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Medical history, your current and past these abnormalities include hypothyroidism, hyperthyroidism, hyperlipidemia because of the multifactorial nature.


Is major depression a mood disorder, how to cure ear ringing naturally - Review

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In past depression was described as anyone experiencing hopelessness, helplessness and worthlessness. There are several theories that try to explain the genesis of depression but what is accepted is that the cause of depression is multi-factorial. Biogenic Amines- There are two major amines that have been implicated in causation of depression and other amines are still being investigated. Neuroendocine Regulation- A correlation between the hyper secretion of cortisol and depression is one of the oldest theories of depression. According to cognitive theory people with depression tend to form cognitive distortions which include developing negative views about self, environment and future.
Features 1-3 are classified as core symptoms and two of these three have to be present for at least two weeks to make a diagnosis of depression.

Mild Depression- At least 2 out of the three core symptoms for two weeks with at least 2 of the remaining symptoms.
Moderate Depression- At least 2 out of the three core symptoms for 2 weeks with at least 3 of the remaining symptoms. Severe Depression- At least 2 out of the three core symptoms for two weeks with at least 4 of the remaining symptoms. This would include looking at their upbringing, bereavement and also completing some mood and anxiety scales for baseline and to judge progress and improvement. Although helpful but it lead to the over use of the word depression and anybody having a bad day would say that they are depressed. The lack of Serotonin and Noradrenaline availability at receptor sites in the brain leads to depression.

Hypothyroidism is one of the most common disorders found in depression and should always be looked for. There is almost 2 fold more incidence of major depression in females as compared to males in different cultures.
Thyroid function tests and blood sugars are also important as hypothyroidism and diabetes can both predispose and precipitate depression.

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