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Bile acids stored in the gallbladder, and released into the small intestine after feeding to promote the absorption of lipids and lipid-soluble vitamins, have been shown to have a direct impact on the microbiota of the small intestine5. Similarly, products of the intestinal microbiota have a direct impact on hepatic function as byproducts of bacterial metabolism can produce a number of hepatotoxic substances, such as ammonia, ethanol, acetaldehyde, phenols, and benzodiazepines, all of which must subsequently be metabolized by the liver2.
The contents of this website are intended for business to business customers, healthcare professionals and investors only. The length of time for the expiration date or "best used before" date depends on the type of product, as well as the brand.
Perishable items (such as flax oils or certain probiotics) generally have shorter expiration dates.
Our receiving department does its best to verify and then enter the correct expiration dates for all incoming products.
The Shipping Weight includes the product, protective packaging material and the actual shipping box.
As a dietary supplement for adults, take one (1) to two (2) vegetable capsules daily, preferably at mealtimes, or as directed by a healthcare practitioner. Advanced Multi-Billion Dophilus Complex (Maltodextrin, Microcrystalline Cellulose, Cultures, Sodium Alginate, Silica, Vegetable Magnesium Stearate), Vegetable Cellulose.
Solgar's Advanced Multi-Billion Dophilus Vegetable Capsules are free of sugar, salt, starch, yeast, wheat, soy, dairy products and gluten and are formulated without the use of artificial preservatives, flavors or colors.
If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement. Become an iHerb customer and earn unlimited Rewards by sharing your favorite iHerb products with others.


Red Yeast Rice is a unique natural product that's been used in Asian traditional medical systems since approximately 800 A.D. Do not use if you are pregnant, may become pregnant, or are breastfeeding, because using this product may harm the fetus. The gut and the liver are intimately associated, and there is continuous bidirectional communication between these organs through the bile, hormones, inflammatory mediators, and products of digestion and absorption1. In both animal models and humans, obstruction of the flow of bile acids is associated with proliferation of colonic bacteria and mucosal injury, which can lead to translocation of bacteria through the mucosal barrier and systemic infection. Furthermore, bacterial lipopolysaccharide (LPS), when released from intestinal Gram-negative bacteria, binds to LPS-binding protein, which then binds to CD14 on Kupffer cells. Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Although our warehouse is fully air-conditioned, these more fragile items are put in cold storage (freezer or refrigeration unit) for maximum freshness. Although it is not required, refrigeration helps to further preserve the probiotic microorganisms. Produced by fermenting red yeast (Monascus purpureus) with white rice, Red Yeast Rice is commonly used in cooking applications to enhance the color and flavor of foods. Consider taking this product in combination with NOW CoQ10, Sytrinol and Silymarin (Milk Thistle Extract). Individuals with liver disease or those currently taking statins or other medications should consult with a health practitioner prior to use. Therefore, the quantity, quality, and composition of the colonic microbiota can be expected to have both direct and indirect effects on liver function and physiology and possibly liver disease progression.


Although the mechanisms through which bile acids inhibit bacterial overgrowth are still being explored, available data clearly suggest that products of the liver can directly influence the composition and effects of the intestinal microbiota6.
Association between CD14 and Toll-like-receptor 4 (TLR4) on the cell surface triggers an inflammatory cascade, including stress-activated and mitogen-activated protein kinase, c-Jun N-terminal kinase (JNK), p38, and the nuclear factor-?B pathways, suggesting that the intestinal microbiota can indirectly mediate inflammation within the liver2. This being said, the exceptionally high turnover at iHerb ensures that our inventory is among the freshest in the industry. This relationship was demonstrated more than 80 years ago when alterations in the gut microbiota of patients with chronic liver disease were reported2. NOW Red Yeast Rice is carefully produced to avoid the presence of citrinin, a sometimes toxic by-product of the fermentation process.
Since that time, significant advances have been made that directly link the composition of the colonic microbiota to liver diseases3.
As an examble, recent data have shown that small intestinal bowel overgrowth (SIBO) is a common feature in patients with cirrhosis and is correlated directly with the severity of liver disease4. As such, these products will reflect a higher Shipping Weight compared to the unprotected product. This product is formulated to protect these organisms from stomach acidity, helping to maintain a healthy intestinal flora.



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