Seymour Krelborn (Rick Moranis) is a nerdy orphan working at Mushnik's, a flower shop in urban Skid Row. He harbors a crush on fellow co-worker Audrey Fulquard (Ellen Greene), and is berated by Mr. Mushnik (Vincent Gardenia) daily. One day as Seymour is seeking a new mysterious plant, he finds a very mysterious unidentified plant which he calls Audrey II. The plant seems to have a craving for blood and soon begins to sing for his supper (the voice of Levi Stubbs). Soon enough, Seymour feeds Audrey's sadistic dentist boyfriend (Steve Martin) to the plant and later, Mushnik for witnessing the death of Audrey's ex. Will Audrey II take over the world or will Seymour and Audrey defeat it?