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28.07.2015

Symptoms of addison's, chronic daily fatigue - .

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Addison’s disease is a disorder that occurs when your body produces insufficient amounts of certain hormones produced by your adrenal glands.
Also called adrenal insufficiency, Addison’s disease occurs in all age groups and affects both sexes.
Treatment for Addison’s disease involves taking hormones to replace the insufficient amounts being made by your adrenal glands, in order to mimic the beneficial effects produced by your naturally made hormones. Your doctor can help determine whether Addison’s disease or some other medical condition may be causing these problems. Addison’s disease results when your adrenal glands are damaged, producing insufficient amounts of the hormone cortisol and often aldosterone as well.
If you have untreated Addison’s disease, an addisonian crisis may be provoked by physical stress, such as an injury, infection or illness. Write down any symptoms you’re experiencing, including any that may seem unrelated to the reason for which you scheduled the appointment.
An addisonian crisis is a life-threatening situation that results in low blood pressure, low blood levels of sugar and high blood levels of potassium.
Addison's disease is a rare endocrine, or hormonal disorder that affects about 1 in 100,000 people.


Addison's disease occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. Most cases of Addison's disease are caused by the gradual destruction of the adrenal cortex, the outer layer of the adrenal glands, by the body's own immune system. This form of Addison's disease can be traced to a lack of ACTH, which causes a drop in the adrenal glands' production of cortisol but not aldosterone. Because the symptoms progress slowly, they are usually ignored until a stressful event like an illness or an accident causes them to become worse. In patients suspected of having an addisonian crisis, the doctor must begin treatment with injections of salt, fluids, and glucocorticoid hormones immediately. Treatment of Addison's disease involves replacing, or substituting, the hormones that the adrenal glands are not making. During an addisonian crisis, low blood pressure, low blood sugar, and high levels of potassium can be life threatening.
In Addison’s disease, your adrenal glands produce too little cortisol and often insufficient levels of aldosterone as well.
Measuring your blood levels of sodium, potassium, cortisol and ACTH gives your doctor an initial indication of whether adrenal insufficiency may be causing your signs and symptoms.


About 70 percent of reported cases of Addison's disease are due to autoimmune disorders, in which the immune system makes antibodies that attack the body's own tissues or organs and slowly destroy them.
A review of a patient's medical history based on the symptoms, especially the dark tanning of the skin, will lead a doctor to suspect Addison's disease. A blood test can also measure antibodies associated with autoimmune Addison’s disease. In most patients, symptoms are severe enough to seek medical treatment before a crisis occurs.
However, in about 25 percent of patients, symptoms first appear during an addisonian crisis. Skin changes also are common in Addison's disease, with areas of hyperpigmentation, or dark tanning, covering exposed and nonexposed parts of the body.
A person with Addison's disease also should know how to increase medication during periods of stress or mild upper respiratory infections.



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