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08.03.2014

Herpes to cure cancer, traditional chinese herbal medicine - PDF Review

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Doctors say they have used a genetically engineered herpes virus to treat successfully patients with head and neck cancer.
Doctors have revealed that with the help of genetically engineered herpes virus they were able to successfully cure patients with head and neck cancer.
Head and neck cancer, which includes cancer of the mouth, tongue and throat, affects up to 8,000 people every year in the UK.
The herpes simplex virus, recognized as OncoVEX and owned by BioVex Inc, had been customized so it increases within cancer cells but unhealthy cells. Seventeen patients of cancer-affected lymph nodes in up to four doses were injected to the virus cancer-affected at the Royal Marsden Hospital, and they were also given radiotherapy and chemotherapy.
Simply two of 13 patients given the virus medications at a high dose reverted, the journal Clinical Cancer Research reported.
He is now planning a trial comparing the viral treatment with the standard treatment in people newly diagnosed with head and neck cancer.
Dr Alison Ross, senior science information officer at Cancer Research UK, said it would be some time before the treatment could be used in patients as it still needed to be tested directly against standard treatment.


About 650, 000 people were examined to have squamous cell cancer in the head and neck annually, and 350, 000 die every year worldwide.
A CURE for skin cancer is a step closer after “world first” patient trials were carried out by British researchers.
The therapy, called T-VEC, works by infecting and killing cancer cells while also kicking the immune system into action against tumours. RelatedMajority of cancers are just bad luck, not result of unhealthy lifestyle or genetics, study saysOn vitamin D, the so-called experts have it wrong, U.K.
The response was most pronounced in patients with less advanced cancers, underlining the potential benefit as a first-line treatment for metastatic cancers, which have spread to other parts of the body and cannot be surgically removed. T-VEC is a modified form of herpes virus which multiplies inside cancer cells and bursts them from within.
It works by getting into cancer cells, killing them from the inside, and also boosting the patient’s immune system. Kevin Harrington, who is based at the Institute of Cancer Research in London, said current treatments were effective if the cancer was picked up early but that many patients were not diagnosed until it was more advanced.


There were no safety concerns with use of the virus, the researchers said, and it is hoped the virus could one day be used to fight other types of cancer.
Kevin Harrington testifies that the oncolytic viruses can be harmless when used in combination of other cancer treatments for the cure of cancer patients. Normal cells detect and destroy T-VEC before it can cause damage, but it replicates easily in cancer cells because their infection defences are compromised by genetic errors. It is one of a new wave of virus-based drugs to show benefits in cancer trials, and is now the first to do so in a major randomized, controlled phase III trial.



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