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02.04.2014

Problems with sleeping pills, cfs/me - PDF Review

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With around 30% of the US population experiencing symptoms of insomnia, it is no wonder that the use of prescription sleeping pills is common. As a result, many patients are prescribed sleeping pills when they are discharged from the hospital, as well as diuretics, antihypertensives, anticoagulants, antiarrhythmics and antiplatelets.
Sleeping pills may increase the risk of hospital readmission and cardiovascular-related death for patients with diastolic heart failure, according to researchers. Patients were divided into two groups; those with preserved ejection fraction (HFpEF) - referred to as diastolic heart failure - and those with reduced ejection fraction (HFrEF) - referred to as systolic heart failure.
Further investigation revealed that HFpEF patients who were prescribed sleeping pills were eight times more likely to experience hospital readmission for heart failure or suffer cardiovascular-related death, compared with HFpEF patients who were not prescribed sleeping medication. The team found no association between sleeping pills and increased risk of cardiovascular-related death and hospital readmission among HFrEF patients. However, the team found that HFrEF patients who were prescribed medication for high blood pressure - including ACE (angiotensin-converting enzyme) inhibitors or angiotensin receptor blockers - had less than one quarter the risk of experiencing cardiovascular events, compared with HFrEF patients who were not prescribed high blood pressure medication. Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional.
On the surface, prescription sleep aids can seem like the perfect cure for insomnia: Take a pill, and a few minutes later you slip into a restful sleep. When you take prescription sleeping pills over a long period of time, your body grows accustomed to the drug, and you need higher and higher doses to get the same sleep-inducing effect. New data has revealed that people who take certain forms of the sleeping pill zolpidem (Ambien) may still have enough of the drug in their bodies in the morning to impair activities like driving.


We’ve all been known to do strange things in our sleep, but prescription sleeping pills, particularly benzodiazepines such as triazolam, have been known to cause side effects like sleepwalking and amnesia. People who took prescription sleeping pills were more likely to die or get cancer than those who did not take them, according to a 2012 study published in BMJ Open.
Once you begin taking sleeping pills, it can be hard to stop, particularly if you’ve been taking them for a long time. The study compared the medical records of more than 10,000 people prescribed sleeping pills and 23,000 similar people who had never been prescribed sleeping pills. Meet our StaffOur staff is comprised of nationally-recognized physicians and expert support staff all focused on prevention, wellness, and developing lasting, personal relationships with each and every patient.
But for patients with diastolic heart failure, such medication may significantly increase the risk of cardiovascular events.
Masahiko Setoguchi of the Social Insurance Central General Hospital in Tokyo, Japan, says that sleeping problems are a common side effect of heart failure. Therefore, they wanted to investigate whether the drugs that patients are prescribed at discharge are associated with hospital readmission and cardiac events.
Ejection fraction is a measurement of the volume of blood pumped out of the left and right ventricle with each heartbeat.
On comparing patients who reached study endpoint with those who did not, they found differences in prescription of sleeping pills (benzodiazepine hypnotics), blood sodium levels at hospital admission and blood hemoglobin levels at discharge.
Setoguchi notes that larger studies among HFpEF are needed to confirm the findings, so heart failure patients should not be advised to stop using sleeping medication just yet.


Though they do have legitimate uses, sleeping pills also come with significant risks and side effects, which many people don’t realize, says Marc Leavey, MD, a doctor of internal medicine at MD Mercy Hospital in Baltimore. Some people experience “rebound insomnia” — when sleeping problems actually worsen once you stop taking the drug. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem, National Academic Press, 2006.
This is because both the drugs and the risk of death could be associated with other factors, such as lifestyle or other medical problems, which the researchers tried to adjust but cannot fully rule out. These medicines are not intended for long-term chronic use and could be particularly hazardous in those with risk of falls, undiagnosed or untreated sleep apnea, elderly patients, or in combination with other sedating agents including alcohol, narcotic pain medicines or certain anxiety medications. To minimize your risk for this side effect, don’t take sleeping pills for longer than a week or two.
If you want to go off your sleeping pills, talk to your doctor about setting up a schedule to gradually reduce your dosage, rather than just quitting cold turkey. Sleeping in one or two days a week or over the weekend may actually upset your natural body clock.
Serious health conditions have been associated with severe, chronic lack of sleep, including obesity, high blood pressure, diabetes, heart attack, and stroke.



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