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A "major breakthrough" in understanding how glucose uptake is stimulated in brown fat could be used to develop new medications for type 2 diabetes, according to a new study published in the Journal of Cell Biology. Insulin or oral medication is sometimes needed to control type 2 diabetes, which currently has no definitive treatment or cure. The researchers, from Stockholm University in Sweden, say they have uncovered a new mechanism that encourages glucose uptake in brown fat. By using this new knowledge, the researchers say they may be able to stimulate this signalling pathway with drugs, lowering blood sugar levels and potentially even curing type 2 diabetes. Currently, there is no definitive treatment or cure for type 2 diabetes, a disease that affects more than 382 million people worldwide.
In a person with the condition, the body's tissues are unable to respond to insulin, rendering them unable to take up sugar from the blood. Very high blood sugar levels are dangerous to organs in the body and can lead to heart disease, kidney failure, blindness, peripheral nervous system damage, amputations and even early death.
The researchers explain that brown fat is active in adults, acting as one of the bodily tissues that can be encouraged to take up large amounts of glucose from the bloodstream to use as a fuel source to create body heat. As such, increasing the uptake of glucose in brown fat can quickly decrease blood sugar levels, they say. He adds that they have shown the mechanism through which "adrenergic receptors" - found on brown fat - encourage the uptake of glucose. The next step is to investigate how stimulating the pathway could affect glucose homeostasis in rodents, creating a potentially effective treatment for both type 2 diabetes and obesity. In the US, type 2 diabetes accounts for 90-95% of diabetes cases, and it is typically linked with older age, obesity, physical inactivity, and family and personal history. Medical News Today recently reported on a new clinical trial set to investigate whether a common blood pressure drug could reverse type 1 diabetes in humans. Additionally, for American Diabetes Month, we presented a feature on spotting the signs of child diabetes. Visit our Diabetes category page for the latest news on this subject, or sign up to our newsletter to receive the latest updates on Diabetes. Please use one of the following formats to cite this article in your essay, paper or report:MLAEllis, Marie.
For any corrections of factual information, or to contact our editorial team, please see our contact page. Please note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional.
Learn all about diabetes, a lifelong metabolism disorder that causes high blood sugar levels. Learn all about type 1 and type 2 diabetes and the differences between the two conditions in our article about the diabetes mellitus metabolism disorder. One simple way to cut down your risk by 22% is to limit or, even better, eliminate sugary drinks.
A new study in the journal, Nature Medicine, has found a link between a high fat diet and Type 2 diabetes. Although the link between obesity (often caused by eating a high-fat diet) and Type 2 diabetes (also known as diabetes 2 or sugar diabetes in South Africa) has been known for some time, this new study shows how fat disrupts the production of the enzyme GnT-4a which allows the cells in the body to absorb glucose.
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The content of this site is intended as information and is not a substitute for seeking advice from a medical professional. Gout is a type of arthritis that can affect different body parts like the ears, small joints on the hands, wrists, ankles or knees. The exact cause is unknown, but a high amount of uric acid in the body is one of the reasons. Gout is linked to other types of health problems, such as hypertension, diabetes, and uric acid kidney stones, so it is important to get proper medical treatment. Apple cider vinegar, which is used to treat headaches and acid stomach, also helps treat gout and arthritis. If you find this remedy helpful, you can increase the dosage of apple cider vinegar to up to two tablespoons. The anti-inflammatory properties present in ginger root can be very helpful in relieving pain and inflammation.
Mix equal amounts of fenugreek powder, turmeric powder and dried ginger root powder (sonth).
You can simply add ginger root in cooking recipes, or eat a small, raw piece of ginger root daily. You can also add one-half teaspoon of ginger root to one cup of boiling water and mix it well. Another option is to make a paste of ginger root with a little water and apply this paste on the affected area.
To get relief from gout pain, it is essential to alkalize the body and neutralize the excess uric acid in blood stream.
Another option is to add the juice of half a lemon to a glass of water and drink it three times a day.
Cherries, whether sweet or sour, can also be very helpful in treating gout due to their antioxidant properties.
Epsom salt is another useful ingredient for home treatment of gout and other forms of arthritis.
Simply eat one or two bananas daily, and soon you will notice improvement in your condition.
It is very common to hear people say, “An apple a day keeps the doctor away.” It’s a good, healthy habit to eat at least one apple daily, especially when you have gout. Activated charcoal is known to absorb uric acid; hence, it can be safely used for gout treatment. Alternatively, you can take activated charcoal capsules orally to relieve gout pain and inflammation. You can use an ice pack for about 15 minutes, but wrap it in a towel before placing it on the affected area. So, if you are suffering from gout, simply try these natural remedies to get relief from the pain and inflammation. Because insulin is released after eating to regulate blood sugar, when the insulin signal no longer functions properly, blood sugar levels rise. Tore Bengtsson of Stockholm University's Department of Molecular Biosciences - discovered a new signal pathway that differs from the one triggered by insulin. Type 2 diabetes can be prevented by making healthy food choices, exercising and losing weight. Diabetes type 1 is a disease in which a person is born with a body that simply does not produce insulin. These are people who are fighting to find a cure for diabetes or want to spread awareness of the disease.

Studies show that even one sugary drink a day can increase your chances of getting diabetes. Extremely obese people will have a 70% less chance of getting diabetes if they lose just 5% of their weight. First, increasing your whole grain intake can  help you lower your chances of getting diabetes.
Look on the ingredient list for sugars with these names: brown sugar, corn sweetener, corn syrup, dextrose, fructose, high fructose corn syrup, invert sugar, maltose, malt syrup, molasses, sugar, and sucrose. In fact, there are many benefits to it… Check out our blog posts on a healthy diet for people with diabetes, then go and eat some fresh vegetables! Symptoms frequently include acute pain, swelling, intense tenderness and inflammation in the joints. Some other possible causes are genetics, excessive consumption of alcohol, lack of physical exercise, excessive protein intake and too much stress.
In addition, some easy-to-follow home treatments can promote healing and provide symptom relief. Cherries also contain anthocyanins, which can reduce inflammation as well as minimize gout flare-ups. The high amount of magnesium present in Epsom salt will also improve the condition of your heart and lower high blood pressure.
The high potassium content in bananas will help convert uric acid crystals into liquid form that will be flushed out of the body later through urination.
The malic acid present in apples will help neutralize uric acid in the body and thereby relieve gout pain and inflammation.
WHEN YOU HAVE GOUT, DO NOT USE ICE DIRECTLY ON THE SKIN; IT CAN DAMAGE THE SKIN AND MAKE YOUR CONDITION WORSE. Though it can be controlled with these same activities, insulin or oral medication is often necessary. Diabetes type 2 is a disease in which a persons body stops absorbing insulin or there is not enough of it. Sugar and unhealthy body weights are the number one reason diabetes is a problem in our society. Even if you are not obese but slightly overweight, maintaining a healthy weight will decrease your chances enormously. Along with lemon juice, also eat other fruits rich in vitamin C to strengthen the body tissues.
Soaking the affected body part in warm water mixed with Epsom salt relaxes aching muscles and relieves pain. Bananas also contain moderate amounts of vitamin C, which can be very effective in managing swelling and pain.
When yo do eat out, look at the nutritional fact menus that many sit-down and fast food restaurants have and eat as healthy as possible. Both website are dedicated to educating and informing people with articles on powerful and concealed information from around the world.
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According to the American Diabetes Association, “Diabetes causes more deaths a year than breast cancer and AIDS combined.

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