Theatrical agent Al Stewart (Bud Abbott) has successfully booked his client, Dorothy McCoy (Dorothy Shay), "The Manhattan Hillbilly", at a New York nightclub. Unfortunately, he has also booked an inept escape artist, The Great Wilbert (Lou Costello), at the same location. During his performance, Wilbert cannot escape from his shackles and screams for help. Dorothy recognizes Wilbert's shrill scream as the 'McCoy clan yell'. More evidence of Wilbert's heritage, namely a photograph and concertina, are found in his dressing room, and prove that he is the long-lost grandson of 'Squeeze Box' McCoy, leader of the McCoy clan. Granny McCoy (Ida Moore) has been looking for Wilbert, as she will reveal where Squeeze Box hid his gold to 'kin folk' only. Al, Dorothy and Wilbert head to Kentucky, and Granny recounts the story of the McCoy-Winfield feud that began over sixty years ago. The McCoys choose Wilbert to represent them against Devil Dan Winfield (Glenn Strange) in a turkey shoot. Wilbert has never even seen a gun before, and his carelessness leads to a revival of the feud.