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Hist-Zyme is a patented enzyme formula containing diamine oxidase  (DAO)—the main enzyme responsible for the degradation of ingested histamine. Histamine is a bioactive or “vasoactive” amine produced in the body in response to an injury or foreign substance.
Histamine is not only produced in the body but is also present in many fermented foods, such as sauerkraut, sausage, cheese, yogurt, and alcoholic beverages. Ultimately, diminished serum DAO levels appear to be associated with changes in histamine degradation and serum histamine levels.[10]Although the mechanism of histamine degradation is uniform throughout the body, Hist-Zyme only addresses excess exogenous histamine found in the folds, villi, and microvilli of the small intestine. Take one to two capsules no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare practitioner. Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
References*These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure, or prevent any disease.
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Uptime Energy is a new energy drink that promises to boost both your mental and physical energy. Uptime Energy is an energy-boosting beverage that was just recently released onto the internet.
Despite the new and improved appearance, these are the same Uptime Energy capsules that have been sold at gas stations across America since 1985.
The company recently underwent a rebranding campaign and released a new energy beverage along with its classic lineup of energy tablets.


The Uptime Energy beverages come in distinctive 355mL black and white bottles while the tablets come in packages of 3 tablets. The Original recipe is flavored with natural, cane sugar, while the Sugar Free recipe has 0 sugar. The flavor is best described as being a blend of orange, lemon, and lime flavors – kind of like 7-Up or Sprite with a bit of an orange twist. Unlike many energy drinks and coffee beverages, Uptime Energy also contains additional nootropic-like ingredients designed to promote healthy brain activity and boost your cognitive energy. There are two versions of the Uptime Energy Capsules, including the Original Energy Blend and the Maximum Energy Blend. You take three capsules at once to support a sustained release of energy (the manufacturer recommends taking one capsule per every 50 pounds of body weight). Essential Oil of Peppermint Capsules proving on average 50mg of Essential Oil of Peppermint.
Disclaimer:Always read product information, including warnings, directions and ingredients contained on actual product labels before using. This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract. It has an array of physiological effects, including increasing blood supply to specific sites in the body.
Tuna, olives, spinach, eggplant, avocados, tomatoes, cherries, and citrus fruits are other histamine-containing foods.
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The capsules come with “premium vitamins, herbs and minerals” and are designed for those who want to boost their energy while on-the-go. The company recently underwent a much-needed rebranding campaign, however, which is why many people think that it’s a brand new product.
Despite their absence of histamine, some foods, such as berries, tea, and a variety of spices, stimulate the endogenous production of the amine due to their benzoate content.
A twocapsule dose of Hist-Zyme contains 20 mg of vitamin C, 200 mg of calcium, and 20,000 HDU (histamine degrading units).
Histamine intolerance-like symptoms in healthy volunteers after oral provocation with liquid histamine. Both catabolic pathways of histamine via histamine-N-methyltransferase and diamine oxidase are diminished in the colonic mucosa of patients with food allergy.
Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities. Evidence for a reduced histamine degradation capacity in a subgroup of patients with atopic eczema. WWSM accepts no liability for inaccuracies in information given, or provided by manufacturers, nor for any loss or damage that may arise from use of the information contained within material on this website.



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