Management of hyperglycemia in type 2 diabetes 2015 ppt calendar,treatment of diabetes nhs exemption,lifestyle change in type 2 diabetes a process model hayes,symptoms insulin sensitivity 3.5 - PDF Review

The process of the development of the Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada included provisions to update individual chapters prior to the planned published revision in 2018 (1). However, the steering committee decided it was warranted to publish an interim commentary addressing the approval, in Canada, of a new class of antihyperglycemic agentsdsodium- glucose linked transporter 2 (SGLT2) inhibitorsdfor the pharmacologic management of diabetes.
SGLT2 inhibitors block glucose transport in the proximal renal tubule, which results in the urinary excretion of glucose, thereby lowering blood glucose and body weight (3,4). In the pharmacologic management of type 2 diabetes, metformin remains the first agent of choice (15). Use this tool to discover new associated keyword & suggestions for the search term Hypoglycemia Algorithm. These are some of the images that we found for within the public domain for your "Hypoglycemia Algorithm" keyword. Diabetes is often diagnosed in women during their childbearing years and can affect the health of both the mother and her unborn child.. Patient information: care during pregnancy for women with type 1 or 2 diabetes mellitus (beyond the basics). Webmd discusses what women with type 2 diabetes should know about diabetes complications,pregnancy, and more.. Objectives Discuss the main principles of therapy for type 1 diabetes including diet, exercise, blood glucose monitoring, oral hypoglycemic agents and insulin administration Discuss the management of type 2 diabetes including diet, exercise, blood glucose monitoring, oral hypoglycemic agents and insulin Review steps of insulin administration Compare the mechanisms of action of the available types of oral hypoglycemic agents.
Carbohydrate Counting What is carbohydrate counting and how is it used in the management of diabetes? If Julie’s CHO ratio is 1:10, how much rapid-acting insulin should she take with her lunch?
Lifestyle Modification What recommendations would you give Julie in regards to diet and exercise?
Exercise and Type 1 Diabetes Moderate to high levels of physical activity is associated with substantial reduction in morbidity and mortality in both men and women with type 1 and type 2 diabetes. Exercise and Type 1 Diabetes Hypoglycemia may be prevented by Increasing CHO intake Reducing meal time insulin prior to exercise Altering basal insulin for insulin pump users Performing resistance exercise immediately prior to aerobic exercise Exercise performed late in the day or in the evening can be associated with increased risk of overnight hypoglycemia. Driving Guidelines Measure BG level immediately before and at least every 4 hours (more often in cases of hypoglycemia unawareness) during long drives. TZD-Mechanism of Action Enhances insulin sensitivity in peripheral tissues and liver by activation of ppar- gamma receptors Eg. Secretagogues-Mechanism of Action Sulfonylureas bind to SU receptor inhibiting an efflux of K.
Penta Sure has been specially designed according to the guidelines of the American Diabetic Association (ADA) and the World Health Organization (WHO). The College of Pharmacy of Gulf Medical University (GMU), the leading private medical university in the region owned and operated by Thumbay Group, held a seminar titled “Safe, Effective and Affordable Use of Anti-Diabetic Medicines” at the University campus in Al Jurf, Ajman on Friday, 11th December 2015, organized by the Health Communications Division of Thumbay Group. Health Tip of the DayLive’lyTo Start: The program began with an in-depth consultation with the nutritionist including a complete body analysis.
An updated literature search that focused on new evidence published since the development of the 2013 guidelines yielded 1787 citations.


Two agents from this class have received notice of compliance by Health Canada since the publication of the 2013 guidelines: canagliflozin and dapagliflozin (2). Network meta- analyses show that, when added to metformin, SGLT2 inhibitors generally have similar or slightly better efficacy in lowering glycated hemoglobin levels than do other anti- hyperglycemic agents (5,6).
SGLT2 inhibitors are a new class of antihyperglycemic agents available for the treatment of diabetes in Canada, and their use can be considered in management plans individualized to meet patients’ characteristics, as outlined in Figure 1. Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada: Methods. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Systematic review and network meta-analysis to compare dapagliflozin to other diabetes medications in combination with metformin for adults with type 2 diabetes.
Bayesian network meta-analysis to assess relative efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin.
Efficacy and safety of canaglilozin in subjects with type 2 diabetes: Systematic review and meta-analysis. Long-term efficacy and safety of canagliflozin over 104 weeks in patients aged 55-80 years with type 2 diabetes. Euglycemic diabetic ketoacidosis: A potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes mellitus and chronic kidney disease. She was diagnosed at the age of 7 when she developed symptoms of polyuria, polydipsia and polyphagia.
Basal-Bolus Approach *Insulin effect images are theoretical representations and are not derived from clinical trial data.
Patients are encouraged to always review the pattern of their glucose levels to determine if correction factors or boluses are working appropriately.
Not all carbohydrate foods are created equal The glycemic index (GI) describes this difference by ranking carbohydrates according to their effect on our blood glucose levels. In type 1 diabetes, there is little or no endogenous insulin secretion and no physiological regulation of insulin levels. What advice should be given to people with diabetes in regards to glucose monitoring and driving? Always carry BG monitoring equipment and supplies of rapidly absorbable carbohydrate within easy reach (e.g.
The use of diabetic-specific formulas as oral supplements and tube feeds are associated with improved glycemic control and lower diabetic complications. Topics discussed included scientific efficacy and safety profiles of novel approaches to the management of hyperglycemia in type 2 diabetes, review of current oral anti-diabetic products and their future developments, current trends and future challenges of insulin drug delivery systems, clinical pharmacokinetics and drug-drug interactions of newer anti-diabetics, dose adjustments of anti-diabetic medicines in patients with renal and hepatic impairment, prevention and management of rare but serious adverse events of anti-diabetics, and the implications and guidelines for the safe use of intravenous insulin in emergency. As I was not overweight nor did I have any serious health concerns as such, I was put on the a la carte menu at  1200 kcal per day. After review of these citations, the chapter authors advised the steering and executive committees that there were no significant changes in evidence to warrant the formulation of any new recommendations or the revision of any current recommendations.


This update was deemed necessary by the steering committee because the addition of a new class of pharmacologic therapy represents a significant change in the management options for diabetes, yet the next complete update of the guidelines is still 3 years away.
The incidence of hypoglycemia with SGLT2 inhibitors is rare unless they are used in combination with insulin or sulfonylureas (3).
FDA warns that SGLT2 inhibitors for diabetes may result in a serious condition of too much acid in the blood. Type 1 diabetes: - teach how to match insulin to CHO intake - maintain regularity in timing and spacing of meals -low glycemic index foods 3.
As such, it was recommended that a full update of the chapter be deferred until the planned revision of the entire Clinical Practice Guidelines in 2018. Because of the glycosuria resulting from the use of these agents, there is an increased risk for urinary tract infections, genital mycotic infections and hypotension caused by osmotic diuresis (3). Sucrose and sucrose-containing foods can be substituted for other CHOs as part of mixed meals up to a maximum of 10% of total daily energy, provided adequate control of BG and lipids is maintained.
Although SGLT2 inhibitors lower blood pressure (3) and raise high-density lipoprotein cholesterol, they elevate low-density lipoprotein cholesterol modestly (7,8), and their cardiovascular safety remains unknown and awaits long-term clinical trials.
All about living with type 2 diabetes including information on prediabetes, symptoms, diet, recipes, diagnosis, treatment, causes, control, complications.. A number of lifestyle factors are known to be important to the development of type 2 diabetes, including obesity and being overweight (defined by a body mass index of. An imbalance in bladder cancer was noted with dapagliflozin in early clinical trials; however, many of the subjects with bladder cancer had pre-existing hematuria (9). Adults: no more than 7% of total daily energy from saturated fats and should limit intake of trans fatty acid. There have been reported cases of diabetic ketoacidosis, without the usual elevated blood glucose, in patients with type 2 diabetes being treated with SGLT2 inhibitors (10-13).
T1DM: informed of delayed hypoglycemia resulting from alcohol consumed with or after the previous evening’s meal. Patients on an SGLT2 inhibitor with symptoms of breathing difficulty, nausea, vomiting, abdominal pain, confusion or fatigue, even in the absence of high blood glucose, should be evaluated for ketoaci- dosis.
If the ketoacidosis is confirmed, appropriate measures should be undertaken to correct the acidosis.
The SGLT2 inhibitor therapy should be interrupted and its subsequent long term use should be reassessed (10,13). Figure 1 sum- marizes the therapeutic considerations for SGLT2 inhibitor therapy in the management of type 2 diabetes mellitus. The efficacy of SGLT2 inhibitors with respect to glucose lowering is dependent on their effects on urinary glucose excretion, which is attenuated in patients with renal dysfunction (14). Figure 2 summarizes the contraindications to use of SGLT2 inhibitors in patients with declining renal function based on product monographs.



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