Diabetes mellitus powerpoint presentation 2011 gratis,nature reviews drug discovery diabetes research,defects in insulin for type 2 diabetes - 2016 Feature

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All templates found in Bestpowerpointtemplates are uploaded by site users for education purpose only and the templates are linked to respective template designer''s page. Pathophysiology of Type 2 Diabetes Insulin Resistance • Insulin Resistance starts very early in the course of the disease. Pathophysiology of Type 2 Diabetes Beta cell defect • al type 2 patients have at least a relative defect in both beta-cel function and mass. Pathophysiology of Type 2 Diabetes Beta cell defect • This first-phase insulin response is absent in type 2 diabetic patients contributing to the excessive and prolonged glucose rise after a meal in those with diabetes Diabetologia. Pathophysiology of Type 2 Diabetes Other Factors • Historically, hyperglycemia in diabetes has been viewed as a failure of insulin-mediated glucose disposal into muscle and adipose tissue. Pathophysiology of Type 2 Diabetes The Glucagon Factor • In response to a carbohydrate-containing meal, individuals without diabetes not only increase insulin secretion but also simultaneously decrease pancreatic alpha-cel glucagon secretion. Pathophysiology of Type 2 Diabetes The Glucagon Factor • In contrast, the glucagon secretion in type 2 diabetics is not decreased, and may even be paradoxical y increased. Pathophysiology of Type 2 Diabetes The Gastric Emptying Factor • Many factors can affect the rate of gastric emptying. Pathophysiology of Type 2 Diabetes One last observation • In 1930 La Barre described a greater effect of oral rather parenteral glucose in increasing insulin secretion. Actions of GLP-1 • Important, as glucose levels approach the normal range, the GLP-1 effects on insulin stimulation and glucagon inhibition declined (glucose dependence – reduction of hypoglycemia. Actions of GLP-1 The Problem • Unfortunately, GLP-1 is rapidly broken down by the DPP-IV enzyme (very short half-life in plasma – requires continuous IV infusion).
The solution Two options: • Incretin mimetics are glucagon-like peptide-1 (GLP-1) agonists.
Incretin mimetics Exenatide • The first incretin-related therapy available for patients with type 2 diabetes.
Clinical Trials of Exenatide • Three pivotal randomized, double-blind, placebo- control ed, multicenter clinical trials were conducted to support the approval of exenatide (the AMIGO studies).
Nausea With Exenatide • was seen uniformly across the clinical trials, although most episodes were mild-to-moderate in intensity and generally intermittent. Incretin mimetics Recent Advances • Liraglutide: Another GLP-1 analog with longer half-life, similar to exenatide with once-daily injection. Dipeptidyl Peptidase-IV Antagonists • The concept is to al ow the endogenous GLP-1 to remain in circulation for a longer period.


Dipeptidyl Peptidase-IV Antagonists Sitagliptin and Vildagliptin • Sitagliptin and vildagliptin are the first agents in this class to have received FDA approval.
Dipeptidyl Peptidase-IV Antagonists Recent Advances • During the last ADA meeting in Chicago, Il iois, 22-26 June 2007, fifty-five presentations addressed 12 different DPP-IV inhibitors and “… more wil be seen during the coming months…” • Some members seem particularly interesting as saxagliptin (? Summary • Insulin resistance and relative insulin secretory defect are key elements of the pathogenesis of type 2 diabetes.
Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Type 2 diabetes is a condition that is diagnosed or discovered in people who are over the age of 40. When one has eaten, the food that is consumed is broken down in the gut into simple blood sugar. Type 2 diabetes is a diabetic condition that is independent of insulin or happens upon maturity.
Weight loss might come about even when one is eating the same or not controlling their diet. This site is for information and support only and NOT a substitute for professional medical advice, diagnosis, or treatment. Insulin pumps are used most often by people with type 1 diabetes due to their more complicated insulin injection regimen.
In the buff being rude People are always shocked to hear it 4) The Maintenance Phase consuming the right level of carbohydrates for ongoing weight control.
A place where intense concentration provides the ability to cultivate valuable skills such as programming a means to shape and control the world we live in. Working with your diabetes educator or physician develop a plan that includes how often to measure blood glucose and urine ketones which over-the-counter medicines to take what and how often to eat The association between obesity and diabetes has long been recognized but the molecules responsible for this association are unclear. Insulin resistance and the inability of beta cells to function appropriately develop type 2 diabetes. You can always get in touch with us through the feedback form if you have questions on editing these designs, or want more info on licensing.
If you interesting in "Incretin Based Therapy of Type 2 Diabetes Mellitus" powerpoint themes, you can download to use this powerpoint template for your own presentation template. Glucagon-like peptide-1 (GLP-1) • a 30-amino acid peptide secreted in response to the oral ingestion of nutrients by L cells, primarily in the ileum and colon. Diabetes mellitus is the clinical term to refer to and it occurs when the level of sugar or glucose in the blood goes higher than normal. The sugar in the form of glucose passes into the bloodstream ad this is taken up by the cells in order to make energy. The newly replicated cells of your body will be made of the substances found in these foods.
Combine that with the Hedge Trimmer and Blower (whose batteries you can use interchangeably) and there’s no job I wont have enough juice for.


Urine testing is also an important part of testing for ketones which are dangerous by-products of diabetes that’s out of control. For viewing only, you can play with our flash based presentation viewer instead of downloading the ppt file. If beta-cell function is normal, one can compensate for insulin resistance by increasing insulin secretion. However, type 2 diabetes patients are resistant to its action (high blood level), making it a less attractive therapeutic target.
In type 2 diabetes onea€™s system is still able to prepare insulin but there are deficiencies in its working. Control of diet is most important especially in the content of the meals and the timing of the meals. Symptoms Type 1 Diabetes Blurred Vision last month the journal Diabetes Care published a study by the Mount Sinai research group that showed how short-term intensive insulin therapy can reduce glycemic variability.
There can be several reasons for cloudy urine but diabetes does not really have a direct effect on the color or clarity of urine.
The cluster of medical conditions that make up the insulin resistance syndrome or metabolic syndrome places a person at risk of developing type 2 diabetes and atherosclerosis (hardening of the arteries).
A few months later during one particular week I kept hearing everyone talking about the most amazing thing in the BAR ( Bar Area Reporter a weekly local gay newspaper). It’s his ineffectiveness as a politician and his time in office should be measured solely on this basis.
The earplugs are good, but if you're like me you'll still feel some pain if you use them alone.
In between meals, the blood glucose level starts to fall and that is when the insulin level also begins to fall. By reducing intake of food items that are easy carbs and regulating the blood sugar levels at all times, one will be able to control their diabetic symptoms to a large extent.
In the United States xylitol is approved as a food additive for special dietary needs such as diabetes. According to the American Diabetes Association before people develop Type 2 diabetes they almost always have pre-diabetes – higher than normal blood glucose levels. Glucogen or fat then gets converted into glucose which is released into the bloodstream from the cells. In the animals receiving 5, 10 and 20% xylitol decreased food-intake and weight gain was recorded. Bronze Sculptures Bronze Statues Sculpture And Statue Art Animals Bronze sculpture bronze statue bronze statues sculpture statue Offering a standardized iq quiz measuring intelligence quotient.



Innervatie m psoas
Stubru 2016
Type 2 diabetes mellitus epidemiology
11.09.2015 Diabetes 2 Cure


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