Chris Brander (Reynolds) has always been friends with Jamie Palamino (Smart), but now decides it is time to take his relationship to the next step. The problem is, is that Jamie still wants to be 'Just Friends'. When he runs away and moves to L.A., he becomes a attractive music manager, who everyone wants. When his jet crashes, when flying to Paris with his newest singing sensation, Samantha James (Faris), he ends up back home. To his surprise, he encounters Jamie again, and sets out to be more than 'Just Friends' this time.