": "EFNB2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5566", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_PRKACA", "source_label": "PRKACA", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2153", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_F5", "source_label": "F5", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5093", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_PCBP1", "source_label": "PCBP1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6450", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_SH3BGR", "source_label": "SH3BGR", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7290", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_HIRA", "source_label": "HIRA", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3313", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_HSPA9", "source_label": "HSPA9", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "56853", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_CELF4", "source_label": "CELF4", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64327", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_LMBR1", "source_label": "LMBR1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6444", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_SGCD", "source_label": "SGCD", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "25970", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_SH2B1", "source_label": "SH2B1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000215417", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_MIR17HG", "source_label": "MIR17HG", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4036", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_LRP2", "source_label": "LRP2", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6496", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_SIX3", "source_label": "SIX3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54361", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_WNT4", "source_label": "WNT4", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54836", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_BSPRY", "source_label": "BSPRY", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4624", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_MYH6", "source_label": "MYH6", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2300", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_FOXL1", "source_label": "FOXL1", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29886", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_SNX8", "source_label": "SNX8", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3234", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXD8", "source_label": "HOXD8", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000198974", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MIR30E", "source_label": "MIR30E", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "119467", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_CLRN3", "source_label": "CLRN3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6448", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_SGSH", "source_label": "SGSH", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54836", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_BSPRY", "source_label": "BSPRY", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3670", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_ISL1", "source_label": "ISL1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1028", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_CDKN1C", "source_label": "CDKN1C", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4772", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_NFATC1", "source_label": "NFATC1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55668", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_GPATCH2L", "source_label": "GPATCH2L", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "127294", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_MYOM3", "source_label": "MYOM3", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000199990", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_VTRNA1-1", "source_label": "VTRNA1-1", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4524", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_MTHFR", "source_label": "MTHFR", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6236", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_RRAD", "source_label": "RRAD", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "182", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_JAG1", "source_label": "JAG1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55798", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_METTL2B", "source_label": "METTL2B", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "55997", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_CFC1", "source_label": "CFC1", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6608", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_SMO", "source_label": "SMO", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26249", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_KLHL3", "source_label": "KLHL3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2350", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_FOLR2", "source_label": "FOLR2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "92002", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_CCNQ", "source_label": "CCNQ", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51293", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_CD320", "source_label": "CD320", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9782", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MATR3", "source_label": "MATR3", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91057", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_CCDC34", "source_label": "CCDC34", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2626", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_GATA4", "source_label": "GATA4", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "114791", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_TUBGCP5", "source_label": "TUBGCP5", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "342132", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_ZNF774", "source_label": "ZNF774", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4535", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_MT-ND1", "source_label": "MT-ND1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "140628", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_GATA5", "source_label": "GATA5", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8646", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_CHRD", "source_label": "CHRD", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2952", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_GSTT1", "source_label": "GSTT1", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7410", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_VAV2", "source_label": "VAV2", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9096", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_TBX18", "source_label": "TBX18", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9350", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_CER1", "source_label": "CER1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9118", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_INA", "source_label": "INA", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "649", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_BMP1", "source_label": "BMP1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "90627", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_STARD13", "source_label": "STARD13", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "79295", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_OR5H6", "source_label": "OR5H6", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4837", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_NNMT", "source_label": "NNMT", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC093614.1", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_AC093614.1", "source_label": "AC093614.1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "653509", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_SFTPA1", "source_label": "SFTPA1", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "158135", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_TTLL11", "source_label": "TTLL11", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "183", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_AGT", "source_label": "AGT", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "128371", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_OR6K6", "source_label": "OR6K6", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4613", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_MYCN", "source_label": "MYCN", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5435", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_POLR2F", "source_label": "POLR2F", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23384", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_SPECC1L", "source_label": "SPECC1L", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "AC090061.1", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_AC090061.1", "source_label": "AC090061.1", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8871", "relation": "Geneshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_gene-disease_SYNJ2", "source_label": "SYNJ2", "target_label": "Single ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10943", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_MSL3", "source_label": "MSL3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1956", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_EGFR", "source_label": "EGFR", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7140", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_TNNT3", "source_label": "TNNT3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5176", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_SERPINF1", "source_label": "SERPINF1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2200", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_FBN1", "source_label": "FBN1", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6663", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_SOX10", "source_label": "SOX10", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "10154", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXNC1", "source_label": "PLXNC1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1482", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_NKX2-5", "source_label": "NKX2-5", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54756", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_IL17RD", "source_label": "IL17RD", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23432", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_GPR161", "source_label": "GPR161", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "344901", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_OSTN", "source_label": "OSTN", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "63929", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_XPNPEP3", "source_label": "XPNPEP3", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1401", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_CRP", "source_label": "CRP", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80184", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_CEP290", "source_label": "CEP290", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2736", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_GLI2", "source_label": "GLI2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "51259", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_TMEM216", "source_label": "TMEM216", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000266589", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_MIR4512", "source_label": "MIR4512", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6929", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_TCF3", "source_label": "TCF3", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5130", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_PCYT1A", "source_label": "PCYT1A", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4654", "relation": "Geneshot", "target": "HP:0000528", "properties": { "id": "Anophthalmia_gene-disease_MYOD1", "source_label": "MYOD1", "target_label": "Anophthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5553", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_PRG2", "source_label": "PRG2", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1464", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_CSPG4", "source_label": "CSPG4", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9247", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_GCM2", "source_label": "GCM2", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "27086", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_FOXP1", "source_label": "FOXP1", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000255568", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_BRWD1-AS2", "source_label": "BRWD1-AS2", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3228", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_HOXC12", "source_label": "HOXC12", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7439", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_BEST1", "source_label": "BEST1", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11023", "relation": "Geneshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_gene-disease_VAX1", "source_label": "VAX1", "target_label": "Cleft palate", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "54866", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_PPP1R14D", "source_label": "PPP1R14D", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4524", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_MTHFR", "source_label": "MTHFR", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9394", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_HS6ST1", "source_label": "HS6ST1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23111", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_SPART", "source_label": "SPART", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "80776", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_B9D2", "source_label": "B9D2", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6529", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_SLC6A1", "source_label": "SLC6A1", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2001", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ELF5", "source_label": "ELF5", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000276622", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_MIR6499", "source_label": "MIR6499", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "53834", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_FGFRL1", "source_label": "FGFRL1", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83732", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_RIOK1", "source_label": "RIOK1", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4867", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_NPHP1", "source_label": "NPHP1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "150572", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_SMYD1", "source_label": "SMYD1", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11023", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_VAX1", "source_label": "VAX1", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9782", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_MATR3", "source_label": "MATR3", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7547", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_ZIC3", "source_label": "ZIC3", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000265507", "relation": "Geneshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_gene-disease_MIR4435-1", "source_label": "MIR4435-1", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "147912", "relation": "Geneshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_gene-disease_SIX5", "source_label": "SIX5", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "151126", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_ZNF385B", "source_label": "ZNF385B", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "132884", "relation": "Geneshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_gene-disease_EVC2", "source_label": "EVC2", "target_label": "Encephalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "340665", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_CYP26C1", "source_label": "CYP26C1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3229", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_HOXC13", "source_label": "HOXC13", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "123606", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_NIPA1", "source_label": "NIPA1", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5754", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_PTK7", "source_label": "PTK7", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "349149", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_GJC3", "source_label": "GJC3", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84987", "relation": "Geneshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_gene-disease_COX14", "source_label": "COX14", "target_label": "Coarctation of aorta", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2125", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_EVPL", "source_label": "EVPL", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2736", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_GLI2", "source_label": "GLI2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "9465", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_AKAP7", "source_label": "AKAP7", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1404", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_HAPLN1", "source_label": "HAPLN1", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4522", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_MTHFD1", "source_label": "MTHFD1", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "11052", "relation": "Geneshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_gene-disease_CPSF6", "source_label": "CPSF6", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "945", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_CD33", "source_label": "CD33", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5396", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_PRRX1", "source_label": "PRRX1", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6997", "relation": "Geneshot", "target": "HP:0031348", "properties": { "id": "Dextrotransposition of the great arteries_gene-disease_TDGF1", "source_label": "TDGF1", "target_label": "Dextrotransposition of the great arteries", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1544", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_CYP1A2", "source_label": "CYP1A2", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7809", "relation": "Geneshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_gene-disease_BSND", "source_label": "BSND", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000304169", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_ENSP00000304169", "source_label": "ENSP00000304169", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4879", "relation": "Geneshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_gene-disease_NPPB", "source_label": "NPPB", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "FO681492.1", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_FO681492.1", "source_label": "FO681492.1", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "57336", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_ZNF287", "source_label": "ZNF287", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "81037", "relation": "Geneshot", "target": "HP:0410030", "properties": { "id": "Cleft lip_gene-disease_CLPTM1L", "source_label": "CLPTM1L", "target_label": "Cleft lip", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "357", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_SHROOM2", "source_label": "SHROOM2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "650", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_BMP2", "source_label": "BMP2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "794", "relation": "Geneshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_gene-disease_CALB2", "source_label": "CALB2", "target_label": "Omphalocele", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSP00000480893", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ENSP00000480893", "source_label": "ENSP00000480893", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64093", "relation": "Geneshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_gene-disease_SMOC1", "source_label": "SMOC1", "target_label": "Talipes equinovarus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5095", "relation": "Geneshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_gene-disease_PCCA", "source_label": "PCCA", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6205", "relation": "Geneshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_gene-disease_RPS11", "source_label": "RPS11", "target_label": "Truncus arteriosus", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "23161", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_SNX13", "source_label": "SNX13", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "64601", "relation": "Geneshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_gene-disease_VPS16", "source_label": "VPS16", "target_label": "Abnormality of limbs", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2784", "relation": "Geneshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_gene-disease_GNB3", "source_label": "GNB3", "target_label": "Gastroschisis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "2321", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_FLT1", "source_label": "FLT1", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6222", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_RPS18", "source_label": "RPS18", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "26017", "relation": "Geneshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_gene-disease_FAM32A", "source_label": "FAM32A", "target_label": "Esophageal atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6016", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_RIT1", "source_label": "RIT1", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "8038", "relation": "Geneshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_gene-disease_ADAM12", "source_label": "ADAM12", "target_label": "Trisomy 13", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "4254", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_KITLG", "source_label": "KITLG", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "191", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_AHCY", "source_label": "AHCY", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "6910", "relation": "Geneshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_gene-disease_TBX5", "source_label": "TBX5", "target_label": "Tricuspid atresia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "83723", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_TLCD3B", "source_label": "TLCD3B", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "127540", "relation": "Geneshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_gene-disease_HMGB4", "source_label": "HMGB4", "target_label": "Anencephaly", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "3955", "relation": "Geneshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_gene-disease_LFNG", "source_label": "LFNG", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "84295", "relation": "Geneshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_gene-disease_PHF6", "source_label": "PHF6", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "91584", "relation": "Geneshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_gene-disease_PLXNA4", "source_label": "PLXNA4", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "7392", "relation": "Geneshot", "target": "HP:0000568", "properties": { "id": "Microphthalmia_gene-disease_USF2", "source_label": "USF2", "target_label": "Microphthalmia", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "29982", "relation": "Geneshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_gene-disease_NRBF2", "source_label": "NRBF2", "target_label": "Spina bifida", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "22797", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_TFEC", "source_label": "TFEC", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000262001", "relation": "Geneshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_gene-disease_DLGAP1-AS2", "source_label": "DLGAP1-AS2", "target_label": "Trisomy 18", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "ENSG00000260551", "relation": "Geneshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_gene-disease_PWRN2", "source_label": "PWRN2", "target_label": "Down syndrome", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "5781", "relation": "Geneshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_gene-disease_PTPN11", "source_label": "PTPN11", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "1717", "relation": "Geneshot", "target": "HP:0001642", "properties": { "id": "Pulmonic stenosis_gene-disease_DHCR7", "source_label": "DHCR7", "target_label": "Pulmonic stenosis", "directed": true, "resource": "Geneshot" } }, { "type": "Relation", "source": "CID:2127", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_N-(4-Hydroxyphenyl)icosa-5,8,11,14-tetraenamide", "source_label": "N-(4-Hydroxyphenyl)icosa-5,8,11,14-tetraenamide", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3973", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_LY-294002", "source_label": "LY-294002", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4932", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Propafenone", "source_label": "Propafenone", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:7029", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Diethylpropion", "source_label": "Diethylpropion", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3680", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Dexamethasone 21-acetate", "source_label": "Dexamethasone 21-acetate", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5472", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Ticlopidine", "source_label": "Ticlopidine", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4197", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Milrinone", "source_label": "Milrinone", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2585", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Carvedilol", "source_label": "Carvedilol", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:54117", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_DSSTOX_CID_2640", "source_label": "DSSTOX_CID_2640", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362032", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2803", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Clonidine", "source_label": "Clonidine", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:171548", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Biotin", "source_label": "Biotin", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3779", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Levisoprenaline", "source_label": "Levisoprenaline", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:149351", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Alista", "source_label": "Alista", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC04521755", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_ZINC04521755", "source_label": "ZINC04521755", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362032", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:12801781", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_SCHEMBL4098081", "source_label": "SCHEMBL4098081", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:71329", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Dofetilide", "source_label": "Dofetilide", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2153", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Theophylline", "source_label": "Theophylline", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1352", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_H7", "source_label": "H7", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3730", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Iohexol", "source_label": "Iohexol", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC03881699", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_ZINC03881699", "source_label": "ZINC03881699", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2651", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_SPBIO_002278", "source_label": "SPBIO_002278", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:23760137", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_PRESTWICK3_000866", "source_label": "PRESTWICK3_000866", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:60838", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Irinotecan", "source_label": "Irinotecan", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-6061", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_LSM-6061", "source_label": "LSM-6061", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2551", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Carbachol Chloride", "source_label": "Carbachol Chloride", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2551", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Carbachol Chloride", "source_label": "Carbachol Chloride", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2733335", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Streptozotocin", "source_label": "Streptozotocin", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5493444", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Aliskiren", "source_label": "Aliskiren", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3793", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Itrazole", "source_label": "Itrazole", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:57369718", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_BRD-K61341215-004-01-2", "source_label": "BRD-K61341215-004-01-2", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3899", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Leflunomide", "source_label": "Leflunomide", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4272", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid", "source_label": "6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3157", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Doxazosin", "source_label": "Doxazosin", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4740", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Pentoxifylline", "source_label": "Pentoxifylline", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2405", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Bisoprolol", "source_label": "Bisoprolol", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4168", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Metoclopramide", "source_label": "Metoclopramide", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1893", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_7-Nitroindazole", "source_label": "7-Nitroindazole", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2803", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Clonidine", "source_label": "Clonidine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:31072", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Carbimazole", "source_label": "Carbimazole", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4091", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Metformin", "source_label": "Metformin", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2512", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_NCGC00167821-01", "source_label": "NCGC00167821-01", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1691", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_NSC169534", "source_label": "NSC169534", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2022", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Acyclovir", "source_label": "Acyclovir", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3121", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Valproic acid", "source_label": "Valproic acid", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1071", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_9-Cis retinol", "source_label": "9-Cis retinol", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362032", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:200", "relation": "Drugshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_IN1541", "source_label": "IN1541", "target_label": "Down syndrome", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5602", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_IN1048", "source_label": "IN1048", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1986", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Acetazolamide", "source_label": "Acetazolamide", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC03977919", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_ZINC03977919", "source_label": "ZINC03977919", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", 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"target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2471", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Bumetanide", "source_label": "Bumetanide", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2471", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Bumetanide", "source_label": "Bumetanide", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:31072", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Carbimazole", "source_label": "Carbimazole", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:45006157", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Altrenogest", "source_label": "Altrenogest", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:149351", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Alista", "source_label": "Alista", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:42617", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid", "source_label": "(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2284", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Baclofen", "source_label": "Baclofen", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5920", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Liothyronine", "source_label": "Liothyronine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2153", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Theophylline", "source_label": "Theophylline", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3973", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_LY-294002", "source_label": "LY-294002", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2148", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Aminohippuric acid", "source_label": "Aminohippuric acid", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0001669", "properties": { 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"Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3059", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Diflunisal", "source_label": "Diflunisal", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:200", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_IN1541", "source_label": "IN1541", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:175540", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Esatenolol", "source_label": "Esatenolol", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:149351", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Alista", "source_label": "Alista", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707547", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_BRD-K66198023-237-01-9", "source_label": "BRD-K66198023-237-01-9", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4906", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Prilocaine", "source_label": "Prilocaine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2796", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Clofibrate", "source_label": "Clofibrate", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1775", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Phenytoin", "source_label": "Phenytoin", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:9819467", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_N-Methylparoxetine", "source_label": "N-Methylparoxetine", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3736", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Iopromide", "source_label": "Iopromide", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2651", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_SPBIO_002278", "source_label": "SPBIO_002278", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:60953", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Capecitabine", "source_label": "Capecitabine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6741", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Methylprednisolone", "source_label": "Methylprednisolone", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1986", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Acetazolamide", "source_label": "Acetazolamide", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:11892032", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Epiisopicropodophyllin", "source_label": "Epiisopicropodophyllin", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2153", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Theophylline", "source_label": "Theophylline", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:451668", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Decitabine", "source_label": "Decitabine", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5742673", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Cefotaxime", "source_label": "Cefotaxime", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2713", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Chlorhexidine", "source_label": "Chlorhexidine", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3016", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Diazepam", "source_label": "Diazepam", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707468", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_LSM-6041", "source_label": "LSM-6041", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707458", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_BRD-K55113501-001-01-2", "source_label": "BRD-K55113501-001-01-2", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC03977919", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_ZINC03977919", "source_label": "ZINC03977919", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:27447", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Cephalexin", "source_label": "Cephalexin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3033", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Diclofenac", "source_label": "Diclofenac", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC04521755", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_ZINC04521755", "source_label": "ZINC04521755", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3680", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Dexamethasone 21-acetate", "source_label": "Dexamethasone 21-acetate", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6741", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Methylprednisolone", "source_label": "Methylprednisolone", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:123631", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Gefitinib", "source_label": "Gefitinib", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:44118238", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Cyclopamine", "source_label": "Cyclopamine", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2549", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Capsazepine", "source_label": "Capsazepine", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4506", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Nitrazepam", "source_label": "Nitrazepam", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:564", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Aminocaproic acid", "source_label": "Aminocaproic acid", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1775", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Phenytoin", "source_label": "Phenytoin", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:33613", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Amoxicillin", "source_label": "Amoxicillin", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:33613", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Amoxicillin", "source_label": "Amoxicillin", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:45006158", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Betamethasone", "source_label": "Betamethasone", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3157", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Doxazosin", "source_label": "Doxazosin", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3157", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Doxazosin", "source_label": "Doxazosin", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2391", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Bisacodyl", "source_label": "Bisacodyl", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5320346", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Hydrocortisone", "source_label": "Hydrocortisone", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:9811704", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Acarbose", "source_label": "Acarbose", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5212", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Sildenafil", "source_label": "Sildenafil", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707474", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_BRD-K72853990-066-01-3", "source_label": "BRD-K72853990-066-01-3", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:149351", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Alista", "source_label": "Alista", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5819", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Levothyroxine", "source_label": "Levothyroxine", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6710622", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_SPECTRUM_000281", "source_label": "SPECTRUM_000281", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707413", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_BRD-K46503544-001-01-5", "source_label": "BRD-K46503544-001-01-5", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1218", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_SKF 81297", "source_label": "SKF 81297", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1352", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_H7", "source_label": "H7", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:7048568", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_AC1OFCDP", "source_label": "AC1OFCDP", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4104", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Methimazole", "source_label": "Methimazole", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC04521755", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_ZINC04521755", "source_label": "ZINC04521755", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:65492", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Iopamidol", "source_label": "Iopamidol", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5212", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Sildenafil", "source_label": "Sildenafil", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3365", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Fluconazole", "source_label": "Fluconazole", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:10861069", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Estropipate", "source_label": "Estropipate", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5376", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_SPECTRUM_001028", "source_label": "SPECTRUM_001028", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3385", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Fluorouracil", "source_label": "Fluorouracil", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:40469463", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_AJ-47563", "source_label": "AJ-47563", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2405", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Bisoprolol", "source_label": "Bisoprolol", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:45006158", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Betamethasone", "source_label": "Betamethasone", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-6064", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_LSM-6064", "source_label": "LSM-6064", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5819", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Levothyroxine", "source_label": "Levothyroxine", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-4344", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_LSM-4344", "source_label": "LSM-4344", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4302962", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_AM 281", "source_label": "AM 281", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362032", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:14900", "relation": "Drugshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Glycerol Monopalmitate", "source_label": "Glycerol Monopalmitate", "target_label": "Down syndrome", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2333", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Benzbromarone", "source_label": "Benzbromarone", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:854019", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Cotinine", "source_label": "Cotinine", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5917", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Pentylenetetrazol", "source_label": "Pentylenetetrazol", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:123630", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Tazobactam", "source_label": "Tazobactam", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2907", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Cyclophosphamide", "source_label": "Cyclophosphamide", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5327", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Sulfamethazine", "source_label": "Sulfamethazine", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC03881699", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_ZINC03881699", "source_label": "ZINC03881699", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2022", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Acyclovir", "source_label": "Acyclovir", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2803", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Clonidine", "source_label": "Clonidine", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1691", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_NSC169534", "source_label": "NSC169534", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3598", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Hexachlorophene", "source_label": "Hexachlorophene", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5742673", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Cefotaxime", "source_label": "Cefotaxime", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:31072", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Carbimazole", "source_label": "Carbimazole", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:198107", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_L-Cis-Diltiazem", "source_label": "L-Cis-Diltiazem", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707466", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_BRD-K40476324-001-01-6", "source_label": "BRD-K40476324-001-01-6", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2585", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Carvedilol", "source_label": "Carvedilol", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:171548", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Biotin", "source_label": "Biotin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16231", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Amiloride", "source_label": "Amiloride", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:23760137", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_PRESTWICK3_000866", "source_label": "PRESTWICK3_000866", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3958", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Lorazepam", "source_label": "Lorazepam", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2405", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Bisoprolol", "source_label": "Bisoprolol", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6741", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Methylprednisolone", "source_label": "Methylprednisolone", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707413", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_BRD-K46503544-001-01-5", "source_label": "BRD-K46503544-001-01-5", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1691", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_NSC169534", "source_label": "NSC169534", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4197", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Milrinone", "source_label": "Milrinone", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:34359", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Carbidopa", "source_label": "Carbidopa", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:78441492", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_LSM-5108", "source_label": "LSM-5108", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3878", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Lamotrigine", "source_label": "Lamotrigine", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2907", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Cyclophosphamide", "source_label": "Cyclophosphamide", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2088", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Alendronic acid", "source_label": "Alendronic acid", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:54688261", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_(S)-(-)-Warfarin", "source_label": "(S)-(-)-Warfarin", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:564", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Aminocaproic acid", "source_label": "Aminocaproic acid", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16231", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Amiloride", "source_label": "Amiloride", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3730", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Iohexol", "source_label": "Iohexol", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3730", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Iohexol", "source_label": "Iohexol", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1352", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_H7", "source_label": "H7", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4506", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Nitrazepam", "source_label": "Nitrazepam", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:7048624", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_AC1OFCH7", "source_label": "AC1OFCH7", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:854019", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Cotinine", "source_label": "Cotinine", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3779", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Levisoprenaline", "source_label": "Levisoprenaline", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:119376", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_GR 113808", "source_label": "GR 113808", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5493444", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Aliskiren", "source_label": "Aliskiren", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1983", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Acetaminophen", "source_label": "Acetaminophen", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5538", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Vitinoin", "source_label": "Vitinoin", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2082", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Albendazole", "source_label": "Albendazole", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707474", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_BRD-K72853990-066-01-3", "source_label": "BRD-K72853990-066-01-3", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3690", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Ifosfamide", "source_label": "Ifosfamide", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:44483336", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Fluticasone", "source_label": "Fluticasone", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:171548", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Biotin", "source_label": "Biotin", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1775", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Phenytoin", "source_label": "Phenytoin", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:31072", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Carbimazole", "source_label": "Carbimazole", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707458", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_BRD-K55113501-001-01-2", "source_label": "BRD-K55113501-001-01-2", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:33613", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Amoxicillin", "source_label": "Amoxicillin", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5320346", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Hydrocortisone", "source_label": "Hydrocortisone", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3108", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Dipyridamole", "source_label": "Dipyridamole", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-6049", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_LSM-6049", "source_label": "LSM-6049", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3730", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Iohexol", "source_label": "Iohexol", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2512", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_NCGC00167821-01", "source_label": "NCGC00167821-01", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2551", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Carbachol Chloride", "source_label": "Carbachol Chloride", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3680", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Dexamethasone 21-acetate", "source_label": "Dexamethasone 21-acetate", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2327", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Benserazide", "source_label": "Benserazide", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2585", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Carvedilol", "source_label": "Carvedilol", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:176870", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Erlotinib", "source_label": "Erlotinib", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC03977919", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_ZINC03977919", "source_label": "ZINC03977919", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5742673", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Cefotaxime", "source_label": "Cefotaxime", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:564", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Aminocaproic acid", "source_label": "Aminocaproic acid", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:34312", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Oxcarbazepine", "source_label": "Oxcarbazepine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3016", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Diazepam", "source_label": "Diazepam", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:42617", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid", "source_label": "(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2022", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Acyclovir", "source_label": "Acyclovir", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2651", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_SPBIO_002278", "source_label": "SPBIO_002278", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-4788", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_LSM-4788", "source_label": "LSM-4788", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:50599", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Didanosine", "source_label": "Didanosine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2141", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Amifostine", "source_label": "Amifostine", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5538", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Vitinoin", "source_label": "Vitinoin", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4943", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Propofol", "source_label": "Propofol", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC04521755", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_ZINC04521755", "source_label": "ZINC04521755", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3019", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Diazoxide", "source_label": "Diazoxide", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:54676537", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Acenocoumarol", "source_label": "Acenocoumarol", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3779", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Levisoprenaline", "source_label": "Levisoprenaline", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1986", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_Acetazolamide", "source_label": "Acetazolamide", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4104", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Methimazole", "source_label": "Methimazole", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707547", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_BRD-K66198023-237-01-9", "source_label": "BRD-K66198023-237-01-9", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2512", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_NCGC00167821-01", "source_label": "NCGC00167821-01", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2478", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Busulfan", "source_label": "Busulfan", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:60953", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Capecitabine", "source_label": "Capecitabine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3547", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Fasudil", "source_label": "Fasudil", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3291", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Ethosuximide", "source_label": "Ethosuximide", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:41317", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_9-Cis acitretin", "source_label": "9-Cis acitretin", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4197", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Milrinone", "source_label": "Milrinone", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:45006158", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Betamethasone", "source_label": "Betamethasone", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6128", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Androstenedione", "source_label": "Androstenedione", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1071", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_9-Cis retinol", "source_label": "9-Cis retinol", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3121", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Valproic acid", "source_label": "Valproic acid", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4909", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Primidone", "source_label": "Primidone", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:887", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_(+)-Camptothecin", "source_label": "(+)-Camptothecin", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC43409584", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_ZINC43409584", "source_label": "ZINC43409584", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6710657", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_SPECTRUM_001020", "source_label": "SPECTRUM_001020", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3878", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Lamotrigine", "source_label": "Lamotrigine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:ZINC04521755", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_ZINC04521755", "source_label": "ZINC04521755", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4272", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid", "source_label": "6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4668801", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_448906-42-1", "source_label": "448906-42-1", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6128", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Androstenedione", "source_label": "Androstenedione", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2585", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Carvedilol", "source_label": "Carvedilol", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:31072", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Carbimazole", "source_label": "Carbimazole", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3016", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Diazepam", "source_label": "Diazepam", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3276", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Etanidazole", "source_label": "Etanidazole", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707470", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_ZINC95486475", "source_label": "ZINC95486475", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5212", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Sildenafil", "source_label": "Sildenafil", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2153", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Theophylline", "source_label": "Theophylline", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1456", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Odq", "source_label": "Odq", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:298", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Chloromycetny", "source_label": "Chloromycetny", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1775", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Phenytoin", "source_label": "Phenytoin", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-2581", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_LSM-2581", "source_label": "LSM-2581", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2082", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Albendazole", "source_label": "Albendazole", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3356", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Flecainide", "source_label": "Flecainide", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3121", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Valproic acid", "source_label": "Valproic acid", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3373", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Flumazenil", "source_label": "Flumazenil", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2764", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Ciprofloxacin", "source_label": "Ciprofloxacin", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2801", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Clomipramine", "source_label": "Clomipramine", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:222786", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Cortisone", "source_label": "Cortisone", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707483", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_ZINC43393638", "source_label": "ZINC43393638", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2764", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Ciprofloxacin", "source_label": "Ciprofloxacin", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5920", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Liothyronine", "source_label": "Liothyronine", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1830", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_IN1451", "source_label": "IN1451", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16231", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Amiloride", "source_label": "Amiloride", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2390", "relation": "Drugshot", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_IN1436", "source_label": "IN1436", "target_label": "Down syndrome", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:60795", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Aripiprazole", "source_label": "Aripiprazole", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4932", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Propafenone", "source_label": "Propafenone", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5920", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Liothyronine", "source_label": "Liothyronine", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:41317", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_9-Cis acitretin", "source_label": "9-Cis acitretin", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3054", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_(Z,E)-Diethylstilbestrol", "source_label": "(Z,E)-Diethylstilbestrol", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3100", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Diphenhydramine", "source_label": "Diphenhydramine", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1673", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_3-Methyladenine", "source_label": "3-Methyladenine", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-6053", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_LSM-6053", "source_label": "LSM-6053", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4044", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Mefenamic acid", "source_label": "Mefenamic acid", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2082", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Albendazole", "source_label": "Albendazole", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2370", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Bethanechol", "source_label": "Bethanechol", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:171548", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Biotin", "source_label": "Biotin", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3736", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Iopromide", "source_label": "Iopromide", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3016", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Diazepam", "source_label": "Diazepam", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2662", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Celecoxib", "source_label": "Celecoxib", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2764", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Ciprofloxacin", "source_label": "Ciprofloxacin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3680", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Dexamethasone 21-acetate", "source_label": "Dexamethasone 21-acetate", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2160", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Amitriptyline", "source_label": "Amitriptyline", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2541", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Candesartan", "source_label": "Candesartan", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2370", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Bethanechol", "source_label": "Bethanechol", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:175540", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Esatenolol", "source_label": "Esatenolol", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2895", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Cyclobenzaprine", "source_label": "Cyclobenzaprine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:149351", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Alista", "source_label": "Alista", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362032", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:34359", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Carbidopa", "source_label": "Carbidopa", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1986", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_Acetazolamide", "source_label": "Acetazolamide", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2174", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5212", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Sildenafil", "source_label": "Sildenafil", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5917", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Pentylenetetrazol", "source_label": "Pentylenetetrazol", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:171548", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Biotin", "source_label": "Biotin", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:31072", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Carbimazole", "source_label": "Carbimazole", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707474", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_BRD-K72853990-066-01-3", "source_label": "BRD-K72853990-066-01-3", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5426", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Thalidomide", "source_label": "Thalidomide", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3385", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Fluorouracil", "source_label": "Fluorouracil", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:441401", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_Linezolid", "source_label": "Linezolid", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2118", "relation": "Drugshot", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Alprazolam", "source_label": "Alprazolam", "target_label": "Gastroschisis", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3454", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Ganciclovir", "source_label": "Ganciclovir", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2764", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Ciprofloxacin", "source_label": "Ciprofloxacin", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3736", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Iopromide", "source_label": "Iopromide", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:197712", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_CHEMBL302753", "source_label": "CHEMBL302753", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2333", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Benzbromarone", "source_label": "Benzbromarone", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3019", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Diazoxide", "source_label": "Diazoxide", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:44118238", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Cyclopamine", "source_label": "Cyclopamine", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-5725", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_LSM-5725", "source_label": "LSM-5725", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4943", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Propofol", "source_label": "Propofol", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4534086", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_NCGC00025073-01", "source_label": "NCGC00025073-01", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1691", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_NSC169534", "source_label": "NSC169534", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5376", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_SPECTRUM_001028", "source_label": "SPECTRUM_001028", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1983", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Acetaminophen", "source_label": "Acetaminophen", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5742673", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Cefotaxime", "source_label": "Cefotaxime", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:12810432", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_ZINC3830447", "source_label": "ZINC3830447", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3559", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Haloperidol", "source_label": "Haloperidol", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707474", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_BRD-K72853990-066-01-3", "source_label": "BRD-K72853990-066-01-3", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:65492", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Iopamidol", "source_label": "Iopamidol", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:41317", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_9-Cis acitretin", "source_label": "9-Cis acitretin", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:171548", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Biotin", "source_label": "Biotin", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:44118238", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Cyclopamine", "source_label": "Cyclopamine", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3033", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Diclofenac", "source_label": "Diclofenac", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2803", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Clonidine", "source_label": "Clonidine", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:33613", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Amoxicillin", "source_label": "Amoxicillin", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2585", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Carvedilol", "source_label": "Carvedilol", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2554", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:33613", "relation": "Drugshot", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Amoxicillin", "source_label": "Amoxicillin", "target_label": "Spina bifida", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362119", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Lisinopril", "source_label": "Lisinopril", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:135398745", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Olanzapine", "source_label": "Olanzapine", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3121", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Valproic acid", "source_label": "Valproic acid", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:441289", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Pancuronium", "source_label": "Pancuronium", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1691", "relation": "Drugshot", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_NSC169534", "source_label": "NSC169534", "target_label": "Anencephaly", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:59768", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Esmolol", "source_label": "Esmolol", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2551", "relation": "Drugshot", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Carbachol Chloride", "source_label": "Carbachol Chloride", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6918540", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Dalcetrapib", "source_label": "Dalcetrapib", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2187", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Anastrozole", "source_label": "Anastrozole", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3779", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Levisoprenaline", "source_label": "Levisoprenaline", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:323", "relation": "Drugshot", "target": "HP:0010316", "properties": { "id": "Ebstein anomaly of the tricuspid valve_chemical-disease_Coumarin", "source_label": "Coumarin", "target_label": "Ebstein anomaly of the tricuspid valve", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2405", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Bisoprolol", "source_label": "Bisoprolol", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4044", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Mefenamic acid", "source_label": "Mefenamic acid", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:64139", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Efavirenz", "source_label": "Efavirenz", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3108", "relation": "Drugshot", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Dipyridamole", "source_label": "Dipyridamole", "target_label": "Hypoplastic left heart", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2519", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3016", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Diazepam", "source_label": "Diazepam", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:21138", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Dexpropranolol", "source_label": "Dexpropranolol", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:39912", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Dexibuprofen", "source_label": "Dexibuprofen", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:441289", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Pancuronium", "source_label": "Pancuronium", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6597", "relation": "Drugshot", "target": "HP:0001636", "properties": { "id": "Tetralogy of Fallot_chemical-disease_Dichloroacetic acid", "source_label": "Dichloroacetic acid", "target_label": "Tetralogy of Fallot", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0011662", "properties": { "id": "Tricuspid atresia_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Tricuspid atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3779", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Levisoprenaline", "source_label": "Levisoprenaline", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-6061", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_LSM-6061", "source_label": "LSM-6061", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:838", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Racepinephrine", "source_label": "Racepinephrine", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:888706", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_2-[(2-Phenylethyl)thio]nicotinic acid", "source_label": "2-[(2-Phenylethyl)thio]nicotinic acid", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5320346", "relation": "Drugshot", "target": "HP:0002032", "properties": { "id": "Esophageal atresia_chemical-disease_Hydrocortisone", "source_label": "Hydrocortisone", "target_label": "Esophageal atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:14969", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Vancomycin", "source_label": "Vancomycin", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "LSM-4788", "relation": "Drugshot", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_LSM-4788", "source_label": "LSM-4788", "target_label": "Coarctation of aorta", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4197", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Milrinone", "source_label": "Milrinone", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4932", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Propafenone", "source_label": "Propafenone", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2806", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2549", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Capsazepine", "source_label": "Capsazepine", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5602", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_IN1048", "source_label": "IN1048", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:200", "relation": "Drugshot", "target": "HP:0040064", "properties": { "id": "Abnormality of limbs_chemical-disease_IN1541", "source_label": "IN1541", "target_label": "Abnormality of limbs", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2244", "relation": "Drugshot", "target": "HP:0005160", "properties": { "id": "Total anomalous pulmonary venous return_chemical-disease_Aspirin", "source_label": "Aspirin", "target_label": "Total anomalous pulmonary venous return", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3440", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Furosemide", "source_label": "Furosemide", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2771", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Citalopram", "source_label": "Citalopram", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5362032", "relation": "Drugshot", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3730", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Iohexol", "source_label": "Iohexol", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:447043", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Azithromycin", "source_label": "Azithromycin", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3054", "relation": "Drugshot", "target": "HP:0002575", "properties": { "id": "Tracheoesophageal fistula_chemical-disease_(Z,E)-Diethylstilbestrol", "source_label": "(Z,E)-Diethylstilbestrol", "target_label": "Tracheoesophageal fistula", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:37768", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Amikacin", "source_label": "Amikacin", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4197", "relation": "Drugshot", "target": "HP:0001660", "properties": { "id": "Truncus arteriosus_chemical-disease_Milrinone", "source_label": "Milrinone", "target_label": "Truncus arteriosus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4104", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Methimazole", "source_label": "Methimazole", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4713", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_PD-98059", "source_label": "PD-98059", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:104865", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Bosentan", "source_label": "Bosentan", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:3108", "relation": "Drugshot", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Dipyridamole", "source_label": "Dipyridamole", "target_label": "Double outlet right ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:126941", "relation": "Drugshot", "target": "HP:0002084", "properties": { "id": "Encephalocele_chemical-disease_Methotrexate", "source_label": "Methotrexate", "target_label": "Encephalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:6610350", "relation": "Drugshot", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_SB 203580, SULFONE", "source_label": "SB 203580, SULFONE", "target_label": "Cleft palate", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2764", "relation": "Drugshot", "target": "HP:0001669", "properties": { "id": "Transposition of the great arteries_chemical-disease_Ciprofloxacin", "source_label": "Ciprofloxacin", "target_label": "Transposition of the great arteries", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5330", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Sulfamethoxypyridazine", "source_label": "Sulfamethoxypyridazine", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:1830", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_IN1451", "source_label": "IN1451", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5320346", "relation": "Drugshot", "target": "HP:0011611", "properties": { "id": "Interrupted aortic arch_chemical-disease_Hydrocortisone", "source_label": "Hydrocortisone", "target_label": "Interrupted aortic arch", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:73707467", "relation": "Drugshot", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_BRD-K28026280-001-01-7", "source_label": "BRD-K28026280-001-01-7", "target_label": "Trisomy 18", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:4192", "relation": "Drugshot", "target": "HP:0010882", "properties": { "id": "Pulmonary valve atresia_chemical-disease_Midazolam", "source_label": "Midazolam", "target_label": "Pulmonary valve atresia", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2474", "relation": "Drugshot", "target": "HP:0001762", "properties": { "id": "Talipes equinovarus_chemical-disease_Bupivacaine", "source_label": "Bupivacaine", "target_label": "Talipes equinovarus", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:2803", "relation": "Drugshot", "target": "HP:0001539", "properties": { "id": "Omphalocele_chemical-disease_Clonidine", "source_label": "Clonidine", "target_label": "Omphalocele", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:16218975", "relation": "Drugshot", "target": "HP:0001750", "properties": { "id": "Single ventricle_chemical-disease_ZINC150345845", "source_label": "ZINC150345845", "target_label": "Single ventricle", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:40461270", "relation": "Drugshot", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_SCHEMBL18825", "source_label": "SCHEMBL18825", "target_label": "Trisomy 13", "directed": true, "resource": "Drugshot" } }, { "type": "Relation", "source": "CID:5284549", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Dorzolamide", "source_label": "Dorzolamide", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2955", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Dapsone", "source_label": "Dapsone", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6713924", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_SPBIO_002239", "source_label": "SPBIO_002239", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2662", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Celecoxib", "source_label": "Celecoxib", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:444", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Bupropion", "source_label": "Bupropion", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:1071", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_9-Cis retinol", "source_label": "9-Cis retinol", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:12035", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Acetylcysteine", "source_label": "Acetylcysteine", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6196", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Oxacillin", "source_label": "Oxacillin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707414", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_BRD-K60460488-066-01-0", "source_label": "BRD-K60460488-066-01-0", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5920", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Liothyronine", "source_label": "Liothyronine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3162", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Doxylamine", "source_label": "Doxylamine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4539", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Norfloxacin", "source_label": "Norfloxacin", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5538", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Vitinoin", "source_label": "Vitinoin", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:146570", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Escitalopram", "source_label": "Escitalopram", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-6062", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_LSM-6062", "source_label": "LSM-6062", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6077", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Acepromazine", "source_label": "Acepromazine", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:60951", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_AC1L1U7X", "source_label": "AC1L1U7X", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5095", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Ropinirole", "source_label": "Ropinirole", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2344", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Benztropine", "source_label": "Benztropine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2519", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4184", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Mianserin", "source_label": "Mianserin", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5358", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Sumatriptan", "source_label": "Sumatriptan", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-6062", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_LSM-6062", "source_label": "LSM-6062", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:31729", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Ritodrine", "source_label": "Ritodrine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5538", "relation": "DrugEnrichr", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Vitinoin", "source_label": "Vitinoin", "target_label": "Double outlet right ventricle", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5311128", "relation": "DrugEnrichr", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Goserelin", "source_label": "Goserelin", "target_label": "Trisomy 13", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:1549000", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Levocetirizine", "source_label": "Levocetirizine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4917", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Prochlorperazine", "source_label": "Prochlorperazine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:657309", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Ipratropium", "source_label": "Ipratropium", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:119607", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Valdecoxib", "source_label": "Valdecoxib", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3344", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Fenspiride", "source_label": "Fenspiride", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4679", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Pantoprazole", "source_label": "Pantoprazole", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5152", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Salmeterol", "source_label": "Salmeterol", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5021", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_LSM-5021", "source_label": "LSM-5021", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-4787", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_LSM-4787", "source_label": "LSM-4787", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5095", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Ropinirole", "source_label": "Ropinirole", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4463", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Nevirapine", "source_label": "Nevirapine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:60648", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Tiagabine", "source_label": "Tiagabine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2174", "relation": "DrugEnrichr", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Double outlet right ventricle", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2174", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Ampi", "source_label": "Ampi", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2771", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Citalopram", "source_label": "Citalopram", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:18283", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Stavudine", "source_label": "Stavudine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4601", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Orphenadrine", "source_label": "Orphenadrine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:454468", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_QC-ASN-PHE-PSI [CH(OH)CH2N]DIQ-NH-TBU", "source_label": "QC-ASN-PHE-PSI [CH(OH)CH2N]DIQ-NH-TBU", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2806", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Clopidogrelum [Latin]", "source_label": "Clopidogrelum [Latin]", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:441383", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Terconazole", "source_label": "Terconazole", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4830", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Pipamperone", "source_label": "Pipamperone", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:447043", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Azithromycin", "source_label": "Azithromycin", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:9819467", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_N-Methylparoxetine", "source_label": "N-Methylparoxetine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3869", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Dilevalol", "source_label": "Dilevalol", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:91270", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Moexipril", "source_label": "Moexipril", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5320716", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Progesterone", "source_label": "Progesterone", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4463", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Nevirapine", "source_label": "Nevirapine", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3074", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_179324-69-7", "source_label": "179324-69-7", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5759", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_LSM-5759", "source_label": "LSM-5759", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5759", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_LSM-5759", "source_label": "LSM-5759", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707547", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_BRD-K66198023-237-01-9", "source_label": "BRD-K66198023-237-01-9", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:667528", "relation": "DrugEnrichr", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_SDX-101", "source_label": "SDX-101", "target_label": "Trisomy 13", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5978", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_LSM-5978", "source_label": "LSM-5978", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4030", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Mebendazole", "source_label": "Mebendazole", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2800", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Clomifene", "source_label": "Clomifene", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5725", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_LSM-5725", "source_label": "LSM-5725", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:1130", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Thiamine", "source_label": "Thiamine", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3827", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Ketotifen", "source_label": "Ketotifen", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:54841", "relation": "DrugEnrichr", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Atomoxetine", "source_label": "Atomoxetine", "target_label": "Anencephaly", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3902", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Letrozole", "source_label": "Letrozole", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5320716", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Progesterone", "source_label": "Progesterone", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:33036", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Dexchlorpheniramine", "source_label": "Dexchlorpheniramine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:1071", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_9-Cis retinol", "source_label": "9-Cis retinol", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5320716", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Progesterone", "source_label": "Progesterone", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4756", "relation": "DrugEnrichr", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Phenazopyridine", "source_label": "Phenazopyridine", "target_label": "Double outlet right ventricle", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:54841", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Atomoxetine", "source_label": "Atomoxetine", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-6053", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_LSM-6053", "source_label": "LSM-6053", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3652", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Hydroxychloroquine", "source_label": "Hydroxychloroquine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5358", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Sumatriptan", "source_label": "Sumatriptan", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2481", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Butalbital", "source_label": "Butalbital", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:39912", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Dexibuprofen", "source_label": "Dexibuprofen", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:92727", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Lopinavir", "source_label": "Lopinavir", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5320716", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Progesterone", "source_label": "Progesterone", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3957", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Loratadine", "source_label": "Loratadine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707414", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_BRD-K60460488-066-01-0", "source_label": "BRD-K60460488-066-01-0", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:119607", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Valdecoxib", "source_label": "Valdecoxib", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:60795", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Aripiprazole", "source_label": "Aripiprazole", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:7028", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Pseudoephedrine", "source_label": "Pseudoephedrine", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2955", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Dapsone", "source_label": "Dapsone", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4091", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Metformin", "source_label": "Metformin", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5215", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Sulfadiazine", "source_label": "Sulfadiazine", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2435", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Brimonidine", "source_label": "Brimonidine", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:41317", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_9-Cis acitretin", "source_label": "9-Cis acitretin", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5362032", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Bonuten", "source_label": "Bonuten", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5538", "relation": "DrugEnrichr", "target": "Orphanet:3378", "properties": { "id": "Trisomy 13_chemical-disease_Vitinoin", "source_label": "Vitinoin", "target_label": "Trisomy 13", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:8975", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_2-Fluoroadenosine", "source_label": "2-Fluoroadenosine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:887", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Erythromycin Ethyl Succinate", "source_label": "Erythromycin Ethyl Succinate", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:1935", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Tacrine", "source_label": "Tacrine", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:456201", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Ketoconazole", "source_label": "Ketoconazole", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2512", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_NCGC00167821-01", "source_label": "NCGC00167821-01", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:38853", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Methyldopa", "source_label": "Methyldopa", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5358", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Sumatriptan", "source_label": "Sumatriptan", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2554", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2720", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Chlorothiazide", "source_label": "Chlorothiazide", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3385", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Fluorouracil", "source_label": "Fluorouracil", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707414", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_BRD-K60460488-066-01-0", "source_label": "BRD-K60460488-066-01-0", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:57369718", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_BRD-K61341215-004-01-2", "source_label": "BRD-K61341215-004-01-2", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5175", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_LSM-5175", "source_label": "LSM-5175", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6726", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Cyclizine", "source_label": "Cyclizine", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2554", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Carbamazepine", "source_label": "Carbamazepine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:35370", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Zidovudine", "source_label": "Zidovudine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:444", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Bupropion", "source_label": "Bupropion", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2083", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Albuterol", "source_label": "Albuterol", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3878", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Lamotrigine", "source_label": "Lamotrigine", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707414", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_BRD-K60460488-066-01-0", "source_label": "BRD-K60460488-066-01-0", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:185097", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Mercaptopurine", "source_label": "Mercaptopurine", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2720", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Chlorothiazide", "source_label": "Chlorothiazide", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:667466", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Chlorprothixene", "source_label": "Chlorprothixene", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2153", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Theophylline", "source_label": "Theophylline", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:64139", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Efavirenz", "source_label": "Efavirenz", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6279", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Medroxyprogesterone Acetate", "source_label": "Medroxyprogesterone Acetate", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:35370", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Zidovudine", "source_label": "Zidovudine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:41317", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_9-Cis acitretin", "source_label": "9-Cis acitretin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707414", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_BRD-K60460488-066-01-0", "source_label": "BRD-K60460488-066-01-0", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4189", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Miconazole", "source_label": "Miconazole", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4543", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Nortriptyline", "source_label": "Nortriptyline", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-6062", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_LSM-6062", "source_label": "LSM-6062", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2481", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Butalbital", "source_label": "Butalbital", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:64139", "relation": "DrugEnrichr", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Efavirenz", "source_label": "Efavirenz", "target_label": "Anencephaly", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2519", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Caffeine", "source_label": "Caffeine", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:1986", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Acetazolamide", "source_label": "Acetazolamide", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2801", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Clomipramine", "source_label": "Clomipramine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:(S, R)-Mefloquine", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_(S, R)-Mefloquine", "source_label": "(S, R)-Mefloquine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6279", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Medroxyprogesterone Acetate", "source_label": "Medroxyprogesterone Acetate", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4539", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Norfloxacin", "source_label": "Norfloxacin", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:119570", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Pramipexole", "source_label": "Pramipexole", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2678", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Cetirizine", "source_label": "Cetirizine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:64139", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Efavirenz", "source_label": "Efavirenz", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:64139", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Efavirenz", "source_label": "Efavirenz", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5920", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Liothyronine", "source_label": "Liothyronine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5203", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_79836-45-6", "source_label": "79836-45-6", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5538", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Vitinoin", "source_label": "Vitinoin", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:65999", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Telmisartan", "source_label": "Telmisartan", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73265347", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_CHEMBL3348877", "source_label": "CHEMBL3348877", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:454468", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_QC-ASN-PHE-PSI [CH(OH)CH2N]DIQ-NH-TBU", "source_label": "QC-ASN-PHE-PSI [CH(OH)CH2N]DIQ-NH-TBU", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5546", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Triamterene", "source_label": "Triamterene", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:9819467", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_N-Methylparoxetine", "source_label": "N-Methylparoxetine", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-6062", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_LSM-6062", "source_label": "LSM-6062", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4449", "relation": "DrugEnrichr", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Nefazodone", "source_label": "Nefazodone", "target_label": "Double outlet right ventricle", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:15459", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Metaxalone", "source_label": "Metaxalone", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:6710657", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_SPECTRUM_001020", "source_label": "SPECTRUM_001020", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-5083", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_LSM-5083", "source_label": "LSM-5083", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5362440", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Indinavir", "source_label": "Indinavir", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:92727", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Lopinavir", "source_label": "Lopinavir", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2366", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Betahistine", "source_label": "Betahistine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "LSM-6062", "relation": "DrugEnrichr", "target": "HP:0001719", "properties": { "id": "Double outlet right 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"resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2344", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Benztropine", "source_label": "Benztropine", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:454468", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_QC-ASN-PHE-PSI [CH(OH)CH2N]DIQ-NH-TBU", "source_label": "QC-ASN-PHE-PSI [CH(OH)CH2N]DIQ-NH-TBU", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5090", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Rofecoxib", "source_label": "Rofecoxib", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:65999", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Telmisartan", "source_label": "Telmisartan", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707466", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_BRD-K40476324-001-01-6", "source_label": "BRD-K40476324-001-01-6", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:197895", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_LSM-6025", "source_label": "LSM-6025", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5078", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Rizatriptan", "source_label": "Rizatriptan", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3331", "relation": "DrugEnrichr", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Felbamate", "source_label": "Felbamate", "target_label": "Anencephaly", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:456201", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Ketoconazole", "source_label": "Ketoconazole", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:628698", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_(3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) acetate", "source_label": "(3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) acetate", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2800", "relation": "DrugEnrichr", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Clomifene", "source_label": "Clomifene", "target_label": "Anencephaly", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4737", "relation": "DrugEnrichr", "target": "HP:0006695", "properties": { "id": "Atrioventricular canal defect_chemical-disease_Pentobarbital", "source_label": "Pentobarbital", "target_label": "Atrioventricular canal defect", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:ZINC03977765", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_ZINC03977765", "source_label": "ZINC03977765", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5282593", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_Homatropine", "source_label": "Homatropine", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2800", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Clomifene", "source_label": "Clomifene", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:73707414", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_BRD-K60460488-066-01-0", "source_label": "BRD-K60460488-066-01-0", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3878", "relation": "DrugEnrichr", "target": "HP:0002323", "properties": { "id": "Anencephaly_chemical-disease_Lamotrigine", "source_label": "Lamotrigine", "target_label": "Anencephaly", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:441383", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Terconazole", "source_label": "Terconazole", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4909", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Primidone", "source_label": "Primidone", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:447043", "relation": "DrugEnrichr", "target": "HP:0004383", "properties": { "id": "Hypoplastic left heart_chemical-disease_Azithromycin", "source_label": "Azithromycin", "target_label": "Hypoplastic left heart", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5320716", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Progesterone", "source_label": "Progesterone", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3878", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Lamotrigine", "source_label": "Lamotrigine", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:65981", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Repaglinide", "source_label": "Repaglinide", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2662", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Celecoxib", "source_label": "Celecoxib", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3152", "relation": "DrugEnrichr", "target": "HP:0000776", "properties": { "id": "Congenital diaphragmatic hernia_chemical-disease_Donepezil", "source_label": "Donepezil", "target_label": "Congenital diaphragmatic hernia", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:2477", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Buspirone", "source_label": "Buspirone", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4409", "relation": "DrugEnrichr", "target": "HP:0002414", "properties": { "id": "Spina bifida_chemical-disease_Nabumetone", "source_label": "Nabumetone", "target_label": "Spina bifida", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:464205", "relation": "DrugEnrichr", "target": "Orphanet:3380", "properties": { "id": "Trisomy 18_chemical-disease_Tenofovir", "source_label": "Tenofovir", "target_label": "Trisomy 18", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3343", "relation": "DrugEnrichr", "target": "HP:0001680", "properties": { "id": "Coarctation of aorta_chemical-disease_Fenoterol", "source_label": "Fenoterol", "target_label": "Coarctation of aorta", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:4543", "relation": "DrugEnrichr", "target": "HP:0001719", "properties": { "id": "Double outlet right ventricle_chemical-disease_Nortriptyline", "source_label": "Nortriptyline", "target_label": "Double outlet right ventricle", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:3639", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_Hydrochlorothiazide", "source_label": "Hydrochlorothiazide", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:41317", "relation": "DrugEnrichr", "target": "Orphanet:870", "properties": { "id": "Down syndrome_chemical-disease_9-Cis acitretin", "source_label": "9-Cis acitretin", "target_label": "Down syndrome", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5362440", "relation": "DrugEnrichr", "target": "HP:0001543", "properties": { "id": "Gastroschisis_chemical-disease_Indinavir", "source_label": "Indinavir", "target_label": "Gastroschisis", "directed": true, "resource": "DrugEnrichr" } }, { "type": "Relation", "source": "CID:5376", "relation": "DrugEnrichr", "target": "HP:0000175", "properties": { "id": "Cleft palate_chemical-disease_SPECTRUM_001028", "source_label": "SPECTRUM_001028", "target_label": "Cleft palate", "directed": true, "resource": "DrugEnrichr" } } ] }