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Me disease life expectancy, slight ringing in both ears - For Begninners

Author: admin
The later the age of onset for a genetic disease, the more it will overlap with these curves. For me, at least, the easiest way to visualize the censoring of observed individuals is to plot the age of onset PDF over the life expectancy PDF.

In other words, the later the age of onset, the more people will already be dying of other causes by the time the genetic disease comes to get them. A thorough analysis using actuarial life tables concluded that, just as in my simulation here, the penetrance is complete as long as you don’t die of something else first [Spudich 1995 (ft)].

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