30.12.2013

Side effects of cancer treatment in dogs

Lung cancer is a very serious disease on which your chances of survival will greatly improve with the proper treatment. There are different types of treatment for lung cancer, including surgery, radiation therapy and chemotherapy.
Radiation therapy is an option for lung cancer patients who can’t go through surgery, like the elderly or those with other chronic health problems.
Chemotherapy is successful in prolonging the life of cancer patients who are already in good general health.
According to Oncology Channel, the 5-year survival rate of lung cancer patients with primary lung cancer jumps from 10 percent to 35 to 40 percent after surgically removing cancer that has not spread from the lung. WebMD Expert BlogsTales from the Pet Clinicwith Ann Hohenhaus, DVM, DACVIMThis blog has been retired. If you visit a friend in the hospital, you are likely to notice their doctor is treating them with intravenous fluids.
Veterinarians and physicians use fluid therapy for exactly the same reasons: to treat dehydration, to increase low blood pressure, to replace fluids lost through vomiting and diarrhea or hemorrhage, and to provide fluids to animals during anesthesia or who may be unable to drink due to illness.
The fluid dripping from a plastic bag into your doga€™s leg is being administered through the most common and direct route a€“ intravenously. Many cat owners manage the dehydration associated with chronic kidney disease by giving fluids at home. Fluids can be given as often as once a day or less frequently to meet the cata€™s fluid needs.
If you have a sick pet, ask your veterinarian if subcutaneous fluids might be helpful as home care. Several studies show that the extract of Milk Thistle seeds (Silybum marianum), particulary the phytochemicals silibinin and silymarin not only protect delicate kidney cells and tubules from damage, but also protect nerve cells from damage and the development of chemotherapy induced nerve pain. Researchers discovered that kidney damage occurs primarily within one hour after chemotherapy administration with the platinum based drugs cisplatin, carboplatin and oxaliplatin which are administered intravenously (IV) for a variety of cancers.  Therefore it is important to give milk thistle extract before chemotherapy is infused. Research has also shown that substances that increase our body’s own innate oxidation control may offer further protection. Supplements which increase SOD (super oxide dismutase) within cells include sulphur containing forms of selenium such as selenomethionine and methylselenocysteine. Silymarin and other components of Milk Thistle may increase our own super antioxidant glutathione.  Both N Acetyl Cysteine and Undenatured Whey protein are known to improve the availability of glutathione as a free radical scavenger within cells. Whey Protein is an outstanding source of high quality concentrated protein so important to patients undergoing chemotherapy which is a very high energy demanding state requiring extra nutrients and extra protein at a time when many patients lose their appetite or feel nauseous and do not want to eat.
Studies show that when silymarin from milk thistle seeds was administered before platinum chemotherapy there was a marked decrease in kidney cell damage. Oxidative stress and kidney damage may peak within one hour of drug exposure, the damage continues on until it is quenched by anti-oxidants.
Good management in an Integrative Cancer Care plan involves careful selection of  high quality botanical  and nutritional supplements that will mitigate side effects without interfering the therapeutic actions of the cancer treatment while at the same time offering protection from toxicity and damage as well and preserving  normal function.  This will be different with different drugs. Milk Thistle is an herbal medicine that is a multi-tasker and has many effects on cancer physiology as well as its protective effects against kidney damage and loss of kidney function. It is one of the main herbs used to protect the kidneys from the chemotherapy side effects of cisplatin, oxaliplatin and carboplatin.
Patients receiving platinum chemotherapy drugs also experience the side effect of neuropathy or nerve damage and nerve pain, usually in the hands and feet. L-Carnitine, L-Glutamine, Lipoic Acid, N-Acetyl-Cysteine as well as Omega 3 Fatty Acids are a good strategy for restoring healthy nerve function after chemotherapy. Acupuncture is also a useful supportive therapy for patients undergoing chemotherapy, radiation therapy, surgery and suffering from side effects of hormonal treatments.


Learning to choose foods rich in antioxidants will give you even more protection on a daily basis. This website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional.
The other name for the Butterfly Rash is malar rash and it mainly appears at the cheek bone area. It removes the cancer by taking out either the tumor, the infected lobe of the lung or the entire lung. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. If you visit your pet in the veterinary hospital, you will notice the same may be true a€“ clear fluid is dripping intravenously through a catheter. In emergency situations and when intravenous catheters cannot be easily placed, fluids can be administered into the hollow center of a leg or arm bone. The same types of fluids we normally administer intravenously are given under the skin, more scientifically called subcutaneous fluids.
The cata€™s blood vessels slowly absorb the fluid from the subcutaneous space, providing additional fluid to help the ailing kidneys. We can give nutrition intravenously but the fluid administered contains the building blocks of food a€“ amino acids, lipids, and sugar.
Ann Hohenhaus, a practicing veterinarian for 25 years, is board certified in both oncology and internal medicine. Components of Milk Thistle have also been shown to enhance the effects of some chemotherapy agents. This seems to decrease the high levels of oxidative stress that contribute to kidney cell damage. Although we most often think of whey as a source of high quality protein, it is also a source of precursors and greatly enhances the quenching of oxidative stress within cells which is key in reducing the toxic and damaging effects of chemotherapy. A protein drink if often an easy and satisfying source of much needed nutrients and calories.
Remarkably, normal cells were protected and there was no apparent interference with or reduction of effect of the platinum chemotherapy drugs. Therefore it is important to consult with a health care professional with experience and knowledge of drug-nutrient and drug-herb interactions. In fact some drug-herb and drug-nutrient interactions actually may enhance and improve drug efficacy and may even decrease chemo-resistance which is the predicament wherein cancer cells adapt and change so that they are no longer effected by the drugs.  Some cancer cells are so smart that they develop a pump mechanism for moving the toxic drug back outside of the cell!!! This is one reason cancer is so challenging to treat.
Milk Thistle is well known as an herb that enhances inflammation function and protects liver function.
Both Acupuncture as well as Milk thistle has also been traditionally used to normalize liver dysfunction and associated nausea side effects of chemotherapy.
Protective effect of silibinin. Di Cesare Mannelli L, Zanardelli M, Failli P, Ghelardini C.
Role of endogenous sulfur containing nucleophiles in an in vitro model of cis-diamminedichloroplatinium-induced nephro- toxicity.
You should not use the information on this website for diagnosing or treating a health problem or disease, prescribing any medication or other treatment, or discontinuing any medication or treatment recommended by your healthcare provider. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment.


Fluids may also be administered into the abdominal cavity, but fluid administered this way does not enter the blood vessels as rapidly, making it a less than ideal route of administration in emergency situations. Administering nutrition intravenously is called parenteral nutrition and is reserved for patients with a nonfunctioning intestinal tract.
This is one reason they kill fast growing cancer cells, but it is also why cells with higher rates of turnover and metabolism such as nerve cells, brain cells, heart muscle, the lining of the digestive tract, hair follicles and kidney tubules are so vulnerable to chemotherapy drug side effects with agents that act on cancer cells by increasing oxidative stress. All the better to find ways to improve treatments and decrease side effects and drug resistance. It is therefore a suitable herb to consider for patients undergoing and recovering from exposure to toxic chemicals and drugs. Therefore quenching the cascade of damaging electrons and providing nourishment for the restoration of healthy nerve function is essential as chemotherapy induced neuropathy may linger as a long term side effect. This skin ailment can also take place as an outcome of other diseases  like Pellagra, dermatomyositis and Bloom Syndrome. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. Fluid composition must also mimic the composition of blood with regard to the content of sodium, potassium, chloride and pH; if it does not, vital organs could be damaged by fluid therapy. Eating a wide range of color in your diet guarantees that you are eating a diet rich in antioxidants.
Those are people who chose to cure lung cancer using herbal remedies, or using the medical treatment.
ExpandThe opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. Some fluids have extra components like calcium, magnesium, dextrose (sugar), and bicarbonate. Veterinarians do supplement intravenous fluids with intravenous sugar (glucose) for patients with low blood sugar from an insulin overdose or a serious infection resulting in low blood sugar. Never delay or disregard seeking professional medical advice from your physician or other qualified health provider because of something you have read on WebMD. So you have to make sure that proper treatment is done in this case.The Butterfly Rash can take place in form of periodic attacks.
The patienta€™s medical condition dictates which of the various preparations of intravenous fluids should be used.
You may have these allergic diseases when you are suffering from ailments like rosacea, windburn, scarlet fever, dermatomyositis, and pellagra. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.
Some of these opinions may contain information about treatments or uses of drug products that have not been approved by the U.S.




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