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25.08.2014

Herpes vaccine update 2014, antiviral medication for herpes simplex 1 - Plans Download

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While current treatment options for genital herpes have been successful in limiting the number of outbreaks the patient experiences over time, there is still no cure for this highly infectious sexually transmitted infection (STI). According to the Centers for Disease Control and Prevention, each year 776,000 people in the United States develop new genital herpes infections, caused by either the herpes simplex virus type 1 (HSV 1) or type 2 (HSV 2). Genital herpes can be spread from person to person through anal, vaginal, or oral sex when HSV 1 or HSV 2 escapes from soars in the groin area.
Researchers working on this genital herpes vaccine recruited 156 patients who had tested positive for HSV 2. Health care professionals urge people affected by genital herpes to abstain from sex during an outbreak of genital herpes sores.
A biotechnology company in Australia is now recruiting participants to test a herpes vaccine aimed to both prevent and cure herpes simplex 2 infections.
Coridon, a biotechnology company that started out of University of Queensland, has received approval to begin early-stage, Phase I human trials for its herpes simplex 2 (HSV-2) vaccine, which would be used as both a preventative vaccine and a therapeutic vaccine for those who already carry the virus. Herpes simplex 2, also known as genital herpes, is a viral infection that can infect skin cells of a certain area of the body, such as the mouth and genital area, resulting in periodic outbreaks.


The only treatments for herpes is Valtrex, which is a pill that is not completely covered by U.S. Genital herpes affects more than one in six Americans between the ages of 14 and 49, according to the Centers for Disease Control and Prevention (CDC). A vaccine to treat herpes simplex has been found safe to use in humans, further trials will test its effectiveness.
HE brought us the cervical cancer vaccine and now Professor Ian Frazer has had early success in trials for a new jab to treat the herpes simplex virus. A study funded by the pharmaceutical company AiCuris has produced a new drug known as pritelivir that shows promise as a future treatment option for type 2 genital herpes. Considering signs and symptoms of herpes can go unnoticed or can be mistaken for another skin condition, HSV 2 carriers can be unaware of their condition. We have seen very encouraging results from animal studies and we expect pivotal data showing that our vaccine, which incorporates our patented optimisation technology, to produce similar immune responses in the clinic," said Professor Frazer who founded Coridon in 2000 and is leading the study. Phase I trials usually use doses of drugs or vaccines that are meant to test the safe dosing range and may confer protection to those who participate in the trial.


Throughout the study each participant was asked to record instances of genital herpes signs and symptoms.
Three of the major antiviral drugs meant to keep genital herpes outbreaks at bay include acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex). People with a compromised immune system are especially at risk for developing genital herpes.
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