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13.06.2014

Bipolar disorder definition in spanish, ayurvedic home remedies tinnitus - Plans Download

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DefinitionBipolar disorder is a condition in which a person has periods of depression and periods of being extremely happy or being cross or irritable.
In addition to the adverse psychosocial, vocational, and societal impacts of BPD, the lifetime suicide rate associated with BPD (15.6%) is higher than corresponding rates in any other psychiatric disorder. The mood symptoms in the first two criteria are not better accounted for as schizoaffective disorder and are not superimposed on schizophrenia, schizophreniform disorder, delusional disorder, or psychotic disorder not otherwise specified.
Adapted from American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed, text rev. If an active mood episode is identified, rule out mood disorder due to a general medical condition or one that is substance-related.
If psychosis accompanies a mood episode, rule out schizophrenia, schizoaffective disorder, delusional disorder, or psychosis due to a general medical condition. OFC is the only FDA-approved treatment for acute bipolar depression and delivers both antidepressant and antipsychotic medications simultaneously in one preparation. Neither is currently FDA approved for this indication, and the strength of the data supporting their use for bipolar depression is modest at best. Maintaining a strong working alliance with the bipolar patient typically requires additional time, effort, and skill. Treatment strategies must be individualized and adjusted at different phases of the mood disorder. Olanzapine-fluoxetine combination (OFC) and mood stabilizers are first-line treatments for bipolar depression.


Ryan MM, Lockstone HE, Huffaker SJ, et al: Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes. Valtonen HM, Suominen K, Mantere O, et al: Suicidal behaviour during different phases of bipolar disorder.
Calabrese JR, Keck PE Jr, Macfadden W, et al: A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression. Ghaemi SN, Miller CJ, Berv DA, et al: Sensitivity and specificity of a new bipolar spectrum diagnostic scale. Dr Vieta led a study to create new definitions and algorithms for the management of treatment-resistant bipolar I and bipolar II depression.1 He created the algorithms after encountering many patients within his practice who had bipolar disorder, were depressed, and did not respond to standard treatments. A higher rate of mood and anxiety disorders exists in the first-degree relatives of persons with BPD than in the general population. A diagnosis of bipolar I disorder is given if there has been at least one lifetime episode of mania or a true mixed episode; a diagnosis of bipolar II disorder depends on at least one lifetime episode of hypomania, with none of the episodes achieving criteria for mania. Antidepressants, when prescribed alone, are not effective for bipolar depression and are not formally indicated for such use by the FDA. Investigation of quetiapine (Seroquel) as monotherapy for bipolar depression has produced promising results and might receive FDA approval in the near future. Their off-label use is nevertheless recommended, given the paucity of effective treatments for bipolar depression. Once this mood disorder has declared itself, the patient should be counseled regarding the chronic risk for relapse and recurrence; lifetime treatment is recommended.


The Bipolar Spectrum Diagnostic Scale (BSDS) involves an easy-to-read, one-page story that depicts typical mood swing experiences.
In contrast, the postpartum period is associated with increased risk for bipolar relapse and illness onset.
This may have led to an overdiagnosis of BPD, which until recently was underdetected or misdiagnosed as recurrent major depressive disorder (MDD). The pattern is not the same in all persons with bipolar disorder:Depression and mania symptoms may occur together. The natural course of bipolar disorder is for episode frequency to gradually increase and for an ever-increasing percentage of episodes to be characterized by depression.
Because these potential adverse outcomes are not unique to olanzapine and are regarded as an effect of the atypical antipsychotic class, OFC should be considered as a first-line treatment for bipolar depression. In general, late-onset mania suggests drug toxicity or an underlying medical disorder until proved otherwise. But it occurs more often in relatives of people with bipolar disorder.In most people with bipolar disorder, there is no clear cause for the periods (episodes) of extreme happiness and high activity or energy (mania) or depression and low activity or energy (depression).



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