28.05.2015

What is the prognosis for stage 4 renal cell carcinoma

Overall prognosis depends on the grade and the stage of the cancer and also on the overall performance status of the individual at the time of diagnosis and treatment. Generally, if the cancer is at stage 1 at diagnosis, the prognosis is good because a complete surgical resection of the cancerous growth is possible.
To be honest, I’m getting more anxious and a little more confused about my situation. Last Spring I was diagnosed with stage 3a grade4 RCC that had not spread beyond the kidney wall – but my 2 regional nodes and the adrenal gland were also removed. My oncologist is a smart man, a John Hopkins man, but I feel like a lab rat, and they screw up my appointments and make me feel like I’m just lucky to attend such a hospital.
Now I am experiencing an ache in the area of the nephrectomy … should I be considered? Had a partial nephrectomy 2008; resected a gulf ball size cancer tumor was able to keep 60% of left kidney with adrenal gland. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. Synchronous bilateral testicular neoplasm is a rare situation, involving about 2% of patients.[3,4]To the authors' knowledge, we report the first case of a patient affected by synchronous testicular cancer of different histology. 25% of patients are diagnosed while at stage 4 of the disease and when this happens barely 10% make it to 5 years. This is important because a poor overall performance means symptoms like fever, weight loss and extreme tiredness that inhibit treatment. Last year I had a complete radical nephrectomy on my left kidney doctor said he got all the cancer out. Unfortunately 5 mos later I now have a 5cm RCC tumor in my right humerus where it has spread to my bones.
When I was 54 I was diagnosed with renal cell and underwent a nephrectomy of my left kidney and also lost several inches of colon to which the tumor was attached.
I had been getting ultrasound scans for bladder problems for about 3 years, to check the urinary function.
This new and challenging clinical situation, as well as the various treatment options, will be discussed.Case History and InvestigationsA 36-year-old male presented to his primary care practitioner with bilateral testicular swelling. However, it must be noted that even at this stage if the cancerous tumor is of a low grade and is localized, the kidney cancer survival rates can be as high as 40%. At stage 3 the kidney cancer survival rates begin to diminish because the cancer would have spread to the nearby lymph nodes, the survival rate drops to 40 – 70% for 5 years.  At stage 4, if the cancer has metastasized  to the other organs of the body, the overall 5 year survival rate is barely 5%, but if it has not metastasized, the survival rate can be higher. Now I had a biopsy done because a ct scan showed a mass which there is a large mass in the same spot the kidney was removed renal cell carcinoma it is called.
We saw her jump from Stage 1 to Stage 4 in 5 months, unfortunately my Mother passed on March 11, 2011!
I was being treated for a vitamin D deficiency and a very slightly elevated calcium level and the RCC was eventually discovered via a CT scan. Three months later, the cancer had spread to my lungs, soft tissue where the kidney had been and to bone (rib).


He is a father of one child (6 years old) and has unsuccessfully tried to conceive for the past 6 years. Now the doctor wants to operate and try to take this cancer mass out which is also started to attach to the muscle so he will also have to shave away some of this and told me it is a very big surgery and recovery could be weeks maybe months but says there is no other treatment i can have done for this. I underwent high dose Interleukin 2, immune response therapy three months later and within two months (May 1999) a CT showed no more tumors (not lungs, not soft tissue, not bone). The patient has a history of cryptorchidism of the right side, treated with orchidopexy at the age of 4. Ries LAG, Melbert D, Krapcho M, et al: (eds) SEER Cancer Statistics Review, 1975–2004, National Cancer Institute. The cancer mass is contained and not moved to any other parts of my body, should i go to a cancer treatment hospital for further treatments or solutions to this problem or listen to the doctor and have the surgery. I am walking, although I appear at times a bit like a drunken chicken when trying to get around.
I am slightly overweight, non-smoker, worked in steel mills for a few years, and fairly good health otherwise.
I know how fortunate I am to have had the determination and support to see the treatment through. Scrotal ultrasound revealed a homogeneous hypoechoic right testis without a mass and a heterogeneous mass containing multiple inhomogeneous cystic areas on the left side. This fact puts him into a higher risk group for testicular cancer.[5]Outside investigations encompassed a scrotal ultrasound as well as a CT of the pelvis. I am afraid of the surgery because i read on line that they cant always get the cancer cells out you only need one to be left behind.
I had CTs every three months for the next year, then every six months for two years and every year thereafter until the 10th year (2009) when oncology ran out of protocol for me. Further investigation in our institution included laboratory workup, ultrasound of both testes, as well as CT-scan of the chest, abdomen, and pelvis. I dont know what to do can you give me some suggestions or if someone has had the same thing happen to them.
I am lucky that the woman who loves me was the one who pushed me to get examined, treated, and have this addressed. She loves our new apartment and it just about drives me mad when I think she might lose it and even become homeless.
Treatment encompassed bilateral orchiectomy.ResultsScrotal examination revealed a hard and slightly tender mass that measured approximately 6 ? 7 cm on the left side.
However, metastatic bilateral testicular cancer of different histology is a challenging situation for the urologist, which warrants further discussion.
On the right side, a very small testis with a hard nontender mass at the lower pole was noted that measured approximately 1 ? 2 cm.
I have been told it can come back anytime, so I will continue to be vigilant but my odds have improved considerably over the years. It is now 3 years since my surgery, and at my last scan the surgeon wished me an great rest of my life, and he wouldn’t be seeing me again.


In the right inguinal region, an enlarged lymph node, suspicious for metastatic disease, was palpable. I was for quite a few years her caretaker, and now suddenly it is more and more she who is having now to help me with things.
He said the chances of a recurrence are never zero, but that the recurrence rates go down steeply in the first three years.
Sometimes I wish I could just die soon so the financial situation would now be known to be secure for my wife. The first symptom I noticed was blood in my urine, immediately followed by pain I thought was a kidney stone.
I had been tired for sometime and I’d wake up with an aching back but chalked it up to overdoing and being overtired. My husband and I set about making wills, getting finances in order and making sure that there would be any loose ends when it was over and I fully expected for it to be over in the not too distant future. The outside report of a pelvic CT described a soft tissue mass in the right inguinal region.
The odds were wrong and I truly believe there are things I am still meant to do and that God’s hand is in it all.
A left radical inguinal orchiectomy and a right inguinal testicular exploration were performed. The soft tissue mass in the right groin revealed metastatic seminoma (5.4 cm, one of three lymph nodes), which was positive for extracapsular extension. International Germ Cell Consensus Classification: A prognostic factor-based staging system for metastatic germ cell cancers. The overall 5-year progression-free survival is estimated at 80%.[8]Treatment Options, Relative to Stage and Histological OriginAt the moment, we are unable to verify whether the retroperitoneal lymph node is affected by the NSGCT or the seminoma. By contrast, the adequate adjuvant treatment in this case, but with positive retroperitoneal lymph nodes is a higher radiation dose (36 Gy). If the patient is not willing to undergo radiation, chemotherapy (cisplatin, etoposide and bleomycin 3 three cycles or etoposide and cisplatin 3 four cycles) is the alternative treatment option, followed by retroperitoneal lymph node dissection (RPLND) if a residual retroperitoneal mass is detected on follow-up imaging.
At the current time point, we are unable to verify whether the retroperitoneal lymph node is affected by the NSGCT or the seminoma.
Consequently, we determined four cycles of cisplatin, etoposide, and bleomycin to be the appropriate adjuvant treatment.ConclusionBilateral detected testicular neoplasm is a rare situation, and to the authors' knowledge, at present there is no case reported of a patient affected by synchronous testicular cancer of different histology. Kennedy BJ, Torkelson JL, Fraley EE: Adjuvant chemotherapy for stage II nonseminomatous germ cell cancer of the testis. Heidenreich A, Thuer D, Polyakov, S: Postchemotherapy retroperitoneal lymph node dissection in advanced germ cell tumours of the testis.



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