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22.05.2014

Herpes labialis treatment with acyclovir, alternative medicine for bipolar 2 - Within Minutes

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A method according to claim 1 , which is a method of reducing the rate of relapse of herpes labialis in a patient, comprising topically administering to said patient a therapeutically effective amount of: polyethylene glycol or a composition comprising polyethylene glycol. A method according to claim 1 , which is a method of delaying relapse of herpes labialis in a patient, comprising topically administering to said patient a therapeutically effective amount of: polyethylene glycol or a composition comprising polyethylene glycol. A method according to claim 1 , which is a method of preventing relapse of herpes labialis in a patient, comprising topically administering to said patient a therapeutically effective amount of: polyethylene glycol or a composition comprising polyethylene glycol.
Use of polyethylene glycol, according to claim 35, in the manufacture of a medicament for reducing the rate of relapse of herpes labialis by topical administration. Use of polyethylene glycol, according to claim 35, in the manufacture of a medicament for delaying relapse of herpes labialis by topical administration.
Use of polyethylene glycol, according to claim 35, in the manufacture of a medicament for preventing relapse of herpes labialis by topical administration.
Both the herpes simplex viruses (HSV-1 and HSV-2) and the varicella zoster virus (VZV) belong to the same viral subfamily (alphaherpesvirinae). Herpes simplex viruses have a diameter of 140 to 180 nm, and therefore are classed among the large viruses. Initial infection with HSV-2 normally takes place during sexual intercourse and concerns the urogenital tract. Herpes Labialis Herpes labialis is a disease which is triggered by the herpes simplex virus (HSV). For slight or rare outbreaks of Herpes labialis, the application of 5% acyclovir cream is sufficient.
Consequently, there is an important need for alternative treatments for HSV infections and for diseases and disorders associated with, triggered by, or caused by, infection by herpes simplex virus (HSV), including, for example, herpes labialis.
Similarly, United States patent number 4,762,715 describes lipstick formulations comprising certain antiherpetic agents (heparin and zinc sulphate) for treatment of herpes labialis. Nowhere in this document is there any teaching or suggestion that polyethylene glycol itself is useful or effective in therapy for viral infections such as herpes labialis.
Figure 1 is a bar graph illustrating the reduction in the number of outbreaks (relapses) of herpes labialis in the patients of the study described herein. As demonstrated by the clinical study described herein, twice daily topical administration of PEG onto the lips of patients who were suffering at least 8 relapses of herpes labialis per year caused a substantial reduction in the rate of relapse. Without wishing to be bound to any particular theory, it is postulated that the hygroscopic properties of the PEG may contribute to its effectiveness.
In one embodiment, the PEG used in the present invention is a mixture of two or more PEG polymers with different molecular weight distributions.


In one embodiment, the PEG used in the present invention is a mixture of two PEG polymers with different molecular weight distributions.
In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 4,000 to about 10,000. In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 4,000 to about 9,000.
In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 6,000 to about 20,000.
In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 6,000 to about 15,000. In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 6,000 to about 12,000. In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 6,000 to about 10,000. In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 6,000 to about 9,000. The Herpes Simplex Virus – How an Outbreak Occurs and is Transmitted A cold herpes sore is caused by the herpes simplex virus HSV which will manifest itself in two Herpes Labialis Treatment Acyclovir types of viral infection .
The Herpes Simplex Virus – How an Outbreak Occurs and is Transmitted A cold herpes sore is caused by the herpes simplex virus HSV which will manifest itself in two types of viral infection .
The infection that appears on a person’s lip is the one that is commonly referred to as a cold sore and it may sometimes be confused with aphthous ulcers or those which are more commonly referred to as canker sores. For those people who do not present signs of HSV then it lies dormant in the bodies of the nerve cells and will replicate and travel along the axons towards the skin during an Herpes Labialis Treatment Acyclovir outbreak.
Once the outbreak has passed the virus lies dormant within the nerve bodies and it is very difficult to treat it. Polyethylene glycol for use according to claim 18, for reducing the rate of relapse of herpes labialis by topical administration.
Polyethylene glycol for use according to claim 18, for delaying relapse of herpes labialis by topical administration. Polyethylene glycol for use according to claim 18, for preventing relapse of herpes labialis by topical administration.
There are two types of Herpes simplex viruses which are called HSV-1 and HSV-2, both of which belong to the genus of the Simplex viruses of the family Herpes viridae. This cream is applied directly onto the cold sore 5 times daily, typically for 5 days, and a treatment period of 10 days should not be exceeded.


In one embodiment of the above, (b) is PEG with a weight average molecular weight (Mw) of about 8,000. These are Herpes Labialis Treatment Acyclovir similar in appearance but appear inside the mouth they are not caused by HSV.
Generally HSV is transmitted by direct contact of the lips where cold herpes sores are present or just before they appear.
The HSV-2 virus stays latent in the lumbosacral ganglions or in the peripheral tissue from where it causes the so called Herpes genitalis symptoms. Additionally, in recent years, there is an increase in the amount of viruses resistant to acyclovir, which can also reduce treatment efficacy. However, it is notoriously difficult to prepare a PEG sample with even a moderate value for "m" which is "monodisperse", that is, for which "m" is the same for all polymer molecules in the polymer sample. Herpes Labialis Treatment Acyclovir this is because the body will not have had a chance to produce antibodies the first time to help attack the virus. Unfortunately if you happen to be suffering from genital cold Herpes Labialis Treatment Acyclovir sores then you may well increase the chance of infection to your unborn child at the time of birth. In addition to the neurologic and internistic diagnostic procedure, there is also a possibility to detect the virus in the blood, with antibody testing. The acyclovir molecule is transformed (only in infected cells) to acyclovir-monophosphate by the viral thymidine kinase.
Some complications are therefore possible; one of them is herpetic keratoconjunctivitis or the highly lethal Herpes encephalitis (which has an untreated lethality of up to 80%).
However, there is one complication with high mortality: the infection of the neonate (Herpes neonatorum). Nowhere in this document is there any teaching or suggestion that polyethylene glycol itself is useful or effective in therapy for viral infections, such as herpes labialis.
These are similar in appearance but Herpes Labialis Treatment Acyclovir appear inside the mouth they are not caused by HSV. Afterwards, the monophosphate form of acyclovir is converted into the triphosphate form (acyclovir- triphoshate) by cellular thymidine kinase.



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Comments to “Herpes labialis treatment with acyclovir”

  1. LEDI:
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  2. ele_bele_gelmisem:
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  3. NIGAR:
    The infection are available and effective the virus from causing repeated herpes avoid.
  4. bayramova:
    System at its full capacity genital herpes affects more than one in six.