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The global generic drug market should grow at a compound annual growth rate of 15% over five years to be worth just under $169 billion in 2014, according to a report from BCC Research.
The generic drug industry (as a part of the pharmaceutical business) covers the marketing and sale of medication containing the same active ingredients and dosages as brand-name drugs manufactured by the pharmaceutical industry. Generic drugs are under the same governance as brand-name drugs and must adhere to the same standards.
Drugs coming off patent through 2014 represent a forecast annual loss of $136 billion, according to industry analysis.
Generic drugs took all of the top-10 spots for the most-prescribed drugs in the US last year, as ranked by the IMS Institute for Healthcare Informatics.
Possibly further boosting future sales is the looming patent expiration of several of the pharmaceutical world’s star prescription brand-name drugs, for which generics are poised to claim sizeable market share. In March 2012, depression drug Lexapro will come off patent, leaving room for generic Escitalopram. BCC Research shows Teva Pharmaceutical Industries to hold just under 20% of the global generic drugs market, followed by Sandoz, with 10% of the market.
The generic drug market is gaining increasing ground over brand-name pharmaceuticals, with the FDA reporting that generics account for more than 70% of prescription drugs in the US. The 'Global and Chinese Imatinib Industry, 2011-2021 Market Research Report' is a professional and in-depth study on the current state of the global Imatinib industry with a focus on the Chinese market. ReportLinker simplifies how Analysts and Decision Makers get industry data for their business. This is Steven Salzberg's blog on genomics, pseudoscience, medical breakthroughs, higher education, and other topics, including skepticism about unscientific medical practices.
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We are suppliers, providers and exporters of many charts and models including Endocrine System Charts . I saw you mentioned on this YouTube video and thought you might like to note the criticism, in case someone less friendly hits you with it before you find out about it.
But the real cracker is when Pee Pee claims I have a “professional” vested interest in defending saturated fat and cholesterol.
Pee Pee hasn’t stopped to consider that maybe I do genuinely believe the cholesterol theory of heart disease is an unscientific load of garbage. If Pee Pee had enough brain power to examine the evidence in its entirety, maybe he’d come to the same conclusion too.
Heaven forbid Pee Pee pull his head out of his ass and examine the evidence in its entirety.
Sorry for the interruption folks, that was my wealthy supermodel girlfriend…looks like I have to cancel golf with Bill Gates this weekend, I’ll be hobnobbing instead with the elite on the French Riviera…gee, this life of opulent and absurdly lavish wealth I allegedly live can be so inconvenient sometimes. One day, I hope to meet at least one of these idiots who accuse me of being in it for the money, so I can take the opportunity to shove both of my books firmly up their keester. But whatever the hell you do, don’t stick your neck out and call bullshit on the scams and dogmas that pervade our easily-led, instant gratification-seeking society. Seriously, if I could go back in time to the moment where I got the bright idea to write a book, I’d slap myself across the face, ask myself what the hell I was thinking, and go apply for a second job at McDonalds. Here’s what you need to do instead: Become an outlaw biker or join a street gang or underworld faction in your local city.
If knives, guns and prison terms are a little too hardcore for your sensibilities, or years of an emaciating vegan diet have made you patently unsuitable for such a lifestyle, then there’s a less violent way, but it does involve becoming a fat little porker. Above (top): Cholesterol drugs ("lipid regulators") are the number one selling class of drugs in the US.
What about the so-called ‘non-profit’ organizations like the American Heart Association that make hundreds of millions of dollars each year promoting the cholesterol sham? But that’s OK Pee Pee, you ignore the blatant commercial nature of the AHA’s endorsement scheme.And you ignorethe billions of dollars that have been made by the pathology industry as a result of performing useless cholesterol tests. That’s right, you ignore them, because all the above-mentioned have no vested professional interest in pushing their agendas at all, no sirree. Pee Pee, if you are such a devoted defender of the truth and such a fierce exposer of people who publish bullshit for monetary reward, why don’t you attack T.
Note the minimal time and space I devote to the study: A grand total of 2 short paragraphs. Believe me folks, I've written a hell of a lot more than 2 paragraphs when it comes to the lipid hypothesis.
If you believe something that not many other people believe, in PP’s worldview, you must be a “fringe” lunatic.
You know, there was once a time when almost everyone in the world believed the Earth was flat. Whether the Holmberg paper has been cited by 1000, 25, or zero other researchers is utterly irrelevant.
The paper found that daily fruit and vegetable consumption was associated with a lower risk of heart disease, but only when accompanied by high fat dairy consumption. It was Ancel Keys’ shamelessly biased Six and Seven Countries studies – epidemiological studies – that really got the anti-saturate, anti-cholesterol ball rolling(15,16).
But despite his disdain for epidemiological data, Pee Pee is happy to wank on about it when he thinks that doing so supports his case. Pee Pee claims the participants of the Holmberg study were not “a very healthy bunch” and asks if you think it’s a good idea to base your lipid-lowering decisions on this single study. In The Great Cholesterol Con – which, being my definitive and all-encompassing book on the topic of cholesterol and CHD, Pee Pee should have mentioned but didn’t, instead preferring to focus on a single blog post – I present the data for over two dozen prospective studies examining the relationship between saturated fat intake and CHD mortality. Researchers from Harvard University and the Children’s Hospital Oakland Research Institute pooled the data from twenty-one prospective epidemiologic studies examining the association of dietary saturated fat with coronary heart disease (CHD), stroke, and cardiovascular disease (CVD; CHD inclusive of stroke) risk. An almost identical relationship with cardiovascular disease (ie, CHD, heart failure, stroke) was observed. When coronary heart disease mortality was examined in isolation, the association with cholesterol appeared to follow a U-shaped curve.
Again, what is the sneering Pee Pee’s comment on this uncomfortable contradiction to his garbage beliefs?
But I guess Pee Pee just ‘forgot’ to mention that in his whiny little YouTube video…or maybe Pee Pee has misogynistic tendencies and doesn’t think women matter. Pee Pee also wanks on about LDL levels…well, also freely available on my website since its inception is my peer reviewed paper “LDL: Bad Cholesterol, or Bad Science?” which Pee Pee could also have mentioned, but didn’t.
It’s now time to turn the accusatory spotlight back on Pee Pee, and see how his idiotic claims are a threat to human health. In Chapter 8 of The Great Cholesterol Con, I tabulate and discuss the results of the eighteen clinical trials conducted since 1955 that compared the effect of saturated fat reduced diets with diets higher in saturated fats.
It must also be pointed out that saturated fat restriction failed miserably to reduce CHD mortality even though it significantly reduced serum cholesterol levels in almost all of the intervention groups. It must again be emphasized that the dietary intervention studies discussed in this chapter represent sixty years' worth of intensive research, the expenditure of hundreds of millions of dollars in public funds, and an enormous amount of time and effort. Among the participants of the giant Women’s Health Initiative trial who had pre-existing cardiovascular disease, the relative risk of non-fatal and fatal CHD was increased by twenty-six percent among those following the reduced fat diet. In other words, controlled clinical trials show that following low-fat and low-saturate diets will either make no difference to your CHD and overall mortality risk, and in some instances may actually increase it. In research involving fish oil, CHD mortality was significantly reduced even though LDL levels went up.
Autopsy studies have shown a complete disconnect between cholesterol levels and extent of atherosclerosis. Pee Pee pooh-poohs the relationship between low cholesterol and increased mortality, rather ironic from someone who accuses others of “playing with your heart”. As I explain right at the start of TGCC – you know, the book that has allowed me to become the carefree billionaire playboy I am today, who uses hundred dollar bills to snort pharmaceutical-grade resveratrol then throw them out of my limousine window when I’m done – 95% of CHD deaths occur in those over 55, which means that only a small percentage of CHD deaths can claim to have even a statistical relationship with blood cholesterol.
If you are over fifty, and starting to become a little pissed by the idea that for years you’ve listened to people like Pee Pee and abstained from many of your favourite foods for no good reason, then wait – there’s more! Thus, the data from the Framingham Study, the longest-running project examining the connection between cholesterol and CHD, has shown that declining cholesterol does not increase longevity, but instead increases one's risk of death from all causes, including cardiovascular disease[18]. Pee Pee dismisses outright the contention that low cholesterol could ever possibly cause a decline in mental function. Numerous studies have shown that low cholesterol is associated with poorer cognitive function – as well as increased suicide, homicide and risk of death from other violent causes that may reflect an increased tendency towards aggression and impulsive behaviour. Contrary to what Pee Pee would have you believe, several such studies have already been conducted.
In one of these, healthy subjects were randomized to receive either a low-fat or standard diet for twelve weeks. A 1992 double-blind, placebo-controlled trial found that healthy young men randomized to receive the popular cholesterol-lowering drug lovastatin (Mevacor) displayed significant deterioration in divided attention (the ability to simultaneously focus on multiple tasks and stimuli), vigilance (the ability to sustain attention) and global performance (a more general assessment of cognitive function). In 2000, Muldoon and his colleagues reported the results of a double-blind, placebo-controlled trial that assessed cognitive function and psychological well-being in healthy adults randomly assigned to receive either lovastatin or a placebo. The ability of cholesterol-lowering treatments to impair reaction time and mental focus goes a long way towards explaining the well-documented increase in accident risk among individuals with low cholesterol levels(21). At the beginning and end of each diet period, every subject underwent a battery of psychological assessments, including various mood state questionnaires and an interview by a psychiatrist who was blinded to the participant's dietary status. What the researchers found was that, while ratings of anger-hostility slightly declined during the high-fat diet period, they significantly increased during the low-fat, high-carbohydrate diet period.
When adult male monkeys were fed a 'luxury' diet (43% calories from fat) or a 'prudent' diet (30% calories from fat, and 85% less cholesterol than the luxury diet), researchers observed that the low-fat diet monkeys were more irritable and initiated more aggression than the luxury diet animals.
These results are also consistent with studies that have shown a significant increase in the frequency and severity of depression amongst middle-aged and elderly men with low cholesterol levels when compared to those with higher levels(25,26). The problem with the reigning cholesterol dogma is that it has pretty much overtaken the entire coronary arena of modern medicine. Mrs Calabio should never have been on statin drugs in the first place – they have never been shown to extend the life of females by a single day.
As a result of his brother's premature heart problems, it had been suggested to Barker that he visit his doctor for a precautionary examination. What followed over the ensuing years was dialysis, continual muscle and joint pain, fatigue, nausea, traumatic nightmares,  frequent and urgent urination, a raised PSA level, neuropathy, even an operation for the hiatus hernia caused by his continual vomiting. Because his doctor was so brainwashed by the bullshit cholesterol theory he had no qualms whatsoever about prescribing a healthy, CHD-free man a toxic drug he simply did not need.
But again, when I do what I earnestly believe to be the right thing and point this out to the world, assholes like Pee Pee accuse me of being a fringe lunatic who only writes what I do because I have some professional vested interest in doing so.
Whether it’s a Jimmy Moore or Angry Dick-type dimwit ridiculing me for calling BS on the fallacious low-carb metabolic advantage dogma that’s keeping them fabulously fat, or a screwball vegan angry at me for calling BS on the idiots who’ve suckered them into abandoning nature’s most nutrient-dense food, there are a lot of folks out there who really hate people who lay out the plain facts. Drugs can be prescribed under their chemical name without specifying a particular pharmaceutical brand or company.
Generics help reduce government spending on healthcare, accounting in part for a near 5% decrease in US drug spending, reports the FDA. Only three brand-name drugs ranked in the top 25, highlighting the strong foothold secured by generics.


Top generic drugs to enter the market this year are expected to be Methylphenidate (an attention deficit hyperactivity disorder drug taking over from Concerta) and Levofloxacin (a copy of antibiotic Levaquin). In the same month generic Quetiapine will be poised to compete with antipsychotic Seroquel. The US market for generic drugs is forecast to show more than 10% CAGR, reaching $54 billion in 2014. Here's where I can say what I really think about abuses and distortions of science, wherever I see them.
PP, who I shall refer to from this point on as Pee Pee, to more accurately reflect his malevolent piss-ant status, calls me a “cholesterol confusionist”, a “saturated fat apologist” with “fringe views” and in a mocking tone of voice calls me “cutting edge”, the inference being that I’m so far out on the lunatic fringe even the Flat Earth crowd thinks I’m a little strange.
There was once a time, years ago, when I too was a brainwashed moron like Pee Pee and believed the cholesterol theory. But he’s a myopic vegan wanker who, like most dogmatic twats, is only capable of honing in on the research that seems to support his views.
He cuts away the evidence that doesn’t support his views, then pushes it right over the edge of his desk into the wastepaper basket.
That would mean having to abandon his closely-held beliefs, something that no self-respecting dogmatist would ever do. Maybe the newly transplanted books will bring them all the prestige and lavish wealth I’ve yet to receive. They want their feeble little minds to be entertained and distracted from the things that really matter. Counting up all the hours of research, writing, fact-checking, editing, and all the bullshit involved with self-publishing, I’m pretty certain I would have come out ahead financially if I chose to flip burgers instead.
Get a bunch of tattoos, get high on drugs and shoot a bunch of people, then after a few years of being a total curse on society, go ahead and write your “memoirs”. Yep, become sedentary and eat a bunch of high-calorie crap, gain weight until you need to wear a girdle to hold your bulbous gut in, then write a fat loss book that resolves around some scientifically invalid, hare-brained gimmick. If you don’t believe me, write to Uffe Ravnskov, perhaps the best known cholesterol debunker, and ask him how much money he’s made “apologizing” for saturated fat and cholesterol. Oh mighty Pee Pee, may I ask you this: If the pittance I’ve earned from writing about the cholesterol sham qualifies me as a charlatan with a vested professional interest, what about the drug companies that make billions each year from cholesterol-lowering drugs?
Are you okay with the fact that over the years companies who produce sugar-laden shit have been able to buy the AHA’s approval?
You see, it’s me, Anthony Colpo, with my self-published modest-selling book The Great Cholesterol Con, that is the true exploiter of the cholesterol theory of heart disease. Colin Campbell, whose best-selling book The China Study has repeatedly and clearly been shown to contain one mistruth after another?
Never mind that the countries involved in his studies were handpicked to support his idiotic agenda. Let me answer for you: No, it’s not a good idea to ever base your health decisions off a single study, when you have dozens of others to also consider. Hot on the heels of that report comes a similar paper, appearing in the American Journal of Clinical Nutrition, also concluding that saturated fat shows no association with heart disease or stroke. Meaning that, as cholesterol went up, the risk of visiting that big Zara outlet in the sky went down. No matter what the cause of death, if you’re the last one left standing, then you achieved the best result.
Because study after study shows that cholesterol has little to no relationship to heart disease in women (the real reason for the extremely low rates of CHD in premenopausal women is their low bodily iron stores; in elderly males and females, elevated cholesterol is often associated with greater longevity).
Pee Pee focuses on a microscopic portion of my writings, which he thinks can be belittled enough to support his case, and blissfully ignores everything else. This evidence is so copious I was able to fill a 450+ page book with it (and, believe me, I could have written much, much more…). Searching around on the Internet, this term seems to be most commonly employed as a misspelling of the ancient Chinese philosophy, Confucianism. This anonymous sleazeball is more than willing to denigrate others who are genuinely trying to alert people to damaging health myths, but then turns around and vigorously defends one of the most damaging and fraudulent health myths of all time. However, after excluding the results of the poorly designed and sloppily-conducted northern European studies, it quickly becomes apparent that there does not exist a single tightly-controlled trial which shows that saturated fat restriction can save even a single life. The Rose et al, Anti-Coronary Club and Sydney Diet Heart studies all showed significant increases in overall mortality from replacing animal fats with omega-6-rich vegetable fats. Defenders of cholesterol lowering have complained that these trials could not have reduced serum cholesterol to a large enough degree. Among the remainder of the participants who were free of CVD at baseline, there were no significant differences in CHD or stroke incidence, CHD or stroke mortality, or total mortality during an average 8.1 years of follow-up. Researchers have observed individuals with very low cholesterol levels whose arteries were riddled with atherosclerosis, and individuals who had high cholesterol levels yet relatively disease-free arteries. What these populations did do was avoid the chronic stresses of modern societies, eat a diet of natural whole foods, and get plenty of physical activity. The above-mentioned lack of association in older Framingham adults was for those whose cholesterol levels had remained constant. The authors tried to dismiss this astounding revelation by claiming; "After age 50 years the association of mortality with cholesterol values is confounded by people whose cholesterol levels are falling--perhaps due to diseases pre-disposing to death".
Firstly, the considerable fourteen-year time lag employed by the researchers weighed heavily against the possibility of cholesterol reductions occurring due to the development of disease.
And again, in true Pee Pee fashion, he pretty much ignores the multitude of evidence showing otherwise.
Performance on a sustained attention task was significantly worse among those who reduced their cholesterol during the trial(19). At the start and at the conclusion of the study, subjects were given a battery of tests assessing attention, psychomotor speed, mental flexibility, working memory, and memory retrieval. Similarly, ratings of depression declined slightly during the high-fat period, but increased during the low-fat period, mainly due to two of the low-fat subjects reporting significantly greater depression-dejection ratings. These results were adjusted for age and sex, and persisted even after excluding the first five years of follow-up, those who were unemployed, and those who had been treated for depression(27). In terms of CHD prevention and treatment, everything seems to revolve around lowering cholesterol. The cholesterol theory isn’t delivering, and until modern medicine changes its focus to what does work, millions of people will continue to die unnecessarily from heart disease each year.
But doctors have been so brainwashed by the bullshit cholesterol theory they go ahead and prescribe them to women every day, thus needlessly exposing them to all the potential side effects of these toxic drugs.
In April of 2002, Barker was a healthy and physically fit fifty-four year old who watched his diet and walked twenty-five kilometers each week. On the morning of June 23, 2002, Barker sat eating his breakfast and reading the Sunday paper, just as he had done countless times before.
How does it feel to be so wedded to dogma that you’ll happily defend a rotten, invalid paradigm that KILLS PEOPLE?
What is it about people that makes them virulently attack someone who’s telling them the truth, while rabidly defending someone who’s screwing them up the ass?
Amount of fat in the diet affects bioavailability of lutein esters but not of {alpha}-carotene, {beta}-carotene, and vitamin E in humans. A Randomized, 4-Month Mango and Fat Supplementation Trial Improved Vitamin A Status among Young Gambian Children. Lutein Bioavailability Is Higher from Lutein-Enriched Eggs than from Supplements and Spinach in Men.
Carotenoid bioavailability is higher from salads ingested with full-fat than with fat-reduced salad dressings as measured with electrochemical detection. Carotenoid Absorption from Salad and Salsa by Humans Is Enhanced by the Addition of Avocado or Avocado Oil. Randomized trial of the effects of cholesterol-lowering dietary treatment on psychological function. Comparative effects of pravastatin and lovastatin on nighttime sleep and daytime performance. Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults. Higher Prevalence of Depressive Symptoms in Middle-Aged Men With Low Serum Cholesterol Levels.
A key benefit of generic drugs is that they usually cost a fraction of the price of brand-name drugs, as much as 80% to 85% less according to the US Food and Drug Administration. Patent protection generally protects a drug’s intellectual property rights for about 20 years, but as the patent is effective from the clinical trial stage, the actual time the drug is on the market can be far less, often between 10 and 14 years. The FDA acts as a governing body for generic drugs to enforce maximum standards of variation with brand-name drugs.
In October 2011 Zyprexa, used to treat bipolar disorder and schizophrenia, will come off patent leaving the door open for generic Olanzapine. Clopidogrel, used to prevent blood clots and ward off strokes and heart attacks, will be able to take some of Plavix’s market share.
Japan is likely to see over 12% growth to exceed $9.5 billion in 2014, reports BCC Research. For more details about Endocrine System Charts and also see below some important list of products in Endocrine System Charts . I religiously ate a very low fat diet, avoided saturated fats like they were some kind of flesh-eating virus, and ate lots of “healthy” whole grain foods in accordance with the reigning cholesterol-phobic dogma.
All I seem to get is whiny little dickwads like Pee Pee publicly accusing me of being a fringe charlatan. Give the population tits, booze, drugs, celebrity gossip, NASCAR, football and cricket, and a bunch of fabricated enemies to rally against, and they’ll pretty much do whatever you want them too. Seize every opportunity to garner publicity by acting like a shameless skank, and be sure to post a porn video on the Internet of yourself getting worked over by some similarly shameless goofball. Oh wait a minute, you’ve got a thing about the Swedes, so let me save you the trouble and give you the answer straight up: BUGGER ALL. Have you ever considered that maybe they have a vested interest in keeping this unscientific sham alive?
Yep, little old me is actually the Goliath in this fight, while the multi-trillion dollar cholesterol behemoth is actually the David, the poor little underdog that doesn’t get a fair hearing because my book, which most doctors and journalists have never heard of, is completely crowding out their humanitarian message. In fact, I've written ad nauseum, in my books and on this site, that epidemiological studies can never be considered to prove anything, that association is not causation. At the time of his Six Countries charade, data on fat intake and mortality was actually available for 22 countries. Like the Holmberg study, which Pee Pee doesn’t like because it involves Swedish farmers in their sixties and is also non-supportive of the cholesterol theory. I didn’t create or “abuse” the J-Curve, my friend, I’m merely factually reporting what researchers found in a multitude of studies over which I had absolutely no influence whatsoever.
And while Pee Pee’s beloved statin drugs have shown limited usefulness in men, they do absolutely nothing to reduce mortality in women. The only actual definition I could find was a tongue-in-cheek one courtesy of Wikipedia parody site Uncyclopedia: “Confusionism is a Far Eastern religion that started out as an elaborate way to way to state the blindingly obvious before it developed into an after dinner game about following orders". The longest-running study focusing on saturated fat restriction (the Los Angeles Veterans study) showed a significant increase in cancer mortality among the intervention subjects--despite their lower rate of smoking!
Not only does their argument reek of wanting to shift the goal posts after failing to score, it directly contradicts their cherished and oft-repeated dogma that a one percent reduction in serum cholesterol translates to a two percent reduction in CHD risk.


But instead of examining these populations to see what valuable lessons they can teach us, Pee Pee simply pretends they never existed. In 1987, the researchers heading the famous Framingham Study published a thirty-year follow-up paper, reporting on the incidence of all-cause mortality and cardiovascular disease mortality. Those whose cholesterol levels had decreased during the study experienced an increase in both total and CVD mortality. This unconvincing piece of doublespeak inferred that people over 50 were dying of diseases that also happened to lower their cholesterol levels. Secondly, CVD mortality, which includes deaths from CHD and ischemic stroke - the very diseases that are supposedly caused by high cholesterol levels - increased to a greater degree than overall mortality! As with visuomotor speed, the ability to maintain divided attention is essential for safe driving. After six-months' month follow-up, the placebo group had improved significantly in all five domains of cognitive function, but the lovastatin group improved only on memory recall tests(21).
HDL cholesterol levels declined during the low-fat period, a typical response on low-fat, high-carbohydrate diets, indicating that subjects ate the foods as supplied. Levels of tension-anxiety declined during the high-fat period, but did not change during the four weeks of low-fat eating. Little dent has been made in the incidence of heart disease; it still rivals cancer as the main cause of death in modernized countries all around the world. He did take some medication for mild hypertension, but otherwise showed no sign of any heart trouble.
His recovery after the treadmill session was excellent, and ultrasound images showed no sign of blockage to his arteries.
It was after finishing his second piece of toast that he felt a sudden pain shoot through the base of his spine.
I met Brian and his wife Heather in Sydney five years ago, when Uffe Ravnskov visited Australia.
Children's consumption of dark green, leafy vegetables with added fat enhances serum retinol.
Serum retinol concentrations are affected by food sources of ?-carotene, fat intake, and anthehelmintic drug treatment. Effects of level and source of dietary fat on the bioavailability of iron from turkey meat for the anemic rat.
Effect of dietary linoleic acid on the tissue levels of zinc and copper, and serum high-density lipoprotein cholesterol. Interactions among dietary fat, mineral status, and performance of endurance athletes: a case study. Effect of variations in fat and linoleic acid intake on the calcium, magnesium and iron balance of young men. Dietary linoleic acid influences desaturation and acylation of deuterium-labeled linoleic and linolenic acids in young adult males. Dietary saturated fat level alters the competition between alpha-linolenic and linoleic acid. After a patent expires, pharmaceutical companies come under fierce pricing pressure due to competition from their less-expensive generic counterparts. However, in an 11-year study, variation in absorption of branded and generic drugs was found to be as little as 3.5%. My reward was a number of adverse health effects including elevated blood pressure and a screwed up blood sugar metabolism. Yep, I’m just a money-hungry charlatan looking to add to my warehouse full of Lamborghinis, my flotilla of multi-million dollar yachts, and my collection of private islands.
They’ll probably even make a movie about you, based on your best-selling book (I Killed the Cabbage: The Life and Times of Vegetable Standover Man Pee Pee “Bones” Broccolini).
Hey, I never said humans make sense, all I know is it worked for Atkins, Taubes, Eades, Dr Phil and a bunch of others! He does it because he really believes the cholesterol theory is a harmful and misleading sham. The AHA Heart Check does not come for free my friend, it can only be displayed on items whose manufacturers have paid $7500 each (quantity discounts available!). The simple fact is that no other banana consortium has struck a deal to pay the AHA money each year to endorse their produce.
I simply gave the Holmberg study a brief mention and factually reported the findings with little fanfare. He belittles the lead author of this study because no-one else but her has cited the study in their papers. In a sane, intelligent, rational world, people like Pee Pee would be immediately identified as fringe lunatics and sentenced to life imprisonment in Soyberia, a lonely, barren vegan shithole thousands of miles away from the nearest Internet connection. Higher fat diets and higher fat meals have repeatedly been shown to improve nutrient absorption, including that of the vitamins, mineral, and carotenes found in plant foods. When a pair of non-biased researchers subsequently plotted the data for all 22 countries on a graph, instead of just six, guess what happened to Keys’ strong, positive, linear association between fat intake and mortality? There have been a number of meta-analyses and reviews since then that have concluded saturated fat has bugger all association with heart disease.
In other words, those who ate the highest amounts of saturated fat had no greater risk of CVD than those who ate the lowest. That gave Pee Pee plenty of time to read and discuss another study I wrote about on my site on October 5, 2011.
And if you re-read the female results from the study discussed above, you’ll see that there was no J-curve when it came to CVD and overall mortality, but rather a simple linear association: as cholesterol went up, mortality went down. But Pee Pee doesn’t give a hoot about any of that…no sirree, he evidently thinks women should shut up, learn their place, and eat a tasteless diet of low-fat shit and take their useless statin drugs like everyone else.
What on Earth has this got to do with people who point out the cholesterol theory for the complete sham that it is?
The researchers found that higher cholesterol levels were associated with increased mortality before the age of fifty, but after this age cholesterol levels in men and women showed no relationship with CVD or total mortality. When Muldoon and his team subsequently performed another study, this time using simvastatin, they obtained similar results.
After four weeks had passed, the groups were swapped around so that those originally on the low-fat diet were consuming the high-fat diet, and vice-versa. Sorry folks, but as disgusted as I get with my fellow humans sometimes (OK, a lot of the time), I couldn’t even begin to embrace such a genocidal viewpoint.
His younger brother, however, had not been so fortunate, having already endured a heart attack and triple bypass surgery. Both Brian and Heather were nice folks, and I couldn't help but feel for Brian; the once healthy Kiwi now had to live with the kind of physical mannerisms and impaired speech typical of stroke victims. Being one of these weird people with the ability to question what he’s been told when it proves untenable, I began researching the whole anti-saturate, anti-cholesterol phenomenon. Young women will want to be just like you, which in turn will open a plethora of lucrative new marketing opportunities! Have you ever stopped to look at the financial ties of these people at the end of the published lipid guideline updates?
But listening to Pee Pee, you'd think the Holmberg study is the centrepiece of my case against the lipid hypothesis.
Is it really a stretch to believe that maybe the higher dairy fat content was improving absorption of heart healthy nutrients?
The studies involved in these reviews encompassed a wide variety of populations and age groups.
He mentions a single study and writes me off as a “professional” “cholesterol confusionist”. The Framingham study is hardly alone in demonstrating that cholesterol is not a risk factor for older folks.
Failure to improve on cognitive tests was observed with both ten and forty milligram doses of simvastatin(22).
Throughout the study, all meals were prepared by the university conducting the study and supplied to the participants. To any rational observer, Barker would hardly have seemed like a suitable candidate for powerful cholesterol-lowering drug therapy. His legs felt weak, his complexion turned gray, his speech became incoherent, and his eyes became glassy. Supplement your statin use with red rice yeast extract, which has also been shown to cause rhabdomyolysis. As your piece de resistance, when you are fortunate enough to meet a guy who for reasons unknown still wants to marry you, despite your sleazy past and the fact that he could do a damn sight better, go ahead and tie the knot – just make sure you untie it only 72 days later! Have you ever stopped to consider that their extensive financial ties to the manufacturers of cholesterol-lowering drugs might skew their impartiality, you know, just a little? For example, it is replete with products high in cereal fibre which have never been shown to be heart healthy; as I have explained elsewhere, clinical trials have actually shown cereal fibre to increase CHD mortality and colorectal cancer incidence.
And supplying extra amounts of important nutrients, like omega-3 fats and vitamin A, directly?
Study upon study has repeatedly shown that higher cholesterol levels do not increase the risk of CHD, nor stroke, nor overall mortality, in seniors.
However, despite his highly positive test results, Barker 's doctor decided that - "as an extra precaution" - he should start taking simvastatin on a daily basis. His wife Heather wrapped him in a winter jacket, put a duvet around him, and turned the heater on, but Barker still continued to shake.
Hey, this “Release Your Inner Ho!” approach worked just fine for Kim Kardashian, Paris Hilton and Madonna…why not you? Popcorn, pancake mix, crackers, high-GI fruit juices, and processed meats are some of the other “heart healthy” items to be found on the AHA list. Incredibly, I discuss two of these in the same post right above the Swedish farmers study that Pee Pee wanks on about, but he makes absolutely no mention of them!
In fact, several studies have found that higher cholesterol levels are predictive of increased survival and greater longevity in older age groups. Barker dutifully obeyed and started taking twenty milligrams of the widely prescribed statin every night.
Twenty minutes later, he got up and staggered towards the toilet, where he proceeded to vomit violently. Lather your food in margarines and polyunsaturated vegetable oils rich in cholesterol-lowering and cancer-causing linoleic acid. Five days after becoming abruptly ill, the drained and dehydrated Kiwi was hospitalized with acute kidney failure. He was suffering from life-threatening rhabdomyolysis, courtesy of the simvastatin that had been prescribed "as an extra precaution" against heart disease.



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