28.12.2013

Natural treatments for colorectal cancer young

Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Dr Seow Choen is an experienced colorectal surgeon at Seow Choen Colorectal Centre in Singapore. Since its opening in July, 2004, the New City Osaki Clinic has been providing a€?highly active NK (natural killer) cell therapya€? to more than 800 cancer patients. It is generally considered, however, that a€?overall survival timea€? or a€?survival ratea€? rather than a change in the size of cancer should be examined in order to precisely evaluate the therapeutic efficacy.
Among many types of cancer, pancreatic cancer is known to have an especially low five-year survival rate worldwide (see a€?International comparison of cancer survival rate by sitea€? on the website of the National Cancer Center). Not the shrinking of cancer, but survival time (that is to say, how much the therapy prolonged life) most precisely represents the therapeutic efficacy for cancer. In general, when we look at survival time, we often use the median survival time (how long half of the patients survived after the start of treatment), but here we will review a one-year survival rate (the proportion of patients who survived for a year after the start of treatment), which is relatively easy to understand. Clinical studies of anticancer agents are conducted in patients with inoperable locally advanced or metastatic cancer in good overall conditiona€”those who can perform light work (PS 0-1), for example. The one-year survival rate in the treatment with Gemzar is still as low, however, at around 20%.
In Japan, TS-1 was approved and began to be used as the second anticancer agent for the treatment of pancreatic cancer. As shown in the above graph, according to the reports from the National Cancer Center, which is a representative hospital specializing in cancer in Japan, and from overseas, the one-year survival rate of patients with pancreatic cancer ranges from 20% to 30%. Please look at the survival time of the patients with pancreatic cancer who received highly active NK cell therapy at least four times (27 patients).
We recommended simultaneous use of anticancer agents, which is expected to produce synergistic effect, and therefore, about 80% of the patients concomitantly used anticancer agents. Even if we exclude the eight patients whose pancreas had been removed (who came to our clinic for the treatment of recurrence or distant metastasis after resection) and examine the remaining 19 patients whose pancreas was unresectable (because the rate after resection of the pancreas is known to be as high as 50 to 70%), our therapy turns out to be effective, having a one-year survival rate of 58%. These results indicate a marked extension of survival when compared with the median survival time in the current treatment in general, which is around ten months.
Pancreatic cancer progresses rapidly, and it is one of the most difficult-to-treat cancers. Severe asthma lung cancer emphysema (damage to the millions of tny air sacs in the lungs due to smoking) and cystic fibrosis (a genetic disorder that causes infections associated with lung cancer chronic lung infections) are among the more serious lung diseases or What are Some of the Lung Cancer Deaths Related To can lung cancer feel like heartburn Smoking Symptoms That May Indicate Lung Disease? Passive or second-hand smoking lung cancer incidence by race (breathing in other people’s smoke) is also linked to lung cancer.
Weight gain after weight loss surgery really falls into 2 broad categories: 1) The surgery is failing the patient (aka anatomic failure). The most frequent type of cancer was pancreatic cancer, followed by lung cancer, colorectal cancer, gastric cancer, and hepatoma.


One of the evaluation methods for the therapeutic efficacy of anticancer agents is the method according to the RECIST guideline, which is recognized worldwide. At our clinic, we believe that the most important criterion for efficacy is how long patients can live in a good condition with cancer. We think that, if we examine the efficacy of highly active NK cell therapy of the New City Osaki Clinic for the treatment of pancreatic cancer, we would be able to speculate the efficacy for other types of cancer.
Therefore, we followed up 27 patients with pancreatic cancer who received immune therapy at least four times at our clinic and examined the survival time from the time of diagnosis of pancreatic cancer to the present. This is because, if patients have to lie down and rest occasionally and it is difficult to even go out for shopping (PS 2-3), the side effects and other factors would affect the treatment outcome. The efficacy of Gemzar in prolonging survival and alleviating pain was demonstrated in clinical studies and this agent became the worlda€™s first anticancer agent for pancreatic cancer. The high efficacy of the combination of Gemzar and Tarceva (name of the compound: erlotinib) attracted attention in 2006 as it was shown to increase the one-year survival rate to 24% compared with 17% in treatment with Gemzar alone, but in terms of the median survival time, the improvement was only by two weeks. As shown in the graph, the treatment outcome was two or three times better than that of the treatment with only anticancer agents, indicating a synergistic effect in the combined use.
In addition, the one-year survival rate of patients with distant metastasis and those with relatively poor general condition rated as PS 2-3 is 63% and 58%, respectively. When we examined the immunity of these patients over time, it was characterized by an early several-fold increase in the NK cell count, NK activity, and NKG2D-positive lymphocyte count resulting from repeated highly active NK cell therapy and long-term maintenance of such increase.
However, combined use of anticancer agents and highly active NK cell therapy has an efficacy that cannot be obtained in the treatment with anticancer agents alone.
The vet will look for the presence of any lung tumors the size of the tumors as well as fluid in small cell lung cancer association with smoking the chest cavity. It Lung Cancer Deaths Related To Smoking was only in the lung during stage one the cancer is found and in the form of small tumors in the early stages. Some biomarkers include: Epidermal growth factor receptor (EGFR) Anaplastic lymphoma kinase (ALK) K-ras mutations (KRAS 1). This guideline focuses on the change in size of cancer and has the advantage of being able to rate the efficacy in a short time in the form of response rates.
Leta€™s compare the results with the published data on the treatment of pancreatic cancer only with anticancer agents. The general condition of 12 of these patients was already poor, rated as PS 2-3, at the start of the treatment, so this result was obtained under worse conditions than those of the above-mentioned clinical studies on anticancer agents. These data demonstrate that we can expect a substantial increase in the one-year survival rate in the combined use of anticancer agents and highly active NK cell therapy over the treatment with anticancer agents alone, even in patients with advanced metastatic cancer, or those with relatively poor general condition, who have to lie down and rest occasionally. Thus, the therapy which makes the best use of the a€?quantity and qualitya€? of the administered NK cells proved successful.
It should now be clear that major enhancement of the bodya€™s immunity and its maintenance are crucial components of cancer treatment.


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The highest rates of lung cancer in men are found in the Maori population of New Zealand, and in several African-American groups, including the black Yet most of these lung cancer deaths could be prevented. The risk of lung cancer is higher in people who have lived for many years in a house contaminated by radon. If the original lung cancer has spread, a person may feel symptoms in other places in the body.
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Therefore, TM with its low toxicity profile and good oral bioavailability is a potentially novel candidate to control tumor metastasis in head and neck cancer patients.



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